Results 61 to 70 of about 41,715 (245)
The focus of the current issue 3/2015 of GMS Medizin – Bibliothek – Information is the annual conference 2015 of the German Medical Libraries Association in Mannheim. The motto of the conference was “Libraries in progress”. The authors in this issue are
Bauer, Bruno
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This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
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This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
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“AGMB 2024: Shaping the change – Health information efficient.digial.innovative” was the theme of the annual conference of the German Medical Library Association (AGMB), held in Mainz from September 16 to 18, 2024. The annual meeting was organized by the
Hable, Sieglinde
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Traditionally, the yearly conference of the Arbeitsgemeinschaft für Medizinisches Bibliothekswesen e.V. (German Medical Library Association) is the central continuing education event for librarians and information specialists working in all types of ...
Reimann, Iris, Semmler-Schmetz, Martina
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
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ZB MED – Information Center for Life Sciences is the largest library worldwide in the field of life sciences. From October 2016 to June 2018 Dietrich Nelle was its interim managing director.
Bauer, Bruno, Nelle, Dietrich
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This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
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[english] The University Library of the Medical University of Vienna, founded in 2004, is the most extensive medical library in Austria. It possesses an outstanding medical-historic stock which is basically stored in its Branch Library of Medical History.
Albrecht, Harald+2 more
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