Results 61 to 70 of about 41,715 (245)

Bibliotheken im Fluss

open access: yesGMS Medizin – Bibliothek – Information, 2015
The focus of the current issue 3/2015 of GMS Medizin – Bibliothek – Information is the annual conference 2015 of the German Medical Libraries Association in Mannheim. The motto of the conference was “Libraries in progress”. The authors in this issue are
Bauer, Bruno
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

„AGMB 2024: Den Wandel steuern“. Jahrestagung der Arbeitsgemeinschaft für Medizinisches Bibliothekswesen (AGMB) e.V. vom 16. bis 18. September in Mainz

open access: yesGMS Medizin – Bibliothek – Information
“AGMB 2024: Shaping the change – Health information efficient.digial.innovative” was the theme of the annual conference of the German Medical Library Association (AGMB), held in Mainz from September 16 to 18, 2024. The annual meeting was organized by the
Hable, Sieglinde
doaj   +1 more source

Quo vadis AGMB? Ergebnisse der Online-Mitgliederbefragung 2019 sowie Ausblick auf mögliche Konsequenzen für die AGMB

open access: yesGMS Medizin – Bibliothek – Information, 2019
Traditionally, the yearly conference of the Arbeitsgemeinschaft für Medizinisches Bibliothekswesen e.V. (German Medical Library Association) is the central continuing education event for librarians and information specialists working in all types of ...
Reimann, Iris, Semmler-Schmetz, Martina
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

10 Fragen von Bruno Bauer an Dietrich Nelle, den Interimsdirektor von ZB MED – Informationszentrum Lebenswissenschaften

open access: yesGMS Medizin – Bibliothek – Information, 2018
ZB MED – Information Center for Life Sciences is the largest library worldwide in the field of life sciences. From October 2016 to June 2018 Dietrich Nelle was its interim managing director.
Bauer, Bruno, Nelle, Dietrich
doaj   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Josephinische Bibliothek und medizinhistorische Bestände der Universitätsbibliothek der Medizinischen Universität Wien [The Josephinian Library and the medical-historic stock of the University Library of the Medical University of Vienna]

open access: yesGMS Medizin – Bibliothek – Information, 2012
[english] The University Library of the Medical University of Vienna, founded in 2004, is the most extensive medical library in Austria. It possesses an outstanding medical-historic stock which is basically stored in its Branch Library of Medical History.
Albrecht, Harald   +2 more
doaj   +1 more source

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