Results 61 to 70 of about 321,149 (261)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Special Libraries, April 1940 [PDF]

open access: yes, 1939
Volume 31, Issue 4https://scholarworks.sjsu.edu/sla_sl_1940/1003/thumbnail ...
Special Libraries Association
core   +4 more sources

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

open access: yesMolecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban   +12 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Special Libraries, December 1964 [PDF]

open access: yes, 1963
Volume 55, Issue 10https://scholarworks.sjsu.edu/sla_sl_1964/1009/thumbnail ...
Special Libraries Association
core   +2 more sources

Emil du Bois-Reymond on "The Seat of the Soul" [PDF]

open access: yes, 2014
The German pioneer of electrophysiology, Emil du Bois-Reymond (1818–1896), is generally assumed to have remained silent on the subject of the brain. However, the archive of his papers in Berlin contains manuscript notes to a lecture on “The Seat of the ...
Finkelstein, Gabriel
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

„AGMB 2024: Den Wandel steuern“. Jahrestagung der Arbeitsgemeinschaft für Medizinisches Bibliothekswesen (AGMB) e.V. vom 16. bis 18. September in Mainz

open access: yesGMS Medizin – Bibliothek – Information
“AGMB 2024: Shaping the change – Health information efficient.digial.innovative” was the theme of the annual conference of the German Medical Library Association (AGMB), held in Mainz from September 16 to 18, 2024. The annual meeting was organized by the
Hable, Sieglinde
doaj   +1 more source

Quo vadis AGMB? Ergebnisse der Online-Mitgliederbefragung 2019 sowie Ausblick auf mögliche Konsequenzen für die AGMB

open access: yesGMS Medizin – Bibliothek – Information, 2019
Traditionally, the yearly conference of the Arbeitsgemeinschaft für Medizinisches Bibliothekswesen e.V. (German Medical Library Association) is the central continuing education event for librarians and information specialists working in all types of ...
Reimann, Iris, Semmler-Schmetz, Martina
doaj   +1 more source

Hypomethylating agents increase L1 retroelement expression without inducing novel insertions in myeloid malignancies

open access: yesMolecular Oncology, EarlyView.
We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová   +14 more
wiley   +1 more source

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