Results 61 to 70 of about 1,022,480 (312)

DeepGreen – DeepGold: Open-Access-Transformation – Entwicklung und Perspektiven

GMS Medizin – Bibliothek – Information, 2019
The DeepGreen project () is developing an automated workflow to transfer scholarly publications from publishers to repositories for open access publishing.
Rusch, Beate, Boltze, Julia, Dierkes, Thomas, Goltz-Fellgiebel, Julia Alexandra, Staub, Hedda   +4 more
doaj   +1 more source

Characterising a homozygous two‐exon deletion in UQCRH: comparing human and mouse phenotypes

EMBO Molecular Medicine, 2021
Mitochondrial disorders are clinically and genetically diverse, with isolated complex III (CIII) deficiency being relatively rare. Here, we describe two affected cousins, presenting with recurrent episodes of severe lactic acidosis, hyperammonaemia ...
Silvia Vidali, Raffaele Gerlini, Kyle Thompson, Jill E Urquhart, Jana Meisterknecht, Juan Antonio Aguilar‐Pimentel, Oana V Amarie, Lore Becker, Catherine Breen, Julia Calzada‐Wack, Nirav F Chhabra, Yi‐Li Cho, Patricia da Silva‐Buttkus, René G Feichtinger, Kristine Gampe, Lillian Garrett, Kai P Hoefig, Sabine M Hölter, Elisabeth Jameson, Tanja Klein‐Rodewald, Stefanie Leuchtenberger, Susan Marschall, Philipp Mayer‐Kuckuk, Gregor Miller, Manuela A Oestereicher, Kristina Pfannes, Birgit Rathkolb, Jan Rozman, Charlotte Sanders, Nadine Spielmann, Claudia Stoeger, Marten Szibor, Irina Treise, John H Walter, Wolfgang Wurst, Johannes A Mayr, Helmut Fuchs, Ulrich Gärtner, Ilka Wittig, Robert W Taylor, William G Newman, Holger Prokisch, Valerie Gailus‐Durner, Martin Hrabě de Angelis   +43 more
doaj   +1 more source

The Performance of Knowledge: Pointing and Knowledge in Powerpoint Presentations [PDF]

, 2008
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Knoblauch, Hubert
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Impaired mitochondrial ketone body oxidation in insulin resistant statesResearch in context

EBioMedicine
Summary: Background: Reduced mitochondrial respiratory function has been implicated in metabolic disorders like type 2 diabetes (T2D), obesity, and metabolic dysfunction-associated steatotic liver disease (MASLD), which are tightly linked to insulin ...
Elric Zweck, Sarah Piel, Johannes W. Schmidt, Daniel Scheiber, Martin Schön, Sabine Kahl, Volker Burkart, Bedair Dewidar, Ricarda Remus, Alexandra Chadt, Hadi Al-Hasani, Lucia Mastrototaro, Hug Aubin, Udo Boeken, Artur Lichtenberg, Jörg Distler, Amin Polzin, Malte Kelm, Ralf Westenfeld, Robert Wagner, Patrick Schrauwen, Julia Szendroedi, Michael Roden, Cesare Granata   +23 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Utilization of psychotherapy, pharmacotherapy, and their combination by individuals with current or residual depression: results from five annual nationally representative German surveys

Scientific Reports
Depression is a common and burdensome mental disorder affecting more than 320 million people worldwide. Clinical practice guidelines recommend psychotherapy, antidepressant pharmacotherapy, or their combination as the cornerstones of evidence-based ...
Louisa Breuer, Andreas Czaplicki, Ulrich Hegerl, Hanna Reich   +3 more
doaj   +1 more source

Methodological tests of the use of trace elements as tracers to assess root activity [PDF]

, 2014
peer-reviewedN.J.H. was funded by the Irish Research Council, co-funded by Marie Curie Actions under FP7. The field experiments A, B and G were supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under the grant agreements ...
Buchmann, Nina, Finn, John, Gockele, A., Hoekstra, Nyncke J., Landert, L., Luscher, L., Prill, N., Scherer-Lorenzen, M.   +7 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Mental symptoms in post-COVID syndrome and post-COVID-19 vaccination syndrome: results of a representative population survey

Frontiers in Public Health
BackgroundMental symptoms such as fatigue, concentration difficulties, and sleep disorders are frequently reported in both Post-COVID Syndrome (PCS) and Post-COVID-19 Vaccination Syndrome (PCVS).
Andreas Czaplicki, Leonie Hipper, Ulrich Hegerl, Ulrich Hegerl   +3 more
doaj   +1 more source