Results 71 to 80 of about 27,772,219 (267)

Providing and accessing scientific literature. How the German Research Foundation (DFG) supports scholarly communication

Information Services & Use, 2006
Within the DFG the Committee on Academic Libraries and Information Systems is traditionally responsible for the management of funding activities for libraries and archives. Formerly known as the Library Committee the change of its name reflects major developments in the exchange of research information.
Gersmann, Gudrun, Fournier, Johannes, German Research Foundation (DFG)   +2 more
openaire   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Correction: Corrigendum: A connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics

Nature Communications, 2017
Nature Communications 8: Article number: 14530 (2017); Published 21 February 2017; Updated 21 March 2017 The financial support for this Article was not fully acknowledged.
Victoria A. Lukashkina, Snezana Levic, Andrei N. Lukashkin, Nicola Strenzke, Ian J. Russell   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Real-Time Loss Tools: Open-Source Software for Time- and State-Dependent Seismic Damage and Loss Calculations – Features and Application to the 2023 Türkiye-Syria Sequence

Seismica
During a seismic sequence, the action of each earthquake has the potential to damage and weaken exposed structures, causing their fragility to change, and increasing their likelihood of being further damaged by subsequent earthquakes.
Cecilia Nievas, Helen Crowley, Graeme Weatherill, Fabrice Cotton   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The association between feelings of loneliness and the number of social relationships in depression: a cross-sectional study of German adults

BMC Psychiatry
Background Depression is a common psychiatric disorder that is associated with both feelings of loneliness and withdrawal from social relationships. However, clinical experience suggests that feelings of loneliness are an integral part of depressive ...
Valeria Koppert, Andreas Czaplicki, Ulrich Hegerl   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Links between self-monitoring data collected through smartphones and smartwatches and the individual disease trajectories of adult patients with depressive disorders: Study protocol of a one-year observational trial

Contemporary Clinical Trials Communications
Depression is highly recurrent and heterogenous in its individual course, requiring a personalized treatment approach. Patients today can collect large volumes of personal data via smartphones and smartwatches and may utilize them for their treatment and
Hanna Reich, Simon Schreynemackers, Rebeka Amin, Sascha Ludwig, Jil Zippelius, Johannes Leimhofer, Tobias Dunker, Elisabeth Schriewer, Angela Carell, Yvonne Weber, Ulrich Hegerl   +10 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source