Results 71 to 80 of about 167,769 (338)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Prospects and possibilities of germanium extraction from the Bigan coal deposit

Мінеральні ресурси України
The article is devoted to lignite deposits of Zakarpattia, which contain germanium, in particular, the Bigan deposit and methods of extracting germanium from this deposit.
M. S. Burlutskyy, S. F. Lytvyniuk
doaj   +1 more source

Method of Fabricating Schottky Barrier solar cell [PDF]

, 1982
On a thin substrate of low cost material with at least the top surface of the substrate being electrically conductive is deposited a thin layer of heavily doped n-type polycrystalline germanium, with crystalline sizes in the submicron range.
Stirn, R. J., Yeh, Y. C. M.
core   +1 more source

Pulse shape simulation for segmented true-coaxial HPGe detectors [PDF]

, 2010
A new package to simulate the formation of electrical pulses in segmented true-coaxial high purity germanium detectors is presented. The computation of the electric field and weighting potentials inside the detector as well as of the trajectories of the ...
Abt, I., Caldwell, A., Lenz, D., Liu, J., Liu, X., Majorovits, B.   +5 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Prediction of new sp3 silicon and germanium allotropes from the topology-based multiscale method

, 2017
This article continues our recent publication [I.A. Baburin and D.M. Proserpio and V.A. Saleev and A.V. Shipilova, Phys. Chem. Chem. Phys.17, 1332 (2015)] where we have presented a comprehensive computational study of sp3 carbon allotropes based on the ...
Fadda, Giuseppe, Proserpio, Davide, Saleev, Vladimir, Shipilova, Alexandra   +3 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Grading of germanium contents and establishment of standard for germanium-enrichment in cultivated soils in Guizhou Province

Carsologica Sinica
Germanium is a rare and dispersed element in nature. Positioned between metals and non-metals on the periodic table, germanium possesses properties of both groups.
Hua MA, Dawei CAI, Mingqiang REN, Longbo LI   +3 more
doaj   +1 more source

Molecular Dynamics Investigation of the Mechanical Properties of Germanium Reinforced with Iron Nanoparticles at Different Speeds [PDF]

مجله مدل سازی در مهندسی
Considering the wide application of germanium in nano devices and its high density compared to silicon and the possibility of its dislocation and diffusion in grain boundaries, improving its properties is of great importance. In this study, with the help
Majid Samadiyan, Masoud Ajri
doaj   +1 more source

Direct Band-gap 1.64μm Electroluminescence from Edge Emitting Germanium Diode for Near-infrared Application [PDF]

, 2023
Jiayin Yang, Lei Chen, Long Zhang, Kaili Xiong   +3 more
openalex   +1 more source