Results 191 to 200 of about 3,120,902 (290)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Effect of the Transradial Approach on Wrist Function in Diagnostic Cerebral Angiography. [PDF]

Healthcare (Basel)
Kifmann J, Braun M, Steinhart J, Sollmann N, Kloth C, Pedro M, Dreyhaupt J, Beer M, Schmitz B, Rosskopf J.   +9 more
europepmc   +1 more source

Germany

IMF Staff Country Reports, 2022
openaire   +1 more source

New perspectives, new practices and tensions in German language and literature teaching: on identity, insurgent, decolonial and anti-racist crises and demands

Cleydia Regina Esteves, Érica Schlude Wels, Ivanete da Hora Sampaio, Cleydia Regina Esteves, Érica Schlude Wels, Ivanete da Hora Sampaio, Cleydia Regina Esteves, Érica Schlude Wels, Ivanete da Hora Sampaio, Cleydia Regina Esteves, Érica Schlude Wels, Ivanete da Hora Sampaio   +11 more
openalex   +2 more sources

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

[Anesthetic diversity: a pillar of healthcare system resilience and a strategic imperative in an era of uncertainty]. [PDF]

Anaesthesiologie
Kranke P, Kleinberg R, Meybohm P, Philip BK, Marin L, Zacharowski K.   +5 more
europepmc   +1 more source

History of Political relations between Germany and Kazakhstan in 1991-2025

A.G. Ochilova
openalex   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Retraction Note: Y-box protein-1/p18 fragment identifies malignancies in patients with chronic liver disease. [PDF]

BMC Cancer
Tacke F, Kanig N, En-Nia A, Kaehne T, Eberhardt CS, Shpacovitch V, Trautwein C, Mertens PR.   +7 more
europepmc   +1 more source