Results 41 to 50 of about 2,968,392 (291)
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Revista Katálysis, 2008 A questão de fundo do artigo diz respeito às possibilidades contidas na economia solidária para configurar vínculos não determinados pelo cálculo utilitário e materializar um regime singular entre distintos princípios operantes na vida econômica.
Luiz Inácio Germany Gaiger
doaj
Jews in Germany: from Ancient Times to the Present Day
RUDN Journal of World History, 2017 Antisemitism dates back to the remote past. Today it seems impossible to define whether antisemitism throughout centuries was stronger in Germany than in other European countries (France, Poland, and Russia) as from the point of view of historical ...
K Y Khderi
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Syria: the Geopolitical Alchemy [PDF]
Научно-аналитический вестник Института Европы РАН, 2018 The article examines objectives of the military attack undertaken by the US, Britain and France on Syria on April 14, 2014, under the pretext of responding to the use of chemical weapons by the "Assad regime" in Eastern Ghouta.
Danilov D.A.
doaj +1 more source
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
Night work and breast cancer estrogen receptor status – results from the German GENICA study
Scandinavian Journal of Work, Environment & Health, 2013 OBJECTIVES: The potential mechanisms that link night-shift work with breast cancer have been extensively discussed. Exposure to light at night (LAN) depletes melatonin that has oncostatic and anti-estrogenic properties and may lead to a modified ...
Sylvia Rabstein +15 more
doaj +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
FEBS Letters, EarlyView.TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling +4 more
wiley +1 more source