Results 261 to 270 of about 198,482 (318)

Mercaptans in malodorants break disulfide bridges in human serum albumin and form adducts suitable as biomarkers of exposure in vitro

open access: yesDrug Testing and Analysis, EarlyView.
Disulfide adducts of mercaptans with cysteine residues in human serum albumin were detected as tripeptides and dipeptides after proteolysis with proteinase K. All peptide adducts were detected simultaneously with a mass spectrometry‐based method working in the scheduled multiple reaction monitoring (sMRM) mode.
Paula Helena Sieber   +3 more
wiley   +1 more source

Stress analysis of crack characteristic of anthracite under dynamic loading

open access: yesDeep Underground Science and Engineering, EarlyView.
In this article, the dynamic compression test of anthracite under five strain rates is carried out, the evolution law of three kinds of crack characteristic stress is analyzed, and a prediction model of the crack characteristic stress threshold considering the strain rate effect is established. Then, the rationality of crack characteristic stress under
Yun Bai   +5 more
wiley   +1 more source

Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming   +14 more
wiley   +1 more source

The link of FOXO1 and FOXO4 transcription factors to development of the lens

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The FOXOs regulate the transcription of many genes, including ones directly linked to pathways required for lens development. However, this transcription factor family has rarely been studied in the context of development, including the development of the lens.
Rifah N. Gheyas   +3 more
wiley   +1 more source

Advancing RNAi-Based Strategies Against Downy Mildews: Insights Into dsRNA Uptake and Gene Silencing

open access: yes
Göl D   +10 more
europepmc   +1 more source

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