Results 1 to 10 of about 3,589 (175)
A comprehensive dataset of germinoma on MRI/CT with clinical and radiomic data [PDF]
Scientific DataIntracranial germ cell tumors (GCTs) are rare neoplasms with a peak incidence in adolescents. Germinoma is the most common histological subtype of intracranial GCTs.
Lixuan Huang +12 more
doaj +2 more sources
Management of CNS germinoma [PDF]
CNS Oncology, 2015 The following is a general overview of the management of CNS germinomas. Over the last 35 years, CNS germinomas have become one of the pediatric brain tumors with the best outcomes with a greater than 85% overall survival over 5 years. This is in part due to the fact that germinomas are very responsive to chemotherapy and radiation.
Jeffrey Allen, Diana Osório
exaly +3 more sources
Diagnosis and Management of Pineal Germinoma: From Eye to Brain
Eye and Brain, 2023 David Cohen,1 N Scott Litofsky2 1Department of Neurology, University of Missouri School of Medicine, Columbia, MO, USA; 2Department of Neurosurgery, University of Missouri School of Medicine, Columbia, MO, USACorrespondence: N Scott Litofsky, Department ...
N Scott Litofsky
exaly +2 more sources
Southern Medical Journal, 2010 Germinomas are gonadal neoplasms that rarely occur extragonadally in the midline structures of the human body. Newly diagnosed adult cases of pineal gland germinomas are very rare since most of the cases are diagnosed in the mid teens. The estimated incidence of this tumor in western countries is between 0.4-3.4%.
Nandakumar, Srinivasan +3 more
openaire +4 more sources
Pediatric Hematology Oncology Journal, 2022 The clinical utility of measuring cerebrospinal fluid placental alkaline phosphatase (CSF-PLAP) was evaluated in three patients with germinoma. CSF-PLAP was elevated in two patients with suprasellar germinoma who were symptomatic before developing ...
Satoshi Obu +13 more
doaj +1 more source
Baylor University Medical Center Proceedings, 2015 Pineal region tumors make up less than 1% of all intracranial neoplasms, with the majority being of germ cell origin. We describe the diagnostic evaluation and treatment of a patient presenting with neurological deficits who was found to have a germinoma of the pineal gland.
Manoj P, Reddy +6 more
openaire +2 more sources
Intracranial bifocal germinoma
Radiology Case Reports, 2022 Primary intracranial germ cell tumors are rare, often affecting children and young patients. Germinomas are the most common type of germ cell tumors. We present the case of a 10-year-old child, who was admitted with decreased visual acuity, asthenia, polyuro-polydipsic syndrome, and gait disorder.
Meriem Haloua +6 more
openaire +3 more sources
Case Report: Acquired Generalized Anhidrosis Caused by Brain Tumor: Review of the Literature
Frontiers in Endocrinology, 2022 PurposeThere has been limited focus on sweating failure in patients with brain tumor. We report two patients with generalized anhidrosis caused by germinoma. We also review previous reports of generalized anhidrosis due to brain tumor.Case ReportsPatient
Kohei Kawahara +6 more
doaj +1 more source
Pathogenesis of central nervous system germ cell tumors
Frontiers in Oncology, 2022 Intracranial germ cell tumors (IGCTs) are clinically rare. They are more common in children and adolescents and the incidence in Asia is higher than in Western countries.
Siyuan Liu +4 more
doaj +1 more source
PD-1/PD-L1 expression in a series of intracranial germinoma and its association with Foxp3+ and CD8+ infiltrating lymphocytes. [PDF]
PLoS ONE, 2018 One histopathological characteristic of intracranial germinoma is abundant tumor-infiltrating lymphocytes (TILs) showing a two-cell pattern with large undifferentiated tumor cells.
Bin Liu +12 more
doaj +1 more source