Results 121 to 130 of about 340,349 (250)

Novel Vβ Specific Germline Contacts Shape an Elite Controller T Cell Response

, 2020
Yang Wang, Alexandra Tsitsiklis, Wei Gao, Hunghao Chu, Yan Zhang, Wei Li, Wing Ki Wong, Charlotte M. Deane, David B. Neau, Jill E. Slansky, Paul G. Thomas, Ellen A. Robey, Shaodong Dai   +12 more
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Incidence and Prognostic Impact of Deleterious Germline Mutations in Primary Advanced Ovarian Carcinoma Patients [PDF]

, 2023
Majdi Imterat, Philipp Harter, Kerstin Rhiem, Florian Heitz, Stephanie Schneider, Nicole Concin, Malak Moubarak, Julia Welz, Vasileios Vrentas, Alexander Traut, Eric Hahnen, Rita K. Schmutzler, Andreas du Bois, Beyhan Ataseven   +13 more
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Accurate estimation of homologue-specific DNA concentration-ratios in cancer samples allows long-range haplotyping [PDF]

, 2011
Interpretation of allelic copy measurements at polymorphic markers in cancer samples presents distinctive challenges and opportunities. Due to frequent gross chromosomal alterations occurring in cancer (aneuploidy), many genomic regions are present at ...
Gad Getz, Matthew Meyerson, Scott L. Carter   +2 more
core   +1 more source

Erratum: Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas [PDF]

, 2013
Claire Palles, Jean‐Baptiste Cazier, Kimberley Howarth, Enric Domingo, Angela M. Jones, Peter Broderick, Zoe Kemp, Sarah L. Spain, Estrella Guarino, Israel Salguero, Amy L. Sherborne, Daniel Chubb, Luis G. Carvajal‐Carmona, Yusanne Ma, Kulvinder Kaur, Sara E. Dobbins, Ella Barclay, Maggie Gorman, Lynn Martin, Michal Kováč, Sean Humphray, Anneke Lucassen, Chris Holmes, David L. Bentley, Peter Donnelly, Jenny C. Taylor, Christos Petridis, Rebecca Roylance, Elinor J. Sawyer, David Kerr, Susan K. Clark, Jonathan M. Grimes, Stephen Kearsey, Huw Thomas, Gil McVean, Richard S. Houlston, Ian Tomlinson   +36 more
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Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues [PDF]

, 2023
Rita Rebollo, Pierre Gerenton, Eric Cumunel, Arnaud Mary, François Sabot, Nelly Burlet, Benjamin Gillet, Sandrine Hughes, Daniel Siqueira de Oliveira, Clément Goubert, Marie Fablet, Cristina Vieira, Vincent Lacroix   +12 more
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Identification of Regulatory RNA-Binding Genes in Spermatogonial Stem Cell Reprogramming to ES-like Cells Using Machine Learning–Integrated Transcriptomic and Network Analysis

Cells
Spermatogonial stem cells (SSCs) are unipotent germline cells with emerging pluripotent potential under specific in vitro conditions. Understanding their capacity for reprogramming and the molecular mechanisms involved offers valuable insights into ...
Ali Shakeri Abroudi, Hossein Azizi, Hewa Khalid Abdullah, Marwa Fadhil Alsaffar, Thomas Skutella   +4 more
doaj   +1 more source

Case–control analysis identifies shared properties of rare germline variation in cancer predisposing genes [PDF]

, 2019
Mykyta Artomov, Joseph Vijai, Grace Tiao, Tinu Thomas, Kasmintan A. Schrader, Robert J. Klein, Adam Kieżun, Namrata Gupta, Lauren Margolin, Alexander Stratigos, Ivana K. Kim, Kristen Shannon, Leif W. Ellisen, Daniel A. Haber, Gad Getz, Hensin Tsao, Steven M. Lipkin, David Altshuler, Kenneth Offit, Mark J. Daly   +19 more
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PP121 Comparison of genomic and transcriptional homologous recombination deficiency assays in breast cancer patients with germline BRCA mutations

, 2022
H. Chae, S.H. Sim, Jae‐Hong Kim, W-J. Song, Y.J. Park, E-G. Lee, J.H. Han, S-Y. Jung, S. Lee, E.S. Lee, Yong‐Soon Kwon, K.S. Lee, S-Y. Kong   +12 more
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GENE-09. MUTATION SIGNATURE ANALYSIS IN AN ULTRAHYPERMUTATED MEDULLOBLASTOMA PREDICTS UNDERLYING GERMLINE POLYMERASE PROOFREADING DEFICIENCY IN A CHILD WITH CLINICAL FEATURES OF CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY SYNDROME [PDF]

, 2019
Holly Lindsay, Sarah Scollon, Jacquelyn Reuther, Horatiu Voicu, Surya P. Rednam, Kevin E. Fisher, Murali Chintagumpala, Donald W. Parsons, Adekunle M. Adesina, Sharon E. Plon, Angshumoy Roy   +10 more
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Data from Common Germline Risk Variants Impact Somatic Alterations and Clinical Features across Cancers

, 2023
Shinichi Namba, Yuki Saito, Yasunori Kogure, Tatsuo Masuda, Melissa L. Bondy, Puya Gharahkhani, Ines Gockel, Dominik Heider, Axel M. Hillmer, Janusz Jankowski, Stuart MacGregor, Carlo Maj, Beatrice Melin, Quinn T. Ostrom, Claire Palles, Johannes Schumacher, Ian Tomlinson, David C. Whiteman, Yukinori Okada, Keisuke Kataoka   +19 more
openalex   +1 more source