Results 221 to 230 of about 340,349 (250)
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Epigenetic germline inheritance
Current Opinion in Genetics & Development, 2004Our increased knowledge of epigenetic reprogramming supports the idea that epigenetic marks are not always completely cleared between generations. Incomplete erasure at genes associated with a measurable phenotype can result in unusual patterns of inheritance from one generation to the next.
Chong, SY, Whitelaw, E
openaire +3 more sources
2013
Stem cells support tissue maintenance by balancing self-renewal and differentiation. Germline stem cells (GSCs) belong to a kind of stem cells that are crucial to development and tissue homeostasis with their ability to both differentiate into gametes and maintain an undifferentiated state by their self-renewal property.
Ji, Wu, Huacheng, Luo, Hu, Wang
openaire +2 more sources
Stem cells support tissue maintenance by balancing self-renewal and differentiation. Germline stem cells (GSCs) belong to a kind of stem cells that are crucial to development and tissue homeostasis with their ability to both differentiate into gametes and maintain an undifferentiated state by their self-renewal property.
Ji, Wu, Huacheng, Luo, Hu, Wang
openaire +2 more sources
Nature Cell Biology, 2019
With the advent of efficient, easy-to-use genome editing by CRISPR-Cas9, editing human embryos is now possible, providing tremendous opportunities to study gene function and cell fate in early human development. The technique can also be used to modify the human germline.
Rebecca A. Lea, Kathy K. Niakan
openaire +2 more sources
With the advent of efficient, easy-to-use genome editing by CRISPR-Cas9, editing human embryos is now possible, providing tremendous opportunities to study gene function and cell fate in early human development. The technique can also be used to modify the human germline.
Rebecca A. Lea, Kathy K. Niakan
openaire +2 more sources
Reproductive BioMedicine Online, 2012
The aim of this study was to develop and perform a preimplantation genetic diagnosis (PGD) assay discriminating between wild-type and mutant alleles in two families with germline mosaicism. Family 1 had two children affected with severe myoclonic epilepsy (SCNA1A del exons 1-22).
Gheona, Altarescu +6 more
openaire +2 more sources
The aim of this study was to develop and perform a preimplantation genetic diagnosis (PGD) assay discriminating between wild-type and mutant alleles in two families with germline mosaicism. Family 1 had two children affected with severe myoclonic epilepsy (SCNA1A del exons 1-22).
Gheona, Altarescu +6 more
openaire +2 more sources