Results 211 to 220 of about 234,487 (302)

Colorectal Cancer Screening in Hereditary and Familial High‐Risk Populations: Best Practices and Future Directions

International Journal of Cancer, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related morbidity and mortality worldwide yet is largely preventable through effective screening and surveillance. While most CRC cases are sporadic, a substantial proportion occur in individuals at increased risk due to hereditary cancer syndromes or family history who require tailored
Ophir Gilad, Francesc Balaguer, Elizabeth E. Half, Kevin J. Monahan, Elena M. Stoffel, Sonia S. Kupfer   +5 more
wiley   +1 more source

The 2017 Keystone Symposium on HIV Vaccines

Human Vaccines & Immunotherapeutics, 2017
Christopher A. Cottrell, Andrew B. Ward
doaj   +1 more source

Sex differences in transcription-associated mutagenesis in the human germline. [PDF]

Genetics
Wyman MJ, Agarwal I, de Manuel M, Spisak N, Przeworski M.   +4 more
europepmc   +1 more source

The Association Between Human Papillomavirus and Prostate Cancer: A Systematic Review and Meta‐Analysis

International Journal of Cancer, EarlyView.
ABSTRACT Human papillomavirus (HPV), the necessary cause of cervical cancer, is associated with an increased risk of other anogenital cancers. While HPV has frequently been detected in prostate specimens, its role in prostate carcinogenesis remains controversial. We synthesized and meta‐analyzed the epidemiological literature on the association between
Sarah Botting‐Provost, Kristy Ng, Cassandra Laurie, Rodrigo Noorani, Mariam El‐Zein, Eduardo L. Franco   +5 more
wiley   +1 more source

The Role of Germline Transposable Element Insertions in Pediatric Cancer Predisposition. [PDF]

Cancer Res Commun
Sexton CE, Hamilton KV, Chu C, Ting DT, Garber JE, Park PJ, Kamihara J.   +6 more
europepmc   +1 more source

Global Real‐World Outcomes of Olaparib in Metastatic Castration‐Resistant Prostate Cancer Patients With Homologous Recombination Repair Alterations

International Journal of Cancer, EarlyView.
ABSTRACT Evidence to guide the treatment for patients with metastatic castration‐resistant prostate cancer (mCRPC) and Homologous Recombination Repair (HRR) gene alterations outside of clinical trials remains limited. This was an observational, cohort study, including mCRPC patients with tumor harboring HRR alterations, progressed on a prior androgen ...
Lorena Incorvaia, Daniele Santini, Marc R. Matrana, Marco Maruzzo, Ray Manneh Kopp, Lorenzo Antonuzzo, Sergio Bracarda, Deniz Tural, Giuseppe Procopio, Maria T. Bourlon, Orazio Caffo, Martin Ignacio Zapata Laguado, Massimo Di Maio, Brigida Anna Maiorano, Vincenza Conteduca, Sabrina Rossetti, Helga Lipari, Thomas Büttner, Mimma Rizzo, Yüksel Ürün, Carlo Messina, Fernando Sabino Marques Monteiro, Andrey Soares, Mattia Puglisi, Alice Principi, Eleonora Lai, Giulia Mammone, Marco Stellato, Ilaria Depetris, Tancredi Didier Bazan Russo, Isadora Yasbick Spricido, Camila Bobato Lara Gismondi, Francesco Massari, Nicola Pavan, Matteo Santoni, Tarek Taha   +35 more
wiley   +1 more source

Hair bulb and oral mucosa DNA for prompt germline testing in hematologic neoplasms. [PDF]

Blood Cancer J
Balbastre-Úbeda F, Torres-Esquius S, Gabarrós-Subirà M, Beas F, Leno-Colorado J, Sanchez-Morales C, Chen-Liang TH, Urban-Giral S, Tena-Alegre M, Hurtado AM, Casas-Tio MJ, Garrido AM, Acha P, Blanco A, Solé F, Del Rey M, Díez-Campelo M, Valcárcel D, Montoro MJ, Jerez A, Myelodysplastic Syndromes (GESMD).   +20 more
europepmc   +1 more source

Germline Cancer Predisposition and De Novo Contributions in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group

International Journal of Cancer, EarlyView.
ABSTRACT Approximately 6%–8% of children and adolescents with rhabdomyosarcoma (RMS) have an underlying cancer predisposition disorder (CPD), which varies between embryonal and alveolar subtypes and other clinical characteristics. Identifying a CPD remains challenging, as traditional approaches rely on clinical features and family history. Additionally,
Taylor M. Luckie, Sarah Scollon, Yao Yu, Aniko Sabo, Tiffany Chambers, Olga Taylor, Logan G. Spector, Michael E. Scheurer, Douglas S. Hawkins, Rajkumar Venkatramani, Chad D. Huff, Sharon E. Plon, Philip J. Lupo   +12 more
wiley   +1 more source

Impact of germline predisposition genes to hematologic malignancies on transplant outcomes and donor selection. [PDF]

Front Immunol
Li Z, Yang K, Zhang C, Wang X, Wang L, Li J, Wen X, Fei Q, Zhai J, Zhou Y, Ming Z, Song Y, Zhao Y, Wu T, Zheng Q.   +14 more
europepmc   +1 more source