Background A recent study has shown that it is possible to accurately estimate gestational age (GA) at birth from the DNA methylation (DNAm) of fetal umbilical cord blood/newborn blood spots.
Polina Girchenko +14 more
doaj +1 more source
Growth Hormone Therapy for Paediatric Growth Disorders: The Past, Present, and Future
Abnormal pituitary function was linked to excessive height and acromegaly in the late 19th century. Harvey Cushing proposed a pituitary substance that regulated human linear growth.
Martin O. Savage, Abdullah Alherbish
doaj +1 more source
Hematocrit: another important factor in systemic neonatal cardiovascular adaptation
Background: Global cardiovascular adaptation of normal healthy term newborns is rarely studied from a multiorgan and hematological point of view. Aims: To evaluate comprehensive neonatal cardiovascular adaptation during the first days of life with ...
Domenico Antonio Agostino +10 more
doaj +1 more source
Phase-rectified signal averaging method to predict perinatal outcome in infants with very preterm fetal growth restriction- a secondary analysis of TRUFFLE-trial [PDF]
BACKGROUND: Phase-rectified signal averaging, an innovative signal processing technique, can be used to investigate quasi-periodic oscillations in noisy, nonstationary signals that are obtained from fetal heart rate.
Arabin, B +32 more
core
Serum dehydroepiandrosterone sulfate levels and pubarche in short children born small for gestational age before and during growth hormone treatment [PDF]
It has been suggested that the programming of the endocrine axes occurs during critical phases of fetal development and will be affected by intrauterine growth retardation.
Boonstra, V.H. (Venje) +3 more
core +3 more sources
Female sexual maturation and reproduction after prepubertal exposure to estrogens and endocrine disrupting chemicals: A review of rodent and human data [PDF]
Natural hormones and some synthetic chemicals spread into our surrounding environment share the capacity to interact with hormone action and metabolism.
Bourguignon, Jean-Pierre +3 more
core +1 more source
Prenatal and early life influences on epigenetic age in children:a study of mother-offspring pairs from two cohort studies [PDF]
DNA methylation-based biomarkers of aging are highly correlated with actual age. Departures of methylation-estimated age from actual age can be used to define epigenetic measures of child development or age acceleration (AA) in adults.
Gaunt, Tom R +17 more
core +5 more sources
Continuous glucose monitoring in pregnant women with Type 1 diabetes: benefits for mothers, using pumps or pens, and their babies [PDF]
Aims: To review the current literature on the use of continuous glucose monitoring during pregnancy in women with Type 1 diabetes. Methods: We searched the literature for randomized controlled trials using continuous glucose monitoring during pregnancy ...
Feig, Denice S., Murphy, Helen R.
core +1 more source
Background Cardiometabolic risk factors among youth are rising. Epigenetic age acceleration, a biomarker for aging and disease-risk, has been associated with adiposity in children, but its association with other cardiometabolic risk markers remains ...
Jennifer L. Arzu +9 more
doaj +1 more source

