Results 91 to 100 of about 150,377 (309)

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas, Naim Bouazza, Frantz Foissac, Saïk Urien, Léo Froelicher‐Bournaud, Gabrielle Lui, Victoria Guillemart, Nicolas Carlier, Jennifer Da Silva, Johanna Fesenbeckh, Reem Kanaan, Isabelle Honoré, Clémence Martin, Jean‐Marc Treluyer, Vassilis Tsatsaris, Pierre‐Régis Burgel, Sihem Benaboud   +16 more
wiley   +1 more source

Hypertension ın gestational diabetes mellitus: Diagnosıs and treatment

, 2020
Gestational diabetes mellitus and hypertensive disorders of pregnancy, the most common complications in pregnancy, cause short and long term maternal and fetal health problems.
Şişman, Pınar, Gül, Özen Öz
core  

The burden of diabetes mellitus during pregnancy in low- and middle-income countries : a systematic review [PDF]

, 2014
Peer ...
Navya Bezawada, Jacqueline Bell, Lovney Kanguru, Julia Hussein, Hussein, Julia, Bell, Jacqueline, Kanguru, Lovney, Bezawada, Navya   +7 more
core   +1 more source

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

BMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen, Jianfeng Wu, Shunhan Zhang, Siqi Huang, Yingjun Xie, Hongda Chen, Yinghong Yang, Lan Xiao, Ding Wang, Keke Wu, Xiaofang Sun   +10 more
wiley   +1 more source

Placental crises: disruptive selection and maternal under‐investment as the foundations of mammalian placental evolution and dysfunction

Biological Reviews, EarlyView.
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon, Neil J. Gostling, Ian G. Reddin, Bram G. Sengers, Pascale Chavatte‐Palmer, Rohan M. Lewis   +5 more
wiley   +1 more source

Risk Factors for Gestational Diabetes in Pregnant Women: A case-control study

Payesh, 2019
Objective (s): About 90% of diabetes cases during pregnancy are due to gestational diabetes. This study aimed to assess risk factors for gestational diabetes in pregnant women.
Kobra Doostifar, Maryam Parsanahad, Khadijeh Baharzadeh, Fatemeh Khadem, Kambiz AhmadiAngali, Marzieh Araban   +5 more
doaj  

Humans are not unique: difficult birth is common in placental mammals

Biological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

Chronic hypertension with gestational diabetes mellitus: What about complications?

American Journal of Experimental and Clinical Research, 2016
The aim of this study was to evaluate the impact of chronic hypertension and gestational diabetes on pregnancy outcomes. We conducted a historical cohort study of 334 women undergoing singleton births in a Portuguese tertiary care center in Lisbon during
Ana Correia Campos, Ana Catarina Massa, Ricardo Rangel, Manuela Cardoso, Maria Augusta Borges   +4 more
doaj  

Maternal birth weight as an indicator of early and late gestational diabetes mellitus: The Japan Environment and Children's Study

Journal of Diabetes Investigation
Aims This study aimed to investigate the association of maternal birth weight (MBW) with early and late gestational diabetes mellitus (GDM). Methods A total of 69318 pregnant Japanese women were included in this birth cohort study.
Kazuma Tagami, Noriyuki Iwama, Hirotaka Hamada, Hasumi Tomita, Rie Kudo, Natsumi Kumagai, Hongxin Wang, Seiya Izumi, Zen Watanabe, Mami Ishikuro, Taku Obara, Nozomi Tatsuta, Hirohito Metoki, Chiharu Ota, Takashi Sugiyama, Shinichi Kuriyama, Takahiro Arima, Nobuo Yaegashi, Masatoshi Saito, The Japan Environment and Children's Study Group   +19 more
doaj   +1 more source