Results 81 to 90 of about 240,504 (297)

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

BMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen, Jianfeng Wu, Shunhan Zhang, Siqi Huang, Yingjun Xie, Hongda Chen, Yinghong Yang, Lan Xiao, Ding Wang, Keke Wu, Xiaofang Sun   +10 more
wiley   +1 more source

PATHOPHYSIOLOGY OF GESTATIONAL DIABETES MELLITUS

European Medical Journal Diabetes, 2019
Gestational diabetes mellitus (GDM) is a pregnancy complication defined as a glucose intolerance of varying severity with onset or first recognition during pregnancy. The prevalence of GDM is growing rapidly worldwide.
Zehra Berberoglu
doaj  

Effect of gestational diabetes on purkinje and granule cells distribution of the rat cerebellum in 21 and 28 days of postnatal life [PDF]

, 2015
Introduction: Diabetes mellitus is associated with nervous system alterations in both human and animal models. This study was done to determine the effect of gestational diabetes on the Purkinje and granular cells in the cerebellum of rat offspring ...
Ghafari, S., Golalipour, M.J., Razi, E.M.   +2 more
core   +1 more source

Placental crises: disruptive selection and maternal under‐investment as the foundations of mammalian placental evolution and dysfunction

Biological Reviews, EarlyView.
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon, Neil J. Gostling, Ian G. Reddin, Bram G. Sengers, Pascale Chavatte‐Palmer, Rohan M. Lewis   +5 more
wiley   +1 more source

Gestational Diabetes

Obstetrics, Gynaecology & Reproductive Medicine, 2014
Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance resulting in hyperglycaemia of variable severity with onset or first recognition during pregnancy. It is a common condition and is associated with increased risk of perinatal complications.
Hunt, Katharine F., Whitelaw, Ben, Gayle, Carol   +2 more
openaire   +3 more sources

Birthweight and risk markers for type 2 diabetes and cardiovascular disease in childhood: the Child Heart and Health Study in England (CHASE). [PDF]

, 2015
AIMS/HYPOTHESIS: Lower birthweight (a marker of fetal undernutrition) is associated with higher risks of type 2 diabetes and cardiovascular disease (CVD) and could explain ethnic differences in these diseases. We examined associations between birthweight
A Bavdekar, A Lucas, Alicja R. Rudnicka, Angela S. Donin, AS Donin, AS Donin, B Park, BJ McNamara, C Li, C Thomas, Cathy M. McKay, CG Owen, Christopher G. Owen, Claire M. Nightingale, CM Law, CM Nightingale, CM Nightingale, CS Yajnik, DA Lawlor, Debbie A. Lawlor, Derek G. Cook, DJ Barker, DL Kuh, F Mzayek, GV Krishnaveni, I Shai, J West, JC Levy, Jennifer L. Bales, MC Franco, MR Skilton, Naveed Sattar, Office for National Statistics, P Fossati, Peter H. Whincup, PH Whincup, PH Whincup, PH Whincup, PH Whincup, PH Whincup, Phillip J. Steer, R Huxley, R Huxley, R Huxley, R Pfister, RS Bhopal, S Kodama, SH Wild, Sian L. Newton, SM Sayers, T Kaneshi, WB White, YK Tu   +52 more
core   +2 more sources

Humans are not unique: difficult birth is common in placental mammals

Biological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

Editorial: The origin and establishment process of gut microbiota in early life

Frontiers in Microbiology, 2023
Yu Liu, Yu Liu, Huixia Yang, Huixia Yang
doaj   +1 more source

Gestational Diabetes as a Predictor of Sexual Dysfunction in Pregnant Women

Journal of Holistic Nursing and Midwifery, 2021
Introduction: Pregnancy is associated with changes in sexual function and perhaps many more sexual problems when accompanied by particular disorders such as gestational diabetes.
Ommolbanin Zare, Masoumeh Simbar, Giti Ozgoli, Adeleh Bahar, Hamid Alavi Majd   +4 more
doaj  

Caesarean section and risk of unexplained stillbirth in subsequent pregnancy [PDF]

, 2003
Background Caesarean section is associated with an increased risk of disorders of placentation in subsequent pregnancies, but effects on the rate of antepartum stillbirth are unknown.
Alfirevic, Ananth, Campbell, Castro, Cnattingius, Cole, Cole, Feldman, Gordon CS Smith, Grambsch, Hannah, Hemminki, Hosmer, Jensen, Jill P Pell, Kendrick, Kingdom, Lees, Lieberman, Lydon-Rochelle, Lydon-Rochelle, Macara, Mailer, McIlwaine, McLoone, Moore, Morrison, Parrish, Pocock, Porreco, Rasmussen, Richard Bobbie, Smith, Smith, Soper, Thorpe-Beeston, Yudkin   +36 more
core   +1 more source