Results 51 to 60 of about 1,321,162 (305)

Centers for Disease Control and Prevention–Recognized Diabetes Prevention Program After Gestational Diabetes Mellitus

open access: yesAJOG Global Reports, 2023
Gestational diabetes mellitus is associated with an increased risk of developing type 2 diabetes mellitus. To decrease or delay the risk of developing type 2 diabetes mellitus after gestational diabetes mellitus, postpartum care should include a ...
Cassandra E. Henderson, MD   +2 more
doaj   +1 more source

Incident Comorbid Diabetes and Outcomes in Multiple Sclerosis: An English Population‐Based Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the incidence of diabetes mellitus and its associations with hospitalisation and mortality in adults with multiple sclerosis (MS) and matched controls. Methods Using English primary care data from the Clinical Practice Research Datalink, linked to hospital and mortality records, we matched adults with MS with up to 10 ...
Yolanda Lau   +8 more
wiley   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

open access: yesAdvanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang   +18 more
wiley   +1 more source

Frequency of Gestational Diabetes Mellitus in Pregnant Women Reporting to a Public Sector Tertiary Care Hospital of Quetta

open access: yesPakistan Armed Forces Medical Journal, 2022
Objective: To determine the frequency of gestational diabetes mellitus in pregnant women reporting to a public sector tertiary care hospital and find the association of gestational diabetes mellitus with age. Study Design: Comparative cross-sectional
Majid Latif   +6 more
doaj   +1 more source

Maternal Hyperglycemia Disrupts Cerebral Cortex Development Through the Foxp1‐Dll1‐Notch Axis

open access: yesAdvanced Science, EarlyView.
Maternal hyperglycemia disrupts offspring cortical development through a Foxp1–Dll1–Notch signaling axis. In a PGDM mouse model, intrauterine hyperglycemia decreases cortical thickness and perturbs neuronal layering by downregulating Foxp1, which transcriptionally regulates the Notch ligand Dll1.
Longkai He   +12 more
wiley   +1 more source

Biallelic PAX6 Variants in an Adult With Severe Microphthalmia and Preserved Intellectual Function

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT PAX6 encodes a dosage‐sensitive transcription factor that is essential for eye development. Heterozygous PAX6 disease is well characterized, but biallelic disease is extremely rare and has been associated with anophthalmia, severe brain malformations, and perinatal lethality.
Karl De Geer   +4 more
wiley   +1 more source

Effects of gestational diabetes mellitus on risk of adverse maternal outcomes: a prospective cohort study in Northwest Ethiopia

open access: yesBMC Pregnancy and Childbirth, 2020
Background Gestational diabetes mellitus is a leading medical condition woman encounter during pregnancy with serious short- and long-term consequences for maternal morbidity.
Achenef Asmamaw Muche   +2 more
doaj   +1 more source

Recent Advances in Gestational Diabetes Mellitus [PDF]

open access: yes, 2021
The incidence of gestational diabetes mellitus (GDM) and overt diabetes in pregnancy is rising globally [...].status ...
Benhalima, Katrien, Katrien Benhalima
core   +1 more source

British National Formulary Guidance on prescribing in pregnancy: A descriptive cross‐sectional study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To assess how well pregnancy‐specific guidance within the British National Formulary supports healthcare professionals to facilitate safe and effective medication use. Methods We performed a manifest content analysis of the text of all pregnancy sections within British National Formulary drug monographs, with inductive and iterative coding.
Hannah Johnson   +9 more
wiley   +1 more source

Proteomic Profiling of Xenobiotic and Nutrient Transporters in Human Placenta of Different Gestational Ages

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The placenta serves a critical role in nutrient uptake and waste elimination for the developing fetus. The placenta is also responsible for the uptake and/or exchange of xenobiotics, including medications, between the maternal and fetal bloodstreams. An estimated 40–80% of women take medications or drugs during pregnancy.
Eric M. Weaver   +6 more
wiley   +1 more source

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