Results 41 to 50 of about 14,312 (250)

A Practical Understanding of Preeclampsia for a Nurse in a Third World Setting [PDF]

open access: yes, 2019
Preeclampsia is a disease of pregnancy that affects approximately 3-5% of women with child. It is one of the primary causes of mortality in mothers and babies across the globe. The exact cause, pathogenesis, or disease progression is unknown.
Lovin, Anna
core   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu   +10 more
wiley   +1 more source

Endocervical Placental Site Trophoblastic Tumor: A Case Report

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2004
Objective: We report the treatment of a patient with persistent gestational trophoblastic disease. Case Report: A 42-year-old woman, gravida 2, para 1, was initially diagnosed with choriocarcinoma from curettage specimens.
Yiu-Tai Li   +3 more
doaj   +1 more source

Placental site trophoblastic tumor: a case report and review of the literature [PDF]

open access: yes, 2015
We present a case of a gravida 1 para 1 woman, who presented with an 11- month history of amenorrhea after cesarean delivery. The patient was taking birth control pills at the time of presentation.
Cunha, Teresa Margarida   +2 more
core   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

open access: yesAdvanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen   +11 more
wiley   +1 more source

Cross Sectional Study: A Five Year Review Of Gestational Trophoblastic Disease In Kuantan General Hospital (Jan 1995 - Dec 1999) [PDF]

open access: yes, 2001
To study the epidemiology, features, treatment of Gestational Trophoblastic Disease (GTD) and regression of serum BheG in Hydatidiform mole. To identify factors that predict the risk of developing Gestational Trophoblastic Tumour (GTT) from Hydatidiform ...
Mohamed Jamli, Mohamad Faiz
core   +1 more source

Term delivery choriocarcinoma patient with brain and lung metastases successfully treated by etoposide, methotrexate, actomycin D, cyclophosphamide and vincristine (EMA-CO) chemotherapy. [PDF]

open access: yes, 2005
It is well known that antecedent term delivery and metastasis to sites other than the lungs and vagina are high risk factors for patients with gestational trophoblastic neoplasia.
Hiramatsu, Yuji   +4 more
core   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

open access: yesAdvanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She   +14 more
wiley   +1 more source

Gestational Trophoblastic Disease

open access: yesRevisiones en Cáncer
Bruce S, Sorosky J.
europepmc   +3 more sources

Comparing and Evaluating Five-Day Chemotherapy Agents Actinomycin D and Methotrexate in Low-Risk Post-Molar Gestational Trophoblastic Neoplasia: A Retrospective Analysis

open access: yesClinical and Experimental Obstetrics & Gynecology, 2022
Background: Low-risk post-molar gestational trophoblastic neoplasia is sensitive to chemotherapy, but there is no consensus regarding the best treatment regimen for low-risk post-molar gestational trophoblastic neoplasia.
Juan Xu, Xinmei Wang, Pengpeng Qu
doaj   +1 more source

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