Results 41 to 50 of about 7,331 (186)

Placental site trophoblastic tumor

Frontiers in Surgery, 2014
Trophoblastic tumors of placental site (PSTT) are rare. They represent a rare form of gestational trophoblastic disease. (GTD). They occur mainly in women who have a history of miscarriage, termination of pregnancy, or even a normal or pathological ...
Jean eBouquet De Jolinière
doaj   +1 more source

MR“I”: An “eye” for the preoperative diagnosis of ectopic molar pregnancy, a case report

Journal of Family Medicine and Primary Care, 2023
Hydatidiform mole (complete and partial), invasive mole, choriocarcinoma, placental site trophoblastic disease, and epithelioid trophoblastic tumour constitute the spectrum of benign and malignant gestational trophoblastic disease[1] Invasive mole ...
Sujith Rajashekar Swamy, Meghana Rajashekara Swamy, H. Samanvitha, Sara Elsayed   +3 more
doaj   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Is Doppler ultrasound useful for evaluating gestational trophoblastic disease?

Clinics
Doppler ultrasound is a non-invasive method for evaluating vascularization and is widely used in clinical practice. Gestational trophoblastic neoplasia includes a group of highly vascularized malignancies derived from placental cells.
Lawrence H. Lin, Lisandra S. Bernardes, Eliane A. Hase, Koji Fushida, Rossana P.V. Francisco   +4 more
doaj   +1 more source

Gestational Trophoblastic Disease: A Multimodality Imaging Approach with Impact on Diagnosis and Management

Radiology Research and Practice, 2014
Gestational trophoblastic disease is a condition of uncertain etiology, comprised of hydatiform mole (complete and partial), invasive mole, choriocarcinoma, and placental site trophoblastic tumor.
Sunita Dhanda, Subhash Ramani, Meenkashi Thakur   +2 more
doaj   +1 more source

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

Advanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang, Shaoju Jin, Shaoying Wen, Wen Zeng, Chen Wang, Jingyu Wang, Qingyun Song, Guizhong Li, Pengzhi Yin, Yuhui Liao, Yuee Chai, Huiping Zhang, Shengchao Ma   +12 more
wiley   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Recurrent pneumothoraces caused by a high-grade lung carcinoma with trophoblastic differentiation: a case report

Frontiers in Oncology
Gestational trophoblastic neoplasms are tumors that occur during pregnancy, while non-gestational trophoblastic tumors have a similar histology but are present outside of gestation. Literature reports several cases of non-gestational trophoblastic tumors
Márton Csaba, Márton Csaba, Zsolt Megyesfalvi, Zsolt Megyesfalvi, László Báthory-Fülöp, Tamás Pintér, László Agócs, László Agócs, László Agócs, Balázs Döme, Balázs Döme, Balázs Döme, Ferenc Rényi-Vámos, Ferenc Rényi-Vámos, Ferenc Rényi-Vámos, Ferenc Rényi-Vámos, Áron Kristóf Ghimessy, Áron Kristóf Ghimessy   +17 more
doaj   +1 more source

Placental crises: disruptive selection and maternal under‐investment as the foundations of mammalian placental evolution and dysfunction

Biological Reviews, EarlyView.
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon, Neil J. Gostling, Ian G. Reddin, Bram G. Sengers, Pascale Chavatte‐Palmer, Rohan M. Lewis   +5 more
wiley   +1 more source

Delivery of Euthyroid Baby following Hyperthyroidism in Twin Gestation with Coexisting Complete Hydatidiform Mole

Case Reports in Endocrinology, 2019
Context. Gestational trophoblastic disease (GTD) is a rare complication of pregnancy, ranging from molar pregnancy to choriocarcinoma. Twin pregnancies with GTD and coexisting normal fetus are extremely rare with an estimated incidence of 1 case per 22 ...
Rishi Raj, Edilfavia Mae Uy, Matthew Hager, Kamyar Asadipooya   +3 more
doaj   +1 more source