Results 41 to 50 of about 5,004,763 (240)

P63 expression in gestational trophoblastic disease: Correlation with proliferation and apoptotic dynamics

open access: yes, 2009
p63 regulates cell growth and differentiation and contributes to tumorigenesis through its complex isoforms. Gestational trophoblastic disease encompasses a heterogeneous family of lesions with different malignant potential that arise from various ...
Hextan Yuen-Sheung Ngan   +17 more
core   +1 more source

Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance

open access: yesAdvanced Science, EarlyView.
COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu   +12 more
wiley   +1 more source

Effect of race/ethnicity on clinical presentation and risk of gestational trophoblastic neoplasia in patients with complete and partial molar pregnancy at a tertiary care referral center

open access: yes, 2016
BACKGROUND: The reported incidence of molar pregnancy varies widely among different geographic locations. This variation has been attributed, at least in part, to racial/ethnic differences.
Gockley, Allison A.   +8 more
core   +1 more source

Endocervical Placental Site Trophoblastic Tumor: A Case Report

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2004
Objective: We report the treatment of a patient with persistent gestational trophoblastic disease. Case Report: A 42-year-old woman, gravida 2, para 1, was initially diagnosed with choriocarcinoma from curettage specimens.
Yiu-Tai Li   +3 more
doaj   +1 more source

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung   +12 more
wiley   +1 more source

Gestational trophoblastic disease: Literature review

open access: yes, 2011
Gestational trophoblastic disease is characterized by abnormal proliferation of pregnancy-associated trophoblastic tissue with malignant potential.
Biljana Lazovic, Vera Milenkovic
core   +1 more source

GESTATIONAL TROPHOBLASTIC DISEASE IN BASRAH [PDF]

open access: yesThe Medical Journal of Basrah University, 2007
To date few studies have been reported from Basrah regarding Gestational Trophoblastic disease GTD. This study was a clinical observational study done in Basrah at the 4 main obstetric hospitals based on 137 patients with GTD.
Hassna M. Chaied, Zaineb .T. AL Yasin
doaj   +1 more source

Placental-site trophoblastic tumor with bone metastasis: A diagnostic and therapeutic challenge

open access: yesGynecologic Oncology Reports, 2023
Placental-site trophoblastic tumor (PSTT) is a rare pathological entity included in the spectrum of gestational trophoblastic neoplasia (GTN). It is a neoplasia with metastatic potential that, once metastasized, has poor prognosis because the tumor tends
Alfredo Ramirez-Espinoza   +5 more
doaj   +1 more source

Advancing Pregnancy and Pediatric Science through the NIH Transporter Elucidation Network

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Human gestation is characterized by dynamic changes in maternal physiology and maturation of tissue functions before and after birth. The fetus and neonate are highly dependent upon transfer of maternal nutrients via the placenta and lactating mammary gland, which frequently involve selective membrane transporter proteins.
Joanne Wang   +16 more
wiley   +1 more source

Overexpression of NANOG in gestational trophoblastic diseases: Effect on apoptosis, cell invasion, and clinical outcome

open access: yes, 2008
Gestational trophoblastic disease includes choriocarcinoma, a frankly malignant tumor, and hydatidiform mole (HM), which often leads to the development of persistent gestational trophoblastic neoplasia and requires chemotherapy.
Wong, ESY   +5 more
core   +1 more source

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