Results 61 to 70 of about 32,157 (262)

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Temporal relationships between speech and hand gestures in the vicinity of potential turn boundaries in German and Swedish conversation

open access: yesLanguage and Cognition
Both gesture and talk are basic building blocks of face-to-face conversation. In this study, we address the temporal dynamics of hand gesture phases relative to places and types of turn transition.
Margaret Zellers   +2 more
doaj   +1 more source

An Intelligent Gesture Classification Model for Domestic Wheelchair Navigation with Gesture Variance Compensation

open access: yesApplied Bionics and Biomechanics, 2020
Elderly and disabled population is rapidly increasing. It is important to uplift their living standards by improving the confidence towards daily activities.
H. M. Ravindu T. Bandara   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Design of Human–Computer Interaction Gesture Tracking Model Based on Improved PSO and KCF Algorithms

open access: yesIEEE Access
The detection and tracking of gesture targets is an important aspect in the dynamic gesture recognition. To meet the accuracy and speed requirements of human-computer interaction for dynamic gesture recognition, this study explores long-term gesture ...
Dinghua He, Yan Yang, Rangzhong Wu
doaj   +1 more source

Combined Hand Gesture — Speech Model for Human Action Recognition

open access: yesSensors, 2013
This study proposes a dynamic hand gesture detection technology to effectively detect dynamic hand gesture areas, and a hand gesture recognition technology to improve the dynamic hand gesture recognition rate.
Sheng-Tzong Cheng   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Gesture-based target acquisition in virtual and augmented reality

open access: yesVirtual Reality & Intelligent Hardware, 2019
Background Gesture is a basic interaction channel that is frequently used by humans to communicate in daily life. In this paper, we explore to use gesture-based approaches for target acquisition in virtual and augmented reality.
Yukang YAN   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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