Results 211 to 220 of about 158,206 (306)

Increased expression of inflammasome signaling genes and proteins in selective brain regions in the intermediate stage of Alzheimer's disease

open access: yesBrain Pathology, EarlyView.
Neuritic plaques increase in the intermediate stage of Alzheimer's neuropathological change. The intermediate stage of Alzheimer's disease was investigated by transcriptomics and immunohistochemistry. This revealed that inflammasome sensors NLRP1, NLRP3, and AIM2 oligomerize with ASC speck to form the inflammasome complex and initiate the downstream ...
Juan Pablo de Rivero Vaccari   +10 more
wiley   +1 more source

Exploratory study of plasma GFAP and GAD65-Ab levels in children with ADHD. [PDF]

open access: yesItal J Pediatr
Li RL   +11 more
europepmc   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

open access: yesBrain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira   +19 more
wiley   +1 more source

Alexander disease mutations differentially sensitize glial fibrillary acidic protein (GFAP) to posttranslational modifications and network disruption by oxidants. [PDF]

open access: yesRedox Biol
Goya-Iglesias N   +7 more
europepmc   +1 more source

Clinical and molecular features of primary gliosarcoma with digital spatial whole‐transcriptome analysis of glial and mesenchymal components

open access: yesBrain Pathology, EarlyView.
We report the clinical and genetic features of an institutional cohort of primary adult gliosarcomas compared to glioblastoma. We performed spatial whole‐transcriptome analysis on glial and sarcomatous regions of four cases to compare gene expression profiles and validated differential protein expression for two markers in tissue sections.
Matthew D. Wood   +6 more
wiley   +1 more source

Running Exercise Promotes Astrocyte-Mediated Structural Plasticity in the Amygdalar BLA and CeA to Alleviate Anhedonia-like Behavior Alterations. [PDF]

open access: yesCells
Ren X   +17 more
europepmc   +1 more source

Dulaglutide and neurodegeneration biomarkers: REWIND post hoc analysis. [PDF]

open access: yesAlzheimers Dement
Wilson JM   +9 more
europepmc   +1 more source

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