Results 191 to 200 of about 127,947 (249)

Ascorbic Acid Neuroprotection Against Hippocampal Injury and Gliosis Induced by E621 in Albino Rats Through Modulation of GFAP, Synaptophysin, and Caspase-3 [PDF]

Enas N. Morgan, Ayman Mousa, Rasha A. Elmansy, Hanan S. Seleem, Marwa M Fawzi, Amany Refaat Mahmoud, Reham Abdulla Aboukhalil, Hagir H. T. Ahmed, Reem A. Younis, Tarek Hamdy Abd‐Elhamid, Asmaa Jabeen, Ashwag Saleh Alsharidah, Samah Mohammed Mahmoud Abozaid, Abdullah M. Alnuqaydan, Khaled E. A. Soliman, Enas Haridy Ahmed   +15 more
openalex   +1 more source

The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity

Epilepsia Open, EarlyView.
Abstract Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network‐level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare
Mohammad Reza Seyedtaghia, Jina Babanzadeh, Marcello Scala, Lorenzo Perilli, Pasquale Striano   +4 more
wiley   +1 more source

Primary Cilia of Astrocytes in the Retina in Development and Disease. [PDF]

Invest Ophthalmol Vis Sci
Ning K, Tran M, Xia X, Kowal TJ, Wang Q, Lo CH, Chen S, Liu Z, Li T, Zhang F, Wang W, Sun Y.   +11 more
europepmc   +1 more source

Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP)

I. Yu. Oganesyan, S. A. Dzhukkaeva, Sh. R. Nabiev, Olga N. Voskresenskaya   +3 more
openalex   +2 more sources

Astrocyte subtype‐specific alterations in the dentate gyrus of individuals with mesial temporal lobe epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy affects approximately 50 million people worldwide and, although primarily attributed to neuronal dysfunction, increasing evidence highlights a critical role of glial cells, particularly astrocytes, in the pathophysiological mechanisms.
Chiara Lötzsch, Jakob Johann Schmidt, Daniel Delev, Roland Coras, Ingmar Blümcke, Ruth Beckervordersandforth   +5 more
wiley   +1 more source

Collagen-induced restructuring of astrocytes and vessels in organotypic mouse brain slices. [PDF]

Front Aging
Steiner E, Wolfgang V, Humpel C.
europepmc   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Blood-based biomarkers of Alzheimer's disease and neurodegeneration in an indigenous African cohort using both Simoa and NULISA platforms. [PDF]

NPJ Dement
Akinyemi T, Pola I, Tan K, Olalusi O, Yaria J, Ogunde G, Traichel W, Rahmouni N, Oguntiloye O, Fagbemi A, Cadmus E, Popoola F, Therriault J, Ogunronbi M, Olujobi D, Famuyiwa O, Akinyemi J, Pascoal T, Owolabi M, Rosa-Neto P, Udeh-Momoh CT, Ladokun O, Romero-Ortuno R, Ogunniyi A, Lawlor B, Kalaria R, Zetterberg H, Benedet AL, Akinyemi R.   +28 more
europepmc   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source

Cerebral Herniation and Sudden Death in Autoimmune Glial Fibrillary Acidic Protein (GFAP) Astrocytopathy: A Case Report

Bishow C. Mahat, Mohamed Fahmy Doheim, Lamees Alzyoud, Katharine Dermigny, Islam Zaydan, Rock Heyman, Madison Pilato   +6 more
openalex   +2 more sources