Results 201 to 210 of about 43,755 (242)
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Current Biology, 2023
López and Nogueiras introduce the peptide ghrelin and its physiological functions, including its roles in stimulating appetite and growth hormone release.
Miguel, López, Ruben, Nogueiras
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López and Nogueiras introduce the peptide ghrelin and its physiological functions, including its roles in stimulating appetite and growth hormone release.
Miguel, López, Ruben, Nogueiras
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The Role of Ghrelin and Ghrelin Signaling in Aging [PDF]
International Journal of Molecular Sciences, 2017 With our aging society, more people hope for a long and healthy life. In recent years, researchers have focused on healthy longevity factors. In particular, calorie restriction delays aging, reduces mortality, and extends life. Ghrelin, which is secreted during fasting, is well known as an orexigenic peptide.
Marie Amitani +2 more
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Metabolic Syndrome and Related Disorders, 2006
Ghrelin was discovered for its ability to bind the growth hormone secretagogue receptor (GHSR1a) and stimulate growth hormone release. However, much research conducted with this novel stomach hormone is focused on proposed roles for it to participate in regulating energy balance.
Mark L, Heiman, Derrick R, Witcher
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Ghrelin was discovered for its ability to bind the growth hormone secretagogue receptor (GHSR1a) and stimulate growth hormone release. However, much research conducted with this novel stomach hormone is focused on proposed roles for it to participate in regulating energy balance.
Mark L, Heiman, Derrick R, Witcher
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Peptides, 2019
Ghrelin, a growth hormone-releasing peptide that was first discovered in the stomach of rats in 1999, is an endogenous ligand of growth hormone secretagogue receptor. Ghrelin exerts its potent growth hormone-releasing and orexigenic activities by binding to specific receptors in the brain.
Takeshi Tokudome +3 more
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Ghrelin, a growth hormone-releasing peptide that was first discovered in the stomach of rats in 1999, is an endogenous ligand of growth hormone secretagogue receptor. Ghrelin exerts its potent growth hormone-releasing and orexigenic activities by binding to specific receptors in the brain.
Takeshi Tokudome +3 more
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BioFactors, 2013
AbstractGhrelin is a gut‐derived peptide hormone, first isolated from the stomach. Ghrelin was initially characterized as a growth hormone (GH) secretagogue, but it plays a more important role as a potent orexigen and modulator of whole‐body energy homeostasis. Ghrelin itself is closely regulated by metabolic status.
Patric J D, Delhanty +2 more
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AbstractGhrelin is a gut‐derived peptide hormone, first isolated from the stomach. Ghrelin was initially characterized as a growth hormone (GH) secretagogue, but it plays a more important role as a potent orexigen and modulator of whole‐body energy homeostasis. Ghrelin itself is closely regulated by metabolic status.
Patric J D, Delhanty +2 more
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Current Opinion in Clinical Nutrition & Metabolic Care, 2017
A compromised autophagy is associated with the onset of obesity, type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular and neurodegenerative diseases. Our aim is to review the potential role of ghrelin, a gut hormone involved in energy homeostasis, in the regulation of autophagy.In the recent years, it has been demonstrated that autophagy ...
Silvia, Ezquerro +2 more
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A compromised autophagy is associated with the onset of obesity, type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular and neurodegenerative diseases. Our aim is to review the potential role of ghrelin, a gut hormone involved in energy homeostasis, in the regulation of autophagy.In the recent years, it has been demonstrated that autophagy ...
Silvia, Ezquerro +2 more
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Current Opinion in Lipidology, 2015
The increasing prevalence of metabolic syndrome and the consequent cardiovascular diseases has stimulated an active search for novel risk factors. The hormones regulating energy balance are of special interest as potential risk factor indicators of cardiovascular diseases.
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The increasing prevalence of metabolic syndrome and the consequent cardiovascular diseases has stimulated an active search for novel risk factors. The hormones regulating energy balance are of special interest as potential risk factor indicators of cardiovascular diseases.
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2013
Since the original discovery of ghrelin and, subsequently, obestatin (the alternative product of the ghrelin gene), a major interest has been devoted to the investigation of their central and peripheral activities in physiological conditions as well as on their role in metabolic diseases.
Mauro, Papotti +2 more
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Since the original discovery of ghrelin and, subsequently, obestatin (the alternative product of the ghrelin gene), a major interest has been devoted to the investigation of their central and peripheral activities in physiological conditions as well as on their role in metabolic diseases.
Mauro, Papotti +2 more
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2007
A consequence of gastrectomy is loss of bone mass. Several mechanisms have been proposed, such as malabsorption of vitamins and minerals. Additionally, a peptide hormone produced in the stomach has been shown to mediate a calcitropic effect on bone.
van der Velde, Martijn +4 more
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A consequence of gastrectomy is loss of bone mass. Several mechanisms have been proposed, such as malabsorption of vitamins and minerals. Additionally, a peptide hormone produced in the stomach has been shown to mediate a calcitropic effect on bone.
van der Velde, Martijn +4 more
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The role of ghrelin and ghrelin analogues in wasting disease
Current Opinion in Clinical Nutrition and Metabolic Care, 2008The purpose of this review is to summarize recent studies that investigated the role of ghrelin and ghrelin analogs in wasting conditions.Numerous studies have demonstrated potential beneficial effects exerted by ghrelin in a number of diseases associated with wasting.
Mayra M, Kamiji, Akio, Inui
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