Results 271 to 280 of about 76,458 (284)
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Ghrelin

2016
Ghrelin (GHRL) was first discovered as a growth hormone secretagog secreted from the stomach, and showed a novel regulatory pathway for GH secretion. In addition to this, feeding-stimulatory activity is expected from the production site in the arcuate nuclei of the hypothalamus, and it is now recognized as the only hormone to stimulate food intake ...
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The Structure of Ghrelin

2007
The structure of ghrelin, a 28-residue octanoylated peptide hormone, is only known up to the level of primary structure identifying an active core of residues 1-5 or 1-4 including octanoyl-Ser3 as necessary to elicit receptor response. This chapter reviews the results and limitations of experimental and computer modeling studies, which have appeared in
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Ghrelin

2009
Ghrelin, öncelikli olarak midedeki endokrin X(A) hücreleri tarafından salgılanan polipeptid yapıda bir hormondur. Ghrelin, büyüme hormonunun salınımı, enerji dengesi, besin alımı ve vücut ağırlığının ayarlanmasında görev alır. 28 aminoasitten oluşan moleküler yapısında, 3.
İLHAN, Tuncay, ERDOST, Hatice
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Transgenic Mice Overexpressing Ghrelin or Ghrelin Analog

2012
To understand the chronic effects of ghrelin, genetically engineered mouse models would be useful. Early studies, however, suggested that it was challenging to generate ghrelin gain-of-activity models by standard procedures. Although several groups have been trying to generate transgenic (Tg) mice overexpressing ghrelin, almost all these animals ...
Hiroshi Iwakura   +6 more
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Ghrelin and Prostate Cancer

2007
Ghrelin, a 28-amino acid octanoylated peptide predominantly produced by the stomach, has been discovered to be a natural ligand of the type 1a growth hormone secretagogue receptor (GHSR1a). Ghrelin has recently attracted the interest as a new GH-releasing and orexigenic factor.
LANFRANCO, Fabio   +5 more
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Structure and Function of Ghrelin

2008
The endogenous ligand for growth-hormone secretagogue receptor (GHS-R) was purified from the stomach and we named it "ghrelin", after a word root ("ghre") in Proto-Indo-European languages meaning "grow", since ghrelin has potent growth hormone (GH) releasing activity.
Masayasu Kojima, Kenji Kangawa
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Assessment of ghrelin.

APMIS. Supplementum, 2003
Four years ago Kojima and coworkers discovered ghrelin. Within this short lifespan ghrelin has become one of the "hottest topics" in metabolic research, and today more than 300 papers have emerged (PubMed search). The huge interest in ghrelin is partly due to its involvement in appetite regulation.
Espelund, Ulrick   +3 more
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Ghrelin

Trends in Endocrinology & Metabolism
Maria E R, Garcia-Rendueles   +2 more
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Ghrelin

2020
Annamaria Colao   +2 more
openaire   +1 more source

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