Results 51 to 60 of about 483,563 (314)

Multi-Omics Characterization of Peripheral Blood Molecular Profiles in Hypertensive Aging Ailuropoda melanoleuca with Levamlodipine Intervention: Exploratory Analysis of ACE2 and Time-Resolved Transcriptomic Patterns

Animals
Hypertension threatens the health of aging captive giant pandas, yet its molecular signatures remain poorly characterized. Here, multi-omics sequencing was applied to explore the molecular regulatory process of hypertension and the pharmacodynamic effect
Yan Zhu, Qian Tao, Chengyao Li, Shanshan Ling, Ming Wei, Mengfang Yang, Danyu Chen, Desheng Li, Caiwu Li, Chengdong Wang   +9 more
doaj   +1 more source

Antimicrobial resistance of Escherichia coli, Enterobacter spp., Klebsiella pneumoniae and Enterococcus spp. isolated from the feces of giant panda

BMC Microbiology, 2022
Background Escherichia coli, Enterobacter spp., Klebsiella pneumoniae and Enterococcus spp., common gut bacteria in giant pandas, include opportunistic pathogens.
Xin Wang, Yi Zhang, Caiwu Li, Guo Li, Daifu Wu, Ti Li, Yuanyuan Qu, Wenwen Deng, Yongguo He, Petri Penttinen, Hemin Zhang, Yan Huang, Ke Zhao, Likou Zou   +13 more
doaj   +1 more source

High Prevalence of Antimicrobial Resistance and Integron Gene Cassettes in Multi-Drug-Resistant Klebsiella pneumoniae Isolates From Captive Giant Pandas (Ailuropoda melanoleuca)

Frontiers in Microbiology, 2022
Multi-drug-resistant Klebsiella pneumoniae (MDR K. pneumonia) is increasingly being reported with corresponding increase in morbidity and mortality all over the world. However, limited information is available concerning MDR K. pneumonia in giant pandas.
Xia Yan, Xia Yan, Xiaoyan Su, Zhihua Ren, Xueyang Fan, Yunli Li, Chanjuan Yue, Mei Yang, Huidan Deng, Youtian Deng, Zhiwen Xu, Dongsheng Zhang, Lin Li, Rong Hou, Songrui Liu, Junliang Deng   +15 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Unique occurrence of trichilemmal carcinoma in the scrotal skin of a giant panda: a pathological analysis

BMC Veterinary Research
Background Trichilemmal carcinoma (TC) is a rare cutaneous appendage malignancy with scarce human cases and very few animal cases have been documented in the available literature, especially in giant pandas.
Chengyao Li, Zongliang Xiong, Shanshan Ling, Yan Zhu, Linhua Deng, Mengfang Yang, Chengdong Wang, Qian Wang, Danyu Chen, Mao Huang, Kao Wang, Desheng Li, Zhengli Chen, Caiwu Li   +13 more
doaj   +1 more source

Observing giant panda habitat and forage abundance from space [PDF]

, 2009
Giant pandas are obligate bamboo grazers. The bamboos favoured by giant pandas are typical forest understorey plants. Therefore, the availability and abundance of understorey bamboo is a key factor in determining the quantity and quality of giant ...
Wang, T.
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Giants on and about Giants

MGIMO Review of International Relations, 2011
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openaire   +3 more sources

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source