Results 61 to 70 of about 23,339 (211)
Shoulder pain due to cervical radiculopathy: an underestimated long-term complication of herpes zoster virus reactivation? [PDF]
, 2018 Purpose To evaluate if herpes zoster virus (HZV) reactivation may be considered in the aetiology of cervical radiculopathy. Methods The study group was composed of 110 patients (52 M-58F;mean age ± SD:46.5 ± 6.12; range:40-73) with a clinical ...
AS Hilibrand +34 more
core +1 more source
The impact of systemic long‐term medications for the development of age‐related macular degeneration
Acta Ophthalmologica, EarlyView.Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä +3 more
wiley +1 more source
A genome-wide association study identifies risk alleles in plasminogen and P4HA2 associated with giant cell arteritis [PDF]
, 2016 Giant cell arteritis (GCA) is the most common form of vasculitis in individuals older than 50 years in Western countries. To shed light onto the genetic background influencing susceptibility for GCA, we performed a genome-wide association screening in a ...
Abdel Salih +183 more
core +9 more sources
A Case of Sixth Cranial Nerve Palsy and Suspected Giant Cell Arteritis [PDF]
, 2017 Sudden onset of horizontal diplopia in an elderly patient can be due to giant cell arteritis. Although the patient reported was a vasculopath, a concurrent headache, mild reduction in visual acuity, scalp tenderness and raised inflammatory markers lead ...
D'Ath, P., Wilson, C. M.
core
PTPN22 gene polymorphism in Takayasu's arteritis [PDF]
, 2008 Objective. Takayasu's arteritis (TA) is a chronic, rare granulomatous panarteritis of unknown aetiology involving mainly the aorta and its major branches.
Akar, S. +18 more
core +2 more sources
Acta Ophthalmologica, EarlyView.Abstract Purpose To investigate the diagnostic performance of ultrasound, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose positron emission tomography/computed tomography (2‐[18F]FDG PET/CT) and temporal artery biopsy (TAB) in giant cell arteritis (GCA). Methods This was a prospective single‐centre diagnostic accuracy study (ClinicalTrials.gov NCT05248906).
Michael S. Hansen +10 more
wiley +1 more source
Giant Cell Arteritis: A Diagnostic Challenge in an Older Adult [PDF]
Geriatrics, Gerontology and AgingGiant cell arteritis is a large-vessel vasculitis usually seen in older adults. The inflammatory process results in systemic, ophthalmic, and neurological lesions. It is difficult to diagnose in older adults and may present as a medical emergency.
Jorge Luiz de Carvalho Mello +4 more
doaj +1 more source
Endothelin-1 promotes vascular smooth muscle cell migration across the artery wall: a mechanism contributing to vascular remodelling and intimal hyperplasia in giant-cell arteritis [PDF]
, 2018 Background: Giant-cell arteritis (GCA) is an inflammatory disease of large/medium-sized arteries, frequently involving the temporal arteries (TA). Inflammation-induced vascular remodelling leads to vaso-occlusive events. Circulating endothelin-1 (ET1) is
Alba, Marco A. +11 more
core +1 more source
Immunology, Volume 177, Issue 4, Page 736-748, April 2026.A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley +1 more source
Safety of Immune Checkpoint Inhibitors in Cancer Patients With Preexisting Autoimmune Vasculitis
ACR Open Rheumatology, Volume 8, Issue 3, March 2026.Objective Immune checkpoint inhibitors (ICIs) are effective cancer therapies but often cause serious immune‐related adverse events (irAEs). Patients with preexisting autoimmune diseases, including vasculitis, are excluded from trials. We aimed to evaluate the frequency, severity, and outcomes of vasculitis flares and irAEs in this population.
Juan Sevillano +4 more
wiley +1 more source