Results 61 to 70 of about 30,694 (259)

Endothelin-1 promotes vascular smooth muscle cell migration across the artery wall: a mechanism contributing to vascular remodelling and intimal hyperplasia in giant-cell arteritis [PDF]

, 2018
Background: Giant-cell arteritis (GCA) is an inflammatory disease of large/medium-sized arteries, frequently involving the temporal arteries (TA). Inflammation-induced vascular remodelling leads to vaso-occlusive events. Circulating endothelin-1 (ET1) is
Alba, Marco A., Cid Xutglà, M. Cinta, Corbera Bellalta, Marc, Espígol Frigolé, Georgina, Hernández Rodríguez, José, Lavilla Grífols, Rodolfo, Lozano Garcia, Ester, Planas Rigol, Ester, Preciado Gallego, Sara, Prieto González, Sergio, Segarra Blasco, Marta, Terrades García, Nekane   +11 more
core   +1 more source

Concurrent central retinal artery occlusion and branch retinal vein occlusion in giant cell arteritis

Clinical Ophthalmology, 2010
Edward R Chu, Celia S ChenDepartment of Ophthalmology, Flinders Medical Centre and Flinders University, Bedford Park, SA, AustraliaAbstract: Ophthalmic involvement in giant cell arteritis can manifest in a number of ways. Central retinal artery occlusion
Edward R Chu, Celia S Chen
doaj  

Genome‐Wide DNA Methylation Study Reveals Specific Signatures in the Affected Arterial Tissue of Patients With Giant Cell Arteritis

Arthritis &Rheumatology, EarlyView.
Objective Giant cell arteritis (GCA) is a large‐vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by identifying specific DNA methylation signatures in the arterial tissue of patients with this vasculitis. Methods DNA methylation profiling was analyzed in 79
Gonzalo Borrego‐Yaniz, Ana Márquez, Elkyn Estupiñán‐Moreno, Laura C. Terrón‐Camero, Miguel A. González‐Gay, Santos Castañeda, Giuliana Guggino, David Saadoun, Pietro Lio, Simona Fontana, Martina Bonacini, Alessandro Rossi, Alberto Cavazza, Francesco Muratore, Carlo Salvarani, Nicolo Pipitone, Javier Martin, Stefania Croci, Lourdes Ortiz‐Fernández   +18 more
wiley   +1 more source

A Case of Sixth Cranial Nerve Palsy and Suspected Giant Cell Arteritis [PDF]

, 2017
Sudden onset of horizontal diplopia in an elderly patient can be due to giant cell arteritis. Although the patient reported was a vasculopath, a concurrent headache, mild reduction in visual acuity, scalp tenderness and raised inflammatory markers lead ...
D'Ath, P., Wilson, C. M.
core  

Shoulder pain due to cervical radiculopathy: an underestimated long-term complication of herpes zoster virus reactivation? [PDF]

, 2018
Purpose To evaluate if herpes zoster virus (HZV) reactivation may be considered in the aetiology of cervical radiculopathy. Methods The study group was composed of 110 patients (52 M-58F;mean age ± SD:46.5 ± 6.12; range:40-73) with a clinical ...
AS Hilibrand, B Kuijper, Ciro Villani, DA Perez-Martienz, Daniele Passaretti, DH Gilden, E Viikari-Juntura, H Sandmark, HC Tong, I Steiner, JP Makela, K Radhakrishnan, KC Shah, KM Abbed, MC Sanchez, MM Ban Le, MM Vargo, MT Modic, MT Modic, NA Peterslund, PG Kennedy, PW Detwiler, R Atkinson, RE Yoss, RS Wainner, RW Johnson, S Gumina, S Shabat, Stefano Gumina, T Fujy, Vittorio Candela, W Frobin, W Frobin, W Frobin, Y Uematsu   +34 more
core   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists, Sodium‐Glucose Cotransporter‐2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases

Arthritis &Rheumatology, Accepted Article.
Objective GLP‐1 receptor agonists (GLP‐1RAs) and SGLT2 inhibitors (SGLT2is) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear. We compared ARD incidence following initiation of GLP‐1RAs, or SGLT2is, vs.
Derin Karacabeyli, Diane Lacaille, Na Lu, Hui Xie, J. Antonio Aviña‐Zubieta   +4 more
wiley   +1 more source

CASE REPORT: Giant Cell Arteritis, a Paraneoplastic Manifestation of Acute Myeloid Leukemia [PDF]

, 2022
Safaa Azzouz, Jonathan How
openalex   +1 more source

Unexpected Giant Right Coronary Artery Aneurysm Diagnosed by Computed Tomography Angiography in the Emergency Department

Journal of Clinical Ultrasound, EarlyView.
3D Volume Rendering coronary CTA reconstruction showing a giant thrombosed aneurysm of the proximal right coronary artery ABSTRACT Giant coronary artery aneurysms (GCAA) are usually defined as diameter > 8 mm or > 400% of the adjacent normal segment; they are very rare (reported prevalence ≈0.02%).
Stefano Giusto Picchi, Giulia Lassandro, Rosita Comune, Filomena Pezzullo, Stefania Tamburrini, Giulio Cocco, Nino Cocco, Domenico Tafuri, Antonio Corvino   +8 more
wiley   +1 more source

Giant Cell Arteritis: A Diagnostic Challenge in an Older Adult [PDF]

Geriatrics, Gerontology and Aging
Giant cell arteritis is a large-vessel vasculitis usually seen in older adults. The inflammatory process results in systemic, ophthalmic, and neurological lesions. It is difficult to diagnose in older adults and may present as a medical emergency.
Jorge Luiz de Carvalho Mello, Raul Sakuma Narita, Frederico Palumbo Araújo, Diba Maria Sebba Tosta de Souza, Vitor Angelo Carluccio Galhardo   +4 more
doaj   +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source