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Variable presentation of giant cell arteritis [PDF]
Giant cell arteritis is a rare disease that can lead to blindness in people older than 50 years. Early recognition and timely treatment can prevent irreversible damage.
Brouwer, E. +5 more
core +5 more sources
Giant cell arteritis may lead to catastrophic, large-vessel complications from chronic vascular wall inflammation without prompt diagnosis and treatment.
Anjeli K. Nayar +3 more
doaj +1 more source
Retractions in Rheumatology: Trends, Causes, and Implications for Research Integrity
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley +1 more source
Mucosal‐Associated Invariant T Cells in Health and Disease
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
ABSTRACT Tocilizumab is an interleukin‐6 (IL‐6) receptor antagonist indicated for various rheumatologic conditions. While hepatotoxicity is a recognized adverse effect, it predominantly manifests as hepatocellular injury. We report a rare case of drug‐induced liver injury (DILI) presenting with a cholestatic pattern and cholangitis features in a 75 ...
Louis‐Edmond Barbaro +7 more
wiley +1 more source
Aortitis in Extracranial Giant Cell Arteritis: Do Not Lose Sight of the Patient
Giant cell arteritis is the most common systemic vasculitis. This case highlights aortic dissection as a potentially life-threatening complication of giant cell arteritis, in most instances occurring as very late event years or even decades after initial
Lilly J.U. Reik +3 more
doaj +1 more source
ABSTRACT Aims People with Type 2 diabetes experience higher cardiometabolic risk, and both synthetic glucocorticoids and use of 5α‐reductase inhibitors have been individually linked to increased risk of myocardial infarction. We tested whether the increase in risk is exacerbated by co‐prescription of both drugs.
Haolan Tu +20 more
wiley +1 more source
Tocilizumab for severe and refractory mucous membrane pemphigoid
Elevated IL‐6 levels identified in mucous membrane pemphigoid support IL‐6 blockade, with tocilizumab demonstrating clinical benefit in nine patients with severe and refractory mucous membrane pemphigoid. Abstract Background Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease involving mucous membranes with a potentially ...
Billal Tedbirt +20 more
wiley +1 more source
Clinical management of clonal hematopoiesis
ABSTRACT Clonal hematopoiesis, particularly clonal hematopoiesis of indeterminate potential and clonal cytopenia of undetermined significance, is an age‐related premalignant condition characterized by the expansion of hematopoietic clones carrying somatic mutations.
Kelly S. Chien +1 more
wiley +1 more source
Doppler ultrasound and giant cell arteritis
Ana Marina Suelves1, Enrique España-Gregori1,2, Jose Tembl3, Stephanie Rohrweck1, Jose Maria Millán4, Manuel Díaz-Llopis1,4,51Service of Ophthalmology, La Fe University Hospital, Valencia, Spain; 2Department of Optics ...
Jose Tembl +3 more
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