Results 81 to 90 of about 23,553 (188)

Rare Gain‐of‐Function Variants in IDH1 and IDH2 Confer Increased Risk of Immune‐Mediated Rheumatic Diseases

ACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Objective Gain‐of‐function variants in IDH1 and IDH2 are enriched among individuals with coexisting myeloid neoplasms and autoimmune diseases. However, the association between IDH1/IDH2 variants and rheumatic diseases independent of hematologic neoplasms remains unclear. We investigated the association between rare gain‐of‐function and loss‐of‐function
Mahmut S. Kaymakci, Mehmet Hocaoğlu, Kenneth J. Warrington, Amr H. Sawalha   +3 more
wiley   +1 more source

The Role of Ultrasound Compared to Biopsy of Temporal Arteries in the Diagnosis and Treatment of Giant Cell Arteritis (TABUL): a diagnostic accuracy and cost-effectiveness study [PDF]

, 2016
Background: Giant cell arteritis (GCA) is a relatively common form of primary systemic vasculitis, which, if left untreated, can lead to permanent sight loss. We compared ultrasound as an alternative diagnostic test with temporal artery biopsy, which may
Albertini, Allison, Amiri, Anon, Arida, Aschwanden, Ashton-Key, Ball, Bernatsky, Bley, Bley, Bley, Boghen, Borchers, Breuer, Brown, Brown, Cavazza, Chakrabarty, Chandran, Chatelain, Chmelewski, Colquitt, Cox, Craven, Curtis, Czihal, Danesh-Meyer, Dasgupta, Dasgupta, Davis, Del Buono, Department of Health, Department of Health, Diamantopoulos, Diamantopoulos, Disdier, Dunstan, Durand, Duru, Dwolatzky, Elliot, Esteban, EuroQol Group, Exley, Farmer, Fitch, Gabriel, Genereau, Gerhard, Germanò, González-Gay, González-Gay, González-Gay, González-Gay, Graham, Guffey Johnson, Guida, Gutiérrez, Gutiérrez, Hamidou, Hauenstein, Hayreh, Hedges, Horton, Hunder, Ikard, Joint Formulary Committee, Kanis, Kaptanis, Karahaliou, Karassa, Kavanaugh, Kisza, Klink, Le, Liozon, Luqmani, Luqmani, Machado, Maguchi, Manson, Mohammad, Mukhtyar, Mukhtyar, Muratore, Murchison, Murchison, National Institute for Health and Care Excellence, NHS Choices, NICE, NICE, Niederkohr, Office for National Statistics (ONS), Patil, Patil, Patil, Pepe, Petursdottir, Piram, Post, Prieto-González, Proven, Puppo, Restuccia, Roberts, Rodondi, Royal National Institute of Blind People, Salvarani, Schmidt, Schmidt, Schmidt, Schmidt, Schmidt, School of Health and Related Research (ScHARR), Siemonsen, Singh, Smeeth, Souza, Suppiah, Tidy, van Staa, Ward, Weyand, Yoon, Ypsilantis, Zenone   +126 more
core   +3 more sources

Dysphagia as the Sole Presentation of Lateral Medullary Syndrome in an Octagerian: A Diagnostic Challenge

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Lateral medullary syndrome (LMS) or Wallenberg's syndrome is usually caused by a cerebrovascular accident of the vertebral artery or the posterior inferior cerebellar artery (PICA), leading to damage to the dorsolateral aspects of the medulla oblongata.
Abera Kuma, Bereket A. Tegene, Sosena Sheleme, Shamil Nuri, Abdulkerim Girma, Sinetibeb Tadesse Amsalu   +5 more
wiley   +1 more source

PTPN22 R620W minor allele is a genetic risk factor for giant cell arteritis [PDF]

, 2016
Published online 7 April 2016.Giant cell arteritis (GCA) is one of the commonest forms of vasculitis in the elderly, and may result in blindness and stroke.
Black, R., Bradbury, L., Brown, M., De Smit, E., Harrison, A., Hewitt, A., Hill, C., Jones, G., Lester, S., Littlejohn, G., Merriman, T., Rischmueller, M., Ruediger, C., Shenstone, B., Smith, M., Wiese, M.   +15 more
core   +2 more sources

Visualization of cranial giant cell arteritis with [18F]FDG PET/CT: A case report

Radiology Case Reports
Giant cell arteritis is a form of large vessel vasculitis which can present with nonspecific symptoms, and if left untreated can cause significant morbidity and/or death. Early diagnosis and management are therefore paramount.
Muhammed Sarjoon Amjadeen, MBBS, Manoj Bhatt, MBBS, FRACP, FAANMS, Evyn Arnfield, MBBS, FRANZCR, FAANMS   +2 more
doaj   +1 more source

Giant cell arteritis

Journal of the Belgian Society of Radiology, 2013
We report the case of a giant cell arteritis (GCA) in an 81-year-old man who presented with headaches and a decreased general condition associated with an important inflammatory syndrome in laboratory analysis responding to corticotherapy.
GC Colin, M Dupont
doaj   +1 more source

The value of [18F]FDG-PET in the diagnosis of large-vessel vasculitis and the assessment of activity and extent of disease [PDF]

, 2018
Purpose: This study was performed to investigate the value of 18F-fluorodeoxyglucose positron emission tomography ([18F]FDG-PET) in the diagnosis of large-vessel vasculitis and the assessment of activity and extent of disease.
Melzer, Ralph, Müller-Brand, Jan, Nitzsche, Egbert, Schindler, Christian, Tyndall, Alan, Walter, Martin   +5 more
core  

Comorbidity in polymyalgia rheumatica [PDF]

, 2018
Polymyalgia rheumatica (PMR) is the commonest inflammatory rheumatic disease affecting older people. The current mainstay of treatment is long-term oral glucocorticoid therapy. Management of these patients in clinical practice is often complicated by the
Chatzigeorgiou, C, Mackie, SL
core   +2 more sources

Giant cell arteritis and scleritis: a rare association

Caspian Journal of Internal Medicine, 2022
Background: Giant cell arteritis (GCA) is a vasculitis of the large and medium-sized arteries in the elderly whose ischemic complications adversely affect the eye.
Abrar-Ahmad Zulfiqar
doaj  

The IL-17 pathway as a target in giant cell arteritis

Frontiers in Immunology
The network of IL-17 cytokines is considered a key component of autoimmune and inflammatory processes. Blocking IL-17 showed great success in psoriasis as well as psoriatic arthritis, and in patients with axial spondyloarthritis.
Markus Zeisbrich, Jens Thiel, Jens Thiel, Nils Venhoff   +3 more
doaj   +1 more source