Results 61 to 70 of about 16,438 (200)
Abstract Purpose To investigate the association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and nonarteritic anterior ischaemic optic neuropathy (NAION) in type 2 diabetes, examining treatment recency and cumulative duration. Methods This nationwide registry‐based nested case–control study utilizedz Danish health registries (1996 ...
Siar Niazi +9 more
wiley +1 more source
Purpose: Giant cell arteritis can have protean manifestations, many of them non-specific. We describe a patient whose initial presentation was most consistent with brainstem stroke, but who was ultimately diagnosed with and treated for giant cell ...
George Sanchez +8 more
doaj +1 more source
Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes +7 more
wiley +1 more source
Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden +3 more
wiley +1 more source
Giant cell arteritis may lead to catastrophic, large-vessel complications from chronic vascular wall inflammation without prompt diagnosis and treatment.
Anjeli K. Nayar +3 more
doaj +1 more source
Utility of ANA in hospitalized patients with headache and suspected systemic autoimmune disease
Abstract Objective This study evaluates antinuclear antibody (ANA) test performance in identifying rheumatologic conditions as the source of the headache. Background ANA testing is widely used to screen for autoimmune diseases in patients with headaches, but its diagnostic utility remains unclear. Methods In this retrospective analytic, cross‐sectional
Erez Magiel +7 more
wiley +1 more source
Abstract Background Polymyalgia rheumatica is the commonest inflammatory condition affecting adults over 50 years of age, however it has been under‐researched and management varies in everyday clinical practice. Aim This national survey of rheumatologists and trainees managing polymyalgia rheumatica (PMR) in Australia sought to determine current ...
Jessica L. Leung +8 more
wiley +1 more source
Giant cell arteritis as a cause of fever of unclear genesis in the elderly
The paper describes a case of giant cell arteritis whose leading clinical sign is long-term fever. It discusses current approaches to diagnosing giant cell arteritis.
S V Guliaev +4 more
doaj
Tocilizumab for severe and refractory mucous membrane pemphigoid
Elevated IL‐6 levels identified in mucous membrane pemphigoid support IL‐6 blockade, with tocilizumab demonstrating clinical benefit in nine patients with severe and refractory mucous membrane pemphigoid. Abstract Background Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease involving mucous membranes with a potentially ...
Billal Tedbirt +20 more
wiley +1 more source
Aortitis in Extracranial Giant Cell Arteritis: Do Not Lose Sight of the Patient
Giant cell arteritis is the most common systemic vasculitis. This case highlights aortic dissection as a potentially life-threatening complication of giant cell arteritis, in most instances occurring as very late event years or even decades after initial
Lilly J.U. Reik +3 more
doaj +1 more source

