Results 61 to 70 of about 23,553 (188)

High frequency of CD95+/CD45RA− regulatory T cells defines an immunosuppressive profile associated with MDS progression

open access: yesBritish Journal of Haematology, EarlyView.
Summary Dynamic interactions between mutated haematopoietic cells and immune cells are key drivers of myelodysplastic neoplasms (MDS) initiation and progression. Regulatory T cells (Tregs) are central mediators of immunosuppression in MDS. We thus aimed to characterize Treg subpopulations in the bone marrow (BM) of MDS patients and to explore their ...
Romain Vazquez   +18 more
wiley   +1 more source

Giant cell arteritis : two cases with acute blindness [PDF]

open access: yes, 2010
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open)Giant cell arteritis is characterized primarily by inflammation in certain large and medium-sized arteries. The major risk factors are age, female
Andri Elfarsson   +2 more
core  

Optimal management of Cogan’s syndrome: a multidisciplinary approach [PDF]

open access: yes, 2017
Cogan's syndrome (CS) is a rare disorder characterized by nonsyphilitic interstitial keratitis (IK) and audio-vestibular symptoms. CS affects mainly young Caucasian adults, mostly during their first three decades of age, and may develop into typical and ...
D'Aguanno, Vittorio   +3 more
core   +1 more source

Utility of ANA in hospitalized patients with headache and suspected systemic autoimmune disease

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study evaluates antinuclear antibody (ANA) test performance in identifying rheumatologic conditions as the source of the headache. Background ANA testing is widely used to screen for autoimmune diseases in patients with headaches, but its diagnostic utility remains unclear. Methods In this retrospective analytic, cross‐sectional
Erez Magiel   +7 more
wiley   +1 more source

Enhancement within the orbits and superficial temporal artery: MRI clues to the diagnosis of giant cell arteritis

open access: yesAmerican Journal of Ophthalmology Case Reports
Purpose: Giant cell arteritis can have protean manifestations, many of them non-specific. We describe a patient whose initial presentation was most consistent with brainstem stroke, but who was ultimately diagnosed with and treated for giant cell ...
George Sanchez   +8 more
doaj   +1 more source

Insights into Imaging of Aortitis [PDF]

open access: yes, 2012
Background: Aortitis is a subtype of the more general term “vasculitis”, an inflammatory condition of infectious or noninfectious origin involving the vessel wall.
Bankier, Alexander   +2 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, Volume 16, Issue 5, Page 821-836, May 2026.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Neurotrophins are expressed in giant cell arteritis lesions and may contribute to vascular remodeling [PDF]

open access: yes, 2014
International audienceIntroduction: Giant cell arteritis (GCA) is characterized by intimal hyperplasia leading to ischaemic manifestations that involve large vessels.
Alexis Régent   +15 more
core   +2 more sources

Quantification of Vascular Burden on Cranial Vessel Wall Magnetic Resonance Imaging and Ophthalmic Complications in Giant Cell Arteritis

open access: yesACR Open Rheumatology, Volume 8, Issue 5, May 2026.
Objective There is a need for measures of disease severity for giant cell arteritis (GCA), which may enable identification of high‐risk subgroups (eg, ophthalmic complications) and individualized approaches to therapy. We derived a continuous score using data from cranial vessel wall magnetic resonance imaging (VW‐MRI) to quantify vascular burden in ...
David L. Yang   +15 more
wiley   +1 more source

Fatal Aortic Dissection in a Patient with Giant Cell Arteritis: A Case Report and Review of the Literature

open access: yesCase Reports in Vascular Medicine, 2013
Giant cell arteritis may lead to catastrophic, large-vessel complications from chronic vascular wall inflammation without prompt diagnosis and treatment.
Anjeli K. Nayar   +3 more
doaj   +1 more source

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