Results 61 to 70 of about 16,438 (200)

Timing and duration of glucagon‐like peptide‐1 receptor agonist use and risk of nonarteritic anterior ischaemic optic neuropathy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To investigate the association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and nonarteritic anterior ischaemic optic neuropathy (NAION) in type 2 diabetes, examining treatment recency and cumulative duration. Methods This nationwide registry‐based nested case–control study utilizedz Danish health registries (1996 ...
Siar Niazi   +9 more
wiley   +1 more source

Enhancement within the orbits and superficial temporal artery: MRI clues to the diagnosis of giant cell arteritis

open access: yesAmerican Journal of Ophthalmology Case Reports
Purpose: Giant cell arteritis can have protean manifestations, many of them non-specific. We describe a patient whose initial presentation was most consistent with brainstem stroke, but who was ultimately diagnosed with and treated for giant cell ...
George Sanchez   +8 more
doaj   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes   +7 more
wiley   +1 more source

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden   +3 more
wiley   +1 more source

Fatal Aortic Dissection in a Patient with Giant Cell Arteritis: A Case Report and Review of the Literature

open access: yesCase Reports in Vascular Medicine, 2013
Giant cell arteritis may lead to catastrophic, large-vessel complications from chronic vascular wall inflammation without prompt diagnosis and treatment.
Anjeli K. Nayar   +3 more
doaj   +1 more source

Utility of ANA in hospitalized patients with headache and suspected systemic autoimmune disease

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study evaluates antinuclear antibody (ANA) test performance in identifying rheumatologic conditions as the source of the headache. Background ANA testing is widely used to screen for autoimmune diseases in patients with headaches, but its diagnostic utility remains unclear. Methods In this retrospective analytic, cross‐sectional
Erez Magiel   +7 more
wiley   +1 more source

Experience of Australian rheumatologists managing polymyalgia rheumatica: results from a national survey

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Polymyalgia rheumatica is the commonest inflammatory condition affecting adults over 50 years of age, however it has been under‐researched and management varies in everyday clinical practice. Aim This national survey of rheumatologists and trainees managing polymyalgia rheumatica (PMR) in Australia sought to determine current ...
Jessica L. Leung   +8 more
wiley   +1 more source

Giant cell arteritis as a cause of fever of unclear genesis in the elderly

open access: yesТерапевтический архив, 2014
The paper describes a case of giant cell arteritis whose leading clinical sign is long-term fever. It discusses current approaches to diagnosing giant cell arteritis.
S V Guliaev   +4 more
doaj  

Tocilizumab for severe and refractory mucous membrane pemphigoid

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Elevated IL‐6 levels identified in mucous membrane pemphigoid support IL‐6 blockade, with tocilizumab demonstrating clinical benefit in nine patients with severe and refractory mucous membrane pemphigoid. Abstract Background Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease involving mucous membranes with a potentially ...
Billal Tedbirt   +20 more
wiley   +1 more source

Aortitis in Extracranial Giant Cell Arteritis: Do Not Lose Sight of the Patient

open access: yesAnnals of Internal Medicine: Clinical Cases
Giant cell arteritis is the most common systemic vasculitis. This case highlights aortic dissection as a potentially life-threatening complication of giant cell arteritis, in most instances occurring as very late event years or even decades after initial
Lilly J.U. Reik   +3 more
doaj   +1 more source

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