Results 71 to 80 of about 30,694 (259)

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

open access: yesImmunology, EarlyView.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Assessing the painful, uninflamed eye in primary care [PDF]

open access: yes, 2015
We acknowledge the important contributions of Professor Amada J Lee, University of Aberdeen, Division of Statistics, for assistance with analysing the data from the patient survey.
Dick, Andrew   +2 more
core   +1 more source

Enhancement within the orbits and superficial temporal artery: MRI clues to the diagnosis of giant cell arteritis

open access: yesAmerican Journal of Ophthalmology Case Reports
Purpose: Giant cell arteritis can have protean manifestations, many of them non-specific. We describe a patient whose initial presentation was most consistent with brainstem stroke, but who was ultimately diagnosed with and treated for giant cell ...
George Sanchez   +8 more
doaj   +1 more source

AB0756 IDENTIFICATION OF HISTOPATHOLOGIC FINDINGS OF PATIENTS WITH GIANT CELL ARTERITIS: A MULTICENTRE STUDY IN THE ERA OF 2022 ACR/EULAR CLASSIFICATION CRITERIA FOR GCA [PDF]

open access: gold, 2023
G. Sandal Uzun   +9 more
openalex   +1 more source

The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui   +11 more
wiley   +1 more source

A genome-wide association study identifies risk alleles in plasminogen and P4HA2 associated with giant cell arteritis [PDF]

open access: yes, 2016
Giant cell arteritis (GCA) is the most common form of vasculitis in individuals older than 50 years in Western countries. To shed light onto the genetic background influencing susceptibility for GCA, we performed a genome-wide association screening in a ...
Abdel Salih   +183 more
core   +9 more sources

Pulmonary Tuberculosis: The Great Mimicker of Lung Cancer

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
Computed tomography (CT) scan of the chest with contrast indicating a soft tissue density in the left upper lobe. ABSTRACT Though tuberculosis (TB) is an ancient pathogen, diagnosis remains challenging. Distinguishing pulmonary tuberculoma, a rare manifestation of TB, from lung cancer is critical.
Laura Corrales‐Diaz Pomatto‐Watson   +2 more
wiley   +1 more source

Fatal Aortic Dissection in a Patient with Giant Cell Arteritis: A Case Report and Review of the Literature

open access: yesCase Reports in Vascular Medicine, 2013
Giant cell arteritis may lead to catastrophic, large-vessel complications from chronic vascular wall inflammation without prompt diagnosis and treatment.
Anjeli K. Nayar   +3 more
doaj   +1 more source

PTPN22 gene polymorphism in Takayasu's arteritis [PDF]

open access: yes, 2008
Objective. Takayasu's arteritis (TA) is a chronic, rare granulomatous panarteritis of unknown aetiology involving mainly the aorta and its major branches.
Akar, S.   +18 more
core   +2 more sources

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