Results 71 to 80 of about 30,694 (259)
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley +1 more source
Assessing the painful, uninflamed eye in primary care [PDF]
We acknowledge the important contributions of Professor Amada J Lee, University of Aberdeen, Division of Statistics, for assistance with analysing the data from the patient survey.
Dick, Andrew +2 more
core +1 more source
Purpose: Giant cell arteritis can have protean manifestations, many of them non-specific. We describe a patient whose initial presentation was most consistent with brainstem stroke, but who was ultimately diagnosed with and treated for giant cell ...
George Sanchez +8 more
doaj +1 more source
AB0756 IDENTIFICATION OF HISTOPATHOLOGIC FINDINGS OF PATIENTS WITH GIANT CELL ARTERITIS: A MULTICENTRE STUDY IN THE ERA OF 2022 ACR/EULAR CLASSIFICATION CRITERIA FOR GCA [PDF]
G. Sandal Uzun +9 more
openalex +1 more source
The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui +11 more
wiley +1 more source
A genome-wide association study identifies risk alleles in plasminogen and P4HA2 associated with giant cell arteritis [PDF]
Giant cell arteritis (GCA) is the most common form of vasculitis in individuals older than 50 years in Western countries. To shed light onto the genetic background influencing susceptibility for GCA, we performed a genome-wide association screening in a ...
Abdel Salih +183 more
core +9 more sources
Pulmonary Tuberculosis: The Great Mimicker of Lung Cancer
Computed tomography (CT) scan of the chest with contrast indicating a soft tissue density in the left upper lobe. ABSTRACT Though tuberculosis (TB) is an ancient pathogen, diagnosis remains challenging. Distinguishing pulmonary tuberculoma, a rare manifestation of TB, from lung cancer is critical.
Laura Corrales‐Diaz Pomatto‐Watson +2 more
wiley +1 more source
Giant cell arteritis may lead to catastrophic, large-vessel complications from chronic vascular wall inflammation without prompt diagnosis and treatment.
Anjeli K. Nayar +3 more
doaj +1 more source
A Case of Subtype Giant Cell Arteritis Without Symptoms of Arteritic Anterior Ischemic Optic Neuropathy [PDF]
Sam Young Jung, Sun Young Shin
openalex +1 more source
PTPN22 gene polymorphism in Takayasu's arteritis [PDF]
Objective. Takayasu's arteritis (TA) is a chronic, rare granulomatous panarteritis of unknown aetiology involving mainly the aorta and its major branches.
Akar, S. +18 more
core +2 more sources

