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Efficacy and safety of JMT103 in patients with unresectable or surgically-challenging giant cell tumor of bone: a multicenter, phase Ib/II study. [PDF]
Nat CommunXu H +29 more
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The tumor-stroma ratio in giant cell tumor of bone: associations with the immune microenvironment and responsiveness to denosumab treatment. [PDF]
J Orthop Surg ResWu HL, Wang XB, Li J, Zheng BW.
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The successful control of multiple pulmonary metastasis from giant cell tumor of bone by monthly denosumab administration: A case report. [PDF]
HeliyonLiu Y, Liu M, Ye Z, Li H.
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GIANT CELL TUMOR OF BONE: A MULTICENTER EPIDEMIOLOGICAL STUDY IN BRAZIL. [PDF]
Acta Ortop BrasBecker RG +5 more
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Excision of a Giant Cell Tumor With Bone Grafting and Bone Cementing of the Proximal Humerus: A Case Report. [PDF]
CureusGharpinde MR +4 more
europepmc +1 more source
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Orthopedic Clinics of North America, 2006
Giant cell tumor is a common benign bone tumor that possesses specific features including location at the end of long bone, a strong tendency toward local recurrence, and the rare capacity to metastasize to the lungs. Preferred treatment usually consists of extensive curettage and filling of the cavity with bone graft or cement.
William M, Mendenhall +4 more
openaire +4 more sources
Giant cell tumor is a common benign bone tumor that possesses specific features including location at the end of long bone, a strong tendency toward local recurrence, and the rare capacity to metastasize to the lungs. Preferred treatment usually consists of extensive curettage and filling of the cavity with bone graft or cement.
William M, Mendenhall +4 more
openaire +4 more sources
Malignancy in giant cell tumor of bone [PDF]
Cancer, 2003 AbstractBACKGROUNDThe term malignant giant cell tumor embraces multiple entities and therefore can be confusing. The goals of the current study were to define the clinicopathologic and histologic features of malignancy in giant cell tumors and to clarify the terminology.METHODSThe authors reviewed all cases from the Rizzoli Institute (Bologna, Italy ...
Patrizia Bacchini
exaly +3 more sources
Radiology, 1958
THE PRESENCE of multinucleated giant cells in a variety of bone lesions has led to inclusion of certain neoplastic, inflammatory, developmental, and metabolic disorders of bone under the diagnosis of giant-cell tumor or giant-cell tumor variant. In 1940, Jaffe, Lichtenstein, and Portis (1) offered a specific definition of giant-cell tumor which has ...
V R, GEE, D G, PUGH
openaire +4 more sources
THE PRESENCE of multinucleated giant cells in a variety of bone lesions has led to inclusion of certain neoplastic, inflammatory, developmental, and metabolic disorders of bone under the diagnosis of giant-cell tumor or giant-cell tumor variant. In 1940, Jaffe, Lichtenstein, and Portis (1) offered a specific definition of giant-cell tumor which has ...
V R, GEE, D G, PUGH
openaire +4 more sources
Radiologic Clinics of North America, 1993
Giant cell tumor is a lesion that usually presents with a radiographically characteristic appearance in a predictable location and patient population. It has a few rare presentations such as pulmonary metastases and multifocal lesions. Prognosis of ultimate tumor behavior is dependent on surgical staging (which requires careful radiographic analysis to
B J, Manaster, A J, Doyle
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Giant cell tumor is a lesion that usually presents with a radiographically characteristic appearance in a predictable location and patient population. It has a few rare presentations such as pulmonary metastases and multifocal lesions. Prognosis of ultimate tumor behavior is dependent on surgical staging (which requires careful radiographic analysis to
B J, Manaster, A J, Doyle
openaire +2 more sources
Journal of the American Academy of Orthopaedic Surgeons, 2013
Giant cell tumor (GCT) of bone is one type of giant cell-rich lesion of bone. This benign mesenchymal tumor has characteristic multinuclear giant cells. Mononuclear stromal cells are the physiologically active and diagnostic cell type. Most GCTs are located in the epiphyseal regions of long bones.
Kevin A, Raskin +4 more
openaire +2 more sources
Giant cell tumor (GCT) of bone is one type of giant cell-rich lesion of bone. This benign mesenchymal tumor has characteristic multinuclear giant cells. Mononuclear stromal cells are the physiologically active and diagnostic cell type. Most GCTs are located in the epiphyseal regions of long bones.
Kevin A, Raskin +4 more
openaire +2 more sources