Results 21 to 30 of about 26,644 (187)

A rare case of neglected long-term pathologic fracture of the distal femur due to a giant cell tumor of bone

Journal of the Bulgarian Orthopaedics and Trauma Association, 2023
Giant cell tumor of bone is a histologically benign bone neoplasia that clinically has an aggressive course. In rare cases, it can give "benign" lung metastases or undergo malignant transformation.
Luben Stokov, Alexandar Kostadinov, Georgi Manolov , Georgi Georgiev, Luben L.Stokov   +4 more
doaj   +3 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

Denosumab for Effective Tumor Size Reduction in Patients With Giant Cell Tumors of the Bone: A Systematic Review and Meta-Analysis

Cancer Control, 2020
Background: Denosumab is a human monoclonal antibody that has been used successfully in the treatment of giant cell tumors of bone. These tumors are rare and, in principle, benign, but they are highly aggressive, locally advanced, osteolytic bone tumors ...
Josef Yayan MD
doaj   +1 more source

Practical Guide to the Design of Granular Hydrogels for Customizing Complex Cellular Microenvironments

Advanced Healthcare Materials, EarlyView.
Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley   +1 more source

Giant cell tumor of bone: A single center study of 115 cases

Journal of Bone Oncology, 2022
Background: Giant cell tumor of bone (GCTB) is a locally aggressive bone tumor that represents about 4–5% of all primary bone tumors. It is characterized by aggressive growth, possible recurrence after surgical treatment and, in rare cases, metastasis ...
Niklas Deventer, Tymoteusz Budny, Georg Gosheger, Anna Rachbauer, Jan Puetzler, Jan Christoph Theil, Dmytrii Kovtun, Marieke de Vaal, Nils Deventer   +8 more
doaj  

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source

CASE OF COMBINED STAGED TREATMENT FOR GIANT CELL TUMOR OF DISTAL EPIPHYSIAL CARTILAGE OF RADIAL BONE

Инновационная медицина Кубани, 2019
We present the case of successful surgical treatment in the patient with a giant cell tumor of distal epithysial cartilage of radial bone. Important feature of this case is a multi-stage combined treatment for the tumor of the radial bone with bone ...
O. V. Sabodashevsky, D. A. Solodky, E. V. Seumyan   +2 more
doaj   +2 more sources

Biopolymer Membranes for Osmotic Power Generation in Bionic Applications

Advanced Materials, EarlyView.
This review provides an overview of biopolymer‐based osmotic power generation for bionic applications. It uniquely bridges biopolymer membranes, reverse electrodialysis(RED), and bionic applications, addressing a critical research gap by integrating biopolymer membranes with RED technologies for biomedical use.
Changchun Yu, Fenghuan Jia, Dong Chen, Ziyi Wang, Pawel Wagner, Yong Liu, Caiyun Wang   +6 more
wiley   +1 more source

Giant cell tumor of bone revisited

SICOT-J, 2017
Giant cell tumor (GCT) of bone is a locally aggressive benign neoplasm that is associated with a large biological spectrum ranging from latent benign to highly recurrent and occasionally metastatic malignant bone tumor.
Mavrogenis Andreas F., Igoumenou Vasileios G., Megaloikonomos Panayiotis D., Panagopoulos Georgios N., Papagelopoulos Panayiotis J., Soucacos Panayotis N.   +5 more
doaj   +1 more source