Results 61 to 70 of about 26,644 (187)

Fabrication of Lithium/Strontium‐Releasing Smart Bioactive Glasses with Anti‐Inflammatory and Osteogenic Effects Tailored to Pathological Stages

Macromolecular Bioscience, EarlyView.
Bioactive glasses with controllable dual ion release capability are developed to aid bone regeneration. The bioactive glasses rapidly release lithium ions that exert an anti‐inflammatory effect, suppressing inflammation after bone injury. Simultaneously, the bioactive glasses slowly release strontium ions, which support bone formation by suppressing ...
Hirohiko Sakai, Jun‐Ichi Sasaki, Haruaki Kitagawa, Gabriela L. Abe, Tomoki Kohno, Naoya Funayama, Satoshi Imazato   +6 more
wiley   +1 more source

Denosumab versus zoledronic acid in cases of surgically unsalvageable giant cell tumor of bone: A randomized clinical trial

Journal of Bone Oncology, 2019
Background: Although denosumab has been approved as an antiresorptive agent for giant cell tumor of bone, its efficacy has not been proven. Objectives: To compare the efficacy and safety of denosumab and zoledronic acid treatment in patients with ...
Shenglong Li, Peng Chen, Qiankun Yang
doaj  

Two Cases of Sarcoma Arising in Giant Cell Tumor of Bone Treated with Denosumab

Case Reports in Medicine, 2015
Giant cell tumor (GCT) of bone is a generally benign, but often locally aggressive, neoplasm of bone, with a propensity for recurrence. Sarcomatous transformation is rare and typically occurs with a history of recurrences and radiation treatment ...
Cory Julian Broehm, Erika L. Garbrecht, Jeff Wood, Therese Bocklage   +3 more
doaj   +1 more source

A recurrent giant cell tumor of bone treated with denosumab

Clinics and Practice, 2015
Although the giant cell tumor of bone is generally classified as a benign tumor it can rarely metastasize and has a potential risk of local recurrence. We want to report about a female patient who suffered from a recurrence of a giant cell tumor of bone ...
Nicola Stadler, Thomas Fingernagel, Stefan G. Hofstaetter, Klemens Trieb   +3 more
doaj   +1 more source

Expert Perspective: Hematologic Malignancies and Vasculitis

Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Features of histological structure and differential diagnostics of the diffuse-type giant cell tumor and its malignant form.

Морфологія, 2016
Background. Tenosynovial giant cell tumor of diffuse type is one of the most widespread tumor of joints, causing destruction of the soft tissues and bone articular surfaces. Objective.
E. A. Dyadyk, A. V. Hryhorovska
doaj   +1 more source

Clinical Features and Therapeutic Evaluation of Central Nervous System Involvement in Pediatric Anaplastic Large Cell Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study analyzed the clinical features of central nervous system involvement (CNS3) in pediatric anaplastic large cell lymphoma (ALCL) and evaluated the CNCL‐ALCL‐2017 treatment protocol efficacy. Methods The clinical data of 215 pediatric ALCL patients aged ≤18 years, including 16 with CNS3, treated following the CNCL‐ALCL‐2017 ...
Xiaomei Yang, Jing Yang, Shuang Huang, Yanlong Duan, Ling Jin, Lian Du, Luping Ding, Mincui Zheng, Pan Wu, Ying Liu, Bo Hu, Yunpeng Dai, Guotao Guan, Ansheng Liu, Shuang Qin, Leping Zhang, Yueping Jia, Lirong Sun, Jian Jiang, Jian Wang, Lijun Qu, Xiaojun Yuan, Yushuang Dong, Wei Liu, Jianwen Zhou, Baoxi Zhang, Chunju Zhou, Zifen Gao, Fu Li, Yonghong Zhang   +29 more
wiley   +1 more source

Cystic Lesions of Bone Resembling Giant Cell Tumors [PDF]

, 1962
T Hiertonn, E. Salén
openalex   +1 more source

Vertebral canine myxosarcoma with neurological signs treated by vertebroplasty and radiotherapy (in a dog)

Veterinary Record Case Reports, EarlyView.
Abstract Canine myxosarcomas are an uncommon group of tumours, with therapeutic modalities still under research. This case report describes a vertebral myxosarcoma in a 5‐year‐old, mixed‐breed dog causing pelvic limb ataxia. Diagnostic modalities included computed tomography and histopathology.
Flavie Deschildre, Charles Porsmoguer, Nicolas Diop, Noah Lauwereys, Margaux Blondel   +4 more
wiley   +1 more source