Results 71 to 80 of about 72,717 (274)

Challenges of denosumab in giant cell tumor of bone, and other giant cell-rich tumors of bone

Current Opinion in Oncology, 2019
Purpose of review Giant cell tumor of bone (GCTB) is an uncommon benign primary bone tumor, consisting of receptor activator of nuclear factor kappa-B (RANK) expressing reactive osteoclast-like giant cells and neoplastic spindle-shaped cells.
A. Lipplaa, S. Dijkstra, H. Gelderblom
semanticscholar   +1 more source

Histological Regression of Giant Cell Tumor of Bone Following RANK Ligand Inhibition

Journal of Investigative Medicine High Impact Case Reports, 2014
Lung metastases are a rare complication of giant cell tumors of bone. We herein describe an interesting case of histological regression and size reduction of lung metastases originating from a primary giant cell tumor of bone in response to the RANK ...
Martin F. Dietrich MD, PhD, Dominick Cavuoti MD, Michael Landay MD, Yull E. Arriaga MD   +3 more
doaj   +1 more source

Imaging of giant cell tumor of bone

Indian Journal of Orthopaedics, 2007
Giant cell tumor (GCT) of bone is a benign but locally aggressive and destructive lesion generally occurring in skeletally mature individuals. Typically involving the epiphysiometaphyseal region of long bones, the most common sites include the distal femur, proximal tibia and distal radius.
Purohit, Shaligram, Pardiwala, Dinshaw N
openaire   +3 more sources

Giant-Cell Tumor of the Distal Ulna Treated by Wide Resection and Ulnar Support Reconstruction: A Case Report

Case Reports in Medicine, 2010
Giant-cell tumor of bone occurred in the distal end of the ulna is extremely uncommon. A 23-year-old male had a giant-cell tumor occurred in the distal end of the ulna.
Akio Minami, Norimasa Iwasaki, Kinya Nishida, Makoto Motomiya, Katsuhisa Yamada, Daisuke Momma   +5 more
doaj   +1 more source

Extramedullary Plasmacytoma of Soft Tissues and Gingiva [PDF]

, 2012
Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm of soft tissue without bone marrow involvement or other systemic characteristics of multiple myeloma. It accounts for 3% of all plasma cell tumors.
Jena, M, Kaler, AK, Shankar, A
core  

Do we need internal fixation devices for giant cell tumors around knee joint? An outcome study

Journal of Orthopaedic Diseases and Traumatology, 2018
Introduction: Giant cell tumors around the knee joint are the most common aggressive benign tumors. Several limb sparing and limb ablation surgeries are practiced with varying level of success.
Ritesh Runu, Vidya Sagar, Ashutosh Kumar, Arnab Sinha, Santosh Kumar   +4 more
doaj   +1 more source

Giant cell tumor of the distal ulna: a case report

Journal of Medical Case Reports, 2012
Introduction Several cases of long bone giant cell tumor have been reported in the literature. We report the case of a patient with a giant cell tumor in the distal ulna. This is very unusual, with a reported incidence of 0.45 to 6%.
Vanni Daniele, Pantalone Andrea, Andreoli Elda, Caldora Patrizio, Salini Vincenzo   +4 more
doaj   +1 more source

Spinal giant cell tumor in tuberous sclerosis: case report and review of the literature. [PDF]

, 2013
BACKGROUND: Patients affected by tuberous sclerosis (TS) have a greater incidence of tumors than the healthy population. Spinal tumours in TS are reported very rarely and consist mainly of sacrococcygeal and cervical chordomas. METHOD: Case report.
Fraioli, C, Fraioli, MF, Lecce, M, Paolo, C   +3 more
core   +1 more source

Giant cell tumor of the bone with fatal pulmonary metastasis: A case report

SAGE Open Medical Case Reports
Giant cell tumors of the bone are typically benign, locally aggressive lesions that rarely metastasize. In this report, we describe the case of a 48-year-old woman presenting with a giant cell tumor of the bone of the hip joint, which demonstrated ...
Mohamad Taha, Saadia A. Faiz, Pushan Jani, Jing Liu, Yasir D. Ali, Mohammad Asim Amjad   +5 more
doaj   +1 more source

Patellar Giant-Cell Tumor: a Case Report

Journal of Experimental Life Science, 2018
Giant cell tumor (GCT) found mostly in the long bones metaphysis or epiphysis. GCT usually occur between the ages of a third and fourth decade and locally aggressive. Giant-Cell Tumor seldom affects the patella. Multicentric forms rarely reported.
Istan Irmansyah Irsan, Satria Pandu Persada, Rakhmad Aditya   +2 more
doaj   +1 more source