Results 51 to 60 of about 30,224 (246)

The small molecule ephrin receptor inhibitor, GLPG1790, Reduces renewal capabilities of cancer stem cells, showing anti-tumour efficacy on preclinical glioblastoma models [PDF]

, 2019
Therapies against glioblastoma (GBM) show a high percentage of failure associated with the survival of glioma stem cells (GSCs) that repopulate treated tumours.
Beirinckx, Filip, Colapietro, Alessandro, Cristiano, Loredana, Delle Monache, Simona, Festuccia, Claudio, Gravina, Giovanni, Lorenzon, Giocondo, Mancini, Andrea, Marampon, Francesco, Martellucci, Stefano, Mattei, Vincenzo, Pujuguet, Philippe, Saniere, Laurent, Sferra, Roberta, van der Aar, Ellen, Vitale, Flora   +15 more
core   +2 more sources

A Newer Technique of Distal Ulna Reconstruction Using Proximal Fibula and TFCC Reconstruction Using Palmaris Longus Tendon following Wide Resection of Giant Cell Tumour of Distal Ulna

Case Reports in Orthopedics, 2013
Giant cell tumour of the bone (GCT) is a rare locally aggressive primary bone tumour with an incidence of 3% to 5% of all primary bone tumours. The most common location for this tumour is the long bone metaepiphysis especially of the distal femur ...
Elango Mariappan, Pragash Mohanen, Justin Moses   +2 more
doaj   +1 more source

Giant Cell Tumor with Aneurysmal Bone Cyst Changes of Proximal Fibula in a Young Male - A Case Report

Journal of Clinical and Biomedical Sciences, 2020
Giant cell tumor (GCT) account around 5% of bone tumors with a slight female preponderance. We are presenting a case 32yr old gentleman, who presented with c/o swelling present on lateral aspect of proximal third of left leg for past one year ...
Sakthikesavan sivanandan, Hariprasad seenappa, Satyarup Dassanna, Varsha Shree R   +3 more
doaj   +1 more source

A very rare case of metachronous multicentric giant cell tumor of bone with benign lung metastasis in form of a very large mass lesion [PDF]

Journal of Cardio-Thoracic Medicine, 2018
Giant cell tumour (GCT) is a benign, locally aggressive tumour of the bone that accounts for 5% of primary bone tumours and 21% of benign bone tumours. This tumour more commonly presents as a single (solitary) lesion; however, it may appear with multiple
Shekhar Gangadhar Kadam, Susheel Bindroo, Jithin Krishnan, Hina Jayantilal Shah, Vikram Ramchandra Lele, Ganapathi Bhat   +5 more
doaj   +1 more source

Malignant Giant-Cell Tumour of Bone

Journal of British Surgery, 1932
Summary The malignant giant cell tumour of bone is described here as the malignant growth which contains many foreign body giant cells (osteoclasts). This tumour is at first localized to one part of a bone, radiologically shows characteristic trabeculation and histologically shows a structure closely resembling that of the benign giant cell tumour ...
openaire   +2 more sources

Hydrogen Peroxide Wound Irrigation in Orthopaedic Surgery. [PDF]

, 2017
As the burden of deep hardware infections continues to rise in orthopaedics, there is increasing interest in strategies for more effective debridement of colonized tissues and biofilm.
Hansen, Erik Nathan, Lu, Min
core   +1 more source

Surgical treatment of retrosternal extraosseous Ewing Sarcoma in a 6-years old female: a clamshell approach with hemysternectomy and application of a non-crosslinked extracellular matrix [PDF]

, 2017
Background Ewing Sarcoma (ES) and Neuroblastoma (NB) belong to a family of tumours of primitive neuroectodermal origin (PNET) that occurs in both bone and soft tissue. Notwithstanding ES and NB are two distinct malignant tumours, sometimes there could be
Angotti, Rossella, Casini, Leonardo, CLERICO, Anna, Luzzi, Luca, Messina, Mario, Molinaro, Francesco, Paladini, Piero, Pellegrino, Chiara, SCHIAVETTI, Amalia, Varrasso, Giulia   +9 more
core   +3 more sources

Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles, Greg Russell, Leila H. DeWitt, Kimberly Montez, Callie L. Brown   +4 more
wiley   +1 more source

Spinal cord compression secondary to brown tumour in a patient on long-term haemodialysis: a case report. [PDF]

, 2009
Brown tumours may occur secondary to hyperparathyroidism in patients with chronic renal failure (CRF). Diagnosing a spinal brown tumour causing cord compression requires a high index of suspicion.
Luk, KD, Mak, KC, Wong, YW
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source