Results 41 to 50 of about 167,867,171 (233)

Recurrent Giant cell tumour in distal Humerus: A Case report

Journal of Orthopaedic Case Reports, 2013
Introduction: Giant cell tumour of bone (GCT) is a common benign primary bone tumour, seen commonly in the distal Femur, proximal Tibia and distal Radius. Very few cases of GCT are reported in distal humerus.
Y Bhanu Rekha, Y Poornachandra Rao
doaj   +1 more source

Malignant Giant-Cell Tumour of Bone

Journal of British Surgery, 1932
Summary The malignant giant cell tumour of bone is described here as the malignant growth which contains many foreign body giant cells (osteoclasts). This tumour is at first localized to one part of a bone, radiologically shows characteristic trabeculation and histologically shows a structure closely resembling that of the benign giant cell tumour ...
openaire   +2 more sources

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Effects of Thermoablation with or without Caffeine on Giant Cell Tumour of Bone

Journal of Orthopaedic Surgery, 2015
Purpose. To evaluate the effect of caffeine on the apoptosis rate of giant cell tumour of bone cells during thermoablation. Methods. Giant cell tumour of bone tissue (2 cm 3 ) was collected from 10 patients. Cells were incubated at 37°C, 40°C, 45°C, 50°C,
Rapin Pimolsanti, Adisak Wongkajornsilpa, Pojchong Chotiyarnwong, Apichart Asavamongkolku, Saranatra Waikakul   +4 more
doaj   +1 more source

DNA methylation profile discriminates sporadic giant cell granulomas of the jaws and cherubism from their giant cell‐rich histological mimics

The Journal of Pathology: Clinical Research, 2023
Sporadic giant cell granulomas (GCGs) of the jaws and cherubism‐associated giant cell lesions share histopathological features and microscopic diagnosis alone can be challenging.
Letícia Martins Guimarães, Daniel Baumhoer, Vanghelita Andrei, Dennis Friedel, Christian Koelsche, Ricardo Santiago Gomez, Andreas von Deimling, Carolina Cavalieri Gomes   +7 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

A Newer Technique of Distal Ulna Reconstruction Using Proximal Fibula and TFCC Reconstruction Using Palmaris Longus Tendon following Wide Resection of Giant Cell Tumour of Distal Ulna

Case Reports in Orthopedics, 2013
Giant cell tumour of the bone (GCT) is a rare locally aggressive primary bone tumour with an incidence of 3% to 5% of all primary bone tumours. The most common location for this tumour is the long bone metaepiphysis especially of the distal femur ...
Elango Mariappan, Pragash Mohanen, Justin Moses   +2 more
doaj   +1 more source

Giant Cell Tumor with Aneurysmal Bone Cyst Changes of Proximal Fibula in a Young Male - A Case Report

Journal of Clinical and Biomedical Sciences, 2020
Giant cell tumor (GCT) account around 5% of bone tumors with a slight female preponderance. We are presenting a case 32yr old gentleman, who presented with c/o swelling present on lateral aspect of proximal third of left leg for past one year ...
Sakthikesavan sivanandan, Hariprasad seenappa, Satyarup Dassanna, Varsha Shree R   +3 more
doaj   +1 more source

A very rare case of metachronous multicentric giant cell tumor of bone with benign lung metastasis in form of a very large mass lesion [PDF]

Journal of Cardio-Thoracic Medicine, 2018
Giant cell tumour (GCT) is a benign, locally aggressive tumour of the bone that accounts for 5% of primary bone tumours and 21% of benign bone tumours. This tumour more commonly presents as a single (solitary) lesion; however, it may appear with multiple
Shekhar Gangadhar Kadam, Susheel Bindroo, Jithin Krishnan, Hina Jayantilal Shah, Vikram Ramchandra Lele, Ganapathi Bhat   +5 more
doaj   +1 more source

WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A‐Mediated Regulation of CSF1R Signaling in Estrogen‐Deficient Osteoporosis

Advanced Science, EarlyView.
Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen, Xin Liu, Gaoran Ge, Li Xu, Ziyu Zhang, Chang Lv, Hao Xu, Wenhao Li, Yi Qin, Qifeng Sheng, Qihan Wang, Hongxia Li, Jun Zhou, Huilin Yang, Dechun Geng   +14 more
wiley   +1 more source