Results 21 to 30 of about 167,867,171 (233)

Giant cell tumour of bone

, 2014
From 1982 to 1987, 4 cases with giant cell tumour of bone surgically treated in our clinic are presented. Tumor localizations were at talus, distal radial edge, proximal humeral edge and distal femoral metaphysis respectively. Two cases treated with curettage, and grafting and the other two received local resection and grafting.
HUNER, Hakan, CETİNUS, Ercan, CEVER, İlhan, DEMİRYONTAR, Nejat   +3 more
  +5 more sources

Radiological and Histopathological Outcome of Giant Cell Tumor of Femur with Denosumab Treatment: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2016
Giant Cell Tumour of Bone (GCTB) is a benign but locally aggressive osteolytic skeletal neoplasm of young adults consisting of giant cells expressing RANK (Receptor Activator of Nuclear Factor-κB) and mesenchymal spindle-like stromal cells expressing ...
Preethi Dileep Menon, R. Krishnakumar, Annie Jojo   +2 more
doaj   +1 more source

Current indications for denosumab in benign bone tumours

EFORT Open Reviews, 2023
Denosumab is a fully humanised monoclonal antibody to RANK ligand, inhibiting the RANK–RANKL pathway. It promotes the apoptosis of osteoclast-like giant cells, a secondary ossification and connective tissue formation. Given its high efficacy, denosumab
Antal Imre, Sápi Zoltán, Szendrői Miklós   +2 more
doaj   +1 more source

Clinico radiological Presentation and Management of Giant Cell Tumour of Calcaneum: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2023
Giant cell tumours of bone are typically benign tumours composed of mononuclear and multinucleated giant cells that are osteoclastically active. They typically develop in long bones but can also appear in unexpected locations. In this case report, a 36-
Ram Rodge, Shubham Rodge, Arun Kumar Rao, Tejas Gadekar   +3 more
doaj   +1 more source

Giant cell tumour of the femoral neck: Failure of curettage–cavity filling cementation with screw fixation, a case report

Trauma Case Reports, 2019
Background: Giant cell tumours are common primary long bone tumours with femoral neck locations infrequent and notorious for pathological fractures. Treatment with simple curettage often results in local recurrence.
S. Abdulrazak, A. Marzouki, S.T. Bah, K. Lahrach, F. Boutayeb   +4 more
doaj   +1 more source

Diagnostic value of H3F3A mutations in giant cell tumour of bone compared to osteoclast-rich mimics [PDF]

, 2015
Driver mutations in the two histone 3.3 (H3.3) genes, H3F3A and H3F3B, were recently identified by whole genome sequencing in 95% of chondroblastoma (CB) and by targeted gene sequencing in 92% of giant cell tumour of bone (GCT). Given the high prevalence
Tarpey Patrick Campbell Peter, J., Gernot Jundt, A Bassim Hassan, Presneau, Nadège, Jundt Gernot, Van Loo Peter Hassan A Bassim, Rifat Hamoudi, Daniel Baumhoer, Bhavisha Khatri, Behjati Sam, Campbell Peter J., Tarpey, P, Pillay, N, Sam Behjati, Loo, PV, Patrick Tarpey, Tirabosco, R, Baumhoer Daniel, Tirabosco, R., Roberto Tirabosco, Ye Hongtao, Presneau, N, Pillay Nischalan, Nischalan Pillay, Khatri, B., Flanagan, AM, Amary, M.F., Hamoudi Rifat Wedge David, C., Baumhoer, D, Campbell, PJ, Peter Van Loo, Nadège Presneau, M Fernanda Amary, Hassan A. Bassim, Hassan, AB, Khatri, B, Amary, MF, Wedge, DC; id_orcid, David C Wedge, Adrienne M Flanagan, Behjati, S, Hongtao Ye, Flanagan, A.M., Peter J Campbell, Jundt, G, Ye, H, Wedge David C., Hamoudi, R   +47 more
core   +1 more source

Plexiform Fibrohistiocytic Tumour at a Rare Site: Frontal Region of Head with underlying Frontal Bone Invasion [PDF]

Journal of Clinical and Diagnostic Research, 2022
Plexiform Fibrohistiocytic Tumour (PFHT) is an intermediate malignant tumour of soft tissue. It is a rarely metastasising dermal subcutaneous neoplasm. It affects children and young adults. The age range of presentation is from birth to age 77 years. The
Sarita Nibhoria, Ekta Rani, Aradhana Singh Hada, Bikramjit Singh, Ruth Prakash   +4 more
doaj   +1 more source

An Unusual Cause of Elbow Pain – A Case Report [PDF]

Journal of Krishna Institute of Medical Sciences University, 2016
Giant cell tumours are common bone tumours usually benign which arise at the metaphysis and extend towards the epiphysis of bone. A case of giant cell tumour in the distal humerus which is a rare site is presented here.
Fazeel Ibrahim, Venkatraman Indiran, V. Vijay Narasimman, Prabakaran Maduraimuthu   +3 more
doaj  

Soft Tissue Giant Cell Tumour of Low Malignant Potential: A Rare Tumour at a Rare Site [PDF]

Journal of Clinical and Diagnostic Research, 2013
“Soft tissue giant cell tumour of low malignant potential” is considered as the soft tissue counterpart of osteoclastoma of the bone. It is a primary soft tissue tumour which is classified under the category of fibrohistiocytic tumours of intermediate ...
Amoolya Bhat, Geethamani V., Vijaya C.
doaj   +1 more source

Grade 3 Giant Cell Tumour of the Distal Humeral Epiphysis Treated with Intralesional Curettage, High Speed Burring and Bone Grafting: A Case Report [PDF]

Malaysian Orthopaedic Journal, 2022
Giant cell tumours of bone are benign but locally aggressive neoplasms involving the epi- and metaphysis of long bones. Tumours of the distal humeral epiphysis with cortical disruption and invasion into the joint and the soft tissues are rare and ...
Nyffeler RW, Ziebarth K
doaj   +1 more source