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While giant cell tumour of bone is a relatively common tumour in adults, it is exceedingly rare in children. Multicentric metachronous giant cell tumour is an even rarer presentation of this tumour in skeletally immature patients.
Farokh Wadia +4 more
doaj +1 more source
Accuration of Fine Needle Aspiration Biopsy in Musculoskeletal Tumour [PDF]
Fine needle aspiration biopsy (FNAB) has been reported to be the preferable choice of biopsy for musculoskeletal tumour. While FNAB appears to have advantages to core biopsy in the aspect of simplicity and cost, the diagnostic accuracy should be the most
Dewo, P. (Punto) +3 more
core +4 more sources
Bone: Giant cell tumour of bone [PDF]
Review on giant cell tumor of bone, with data on clinics, histopathology and ...
Cleven, Arjen, Bovée, Judith
openaire +2 more sources
Giant cell angioblastoma is a relatively rare vasogenic tumour. To date, studies on its clinical manifestations, imaging characteristics, pathological features, and prognosis are extremely limited and unknown, with only a few cases recorded.
Qingbin Li +13 more
doaj +1 more source
Clinico radiological Presentation and Management of Giant Cell Tumour of Calcaneum: A Case Report [PDF]
Giant cell tumours of bone are typically benign tumours composed of mononuclear and multinucleated giant cells that are osteoclastically active. They typically develop in long bones but can also appear in unexpected locations. In this case report, a 36-
Ram Rodge +3 more
doaj +1 more source
Denosumab and giant cell tumour of bone-a review and future management considerations. [PDF]
Xu SF, Adams B, Yu XC, Xu M.
europepmc +2 more sources
Giant-cell tumour of proximal radius in a 50-year-old female with wrist drop: a rare case report [PDF]
Giant-cell tumour is a locally aggressive tumour of long bones of epiphyseal region commonly occurring in adults aged 20–40 years. Most common location is distal femur, proximal tibia, and distal radius.
Anshul Dahuja +5 more
core +2 more sources
Radiological and Histopathological Outcome of Giant Cell Tumor of Femur with Denosumab Treatment: A Case Report [PDF]
Giant Cell Tumour of Bone (GCTB) is a benign but locally aggressive osteolytic skeletal neoplasm of young adults consisting of giant cells expressing RANK (Receptor Activator of Nuclear Factor-κB) and mesenchymal spindle-like stromal cells expressing ...
Preethi Dileep Menon +2 more
doaj +1 more source
Current indications for denosumab in benign bone tumours
Denosumab is a fully humanised monoclonal antibody to RANK ligand, inhibiting the RANK–RANKL pathway. It promotes the apoptosis of osteoclast-like giant cells, a secondary ossification and connective tissue formation. Given its high efficacy, denosumab
Antal Imre +2 more
doaj +1 more source
Clinical, histological and prognostic features of a novel nail-bed lesion of cats: 41 cases [PDF]
There is a distinct subset of lesions arising on the digits of cats, located at or close to the nail-bed epithelium, which are typically composed of proliferative fibroblast-like cells, multinucleate giant cells and areas of osseous metaplasia, but ...
Dobromylskyj, M J +4 more
core +1 more source

