Results 1 to 10 of about 16,437 (151)

The Role of Denosumab for Surgical Outcomes in Patients with Giant Cell Tumour of Bone: A Systematic Review [PDF]

open access: yesCurrent Oncology, 2021
Background: The role of denosumab in patients with resectable giant cell tumour of bone remains unclear. We asked the following research question: for patients (aged ≥ 12 years) with resectable giant cell tumour of bone, what are the benefits and harms ...
Abha Gupta   +5 more
doaj   +2 more sources

Giant cell tumour of bone in os sacrum of a prepubertal girl – Surgical and medical treatment with zoledronate and denosumab [PDF]

open access: yesBone Reports, 2023
A giant cell tumour of bone presented in the os sacrum of a prepubertal girl. Surgery with reconstruction was performed, but total resection was impossible.
Signe Sparre Beck-Nielsen   +5 more
doaj   +2 more sources

The use of denosumab in the setting of acute pathological fracture through giant cell tumour of bone [PDF]

open access: yesWorld Journal of Surgical Oncology, 2021
Background Denosumab (XgevaTM) is a fully human antibody to RANK-Ligand, an important signal mediator in the pathogenesis of giant cell tumour of bone (GCTB).
Wolfram Weschenfelder   +2 more
doaj   +2 more sources

Management and surveillance of metastatic giant cell tumour of bone [PDF]

open access: yesPathology and Oncology Research
Giant cell tumour of bone (GCTB) is viewed as a benign, locally aggressive primary bone tumour with metastatic potential. Current management is surgery with bone curettage or resection and systemic therapy with denosumab.
David Fellows   +8 more
doaj   +2 more sources

Giant Cell Tumour of Soft Tissue in Neck: An Uncommon Tumour in an Uncommon Location [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Giant cell tumour of soft tissue is an extremely rare tumour. It is thought to be the soft tissue counterpart of giant cell tumours of the bone due to its histological and immunohistochemical resemblances.
Abhishek Bandyopadhyay   +4 more
doaj   +1 more source

Aggressive Giant Cell Tumour of Talus with Pulmonary Metastasis-A Rare Presentation [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Giant cell tumour (GCT) is a primary benign neoplasm of bone. It is classically described as a locally invasive tumour that occurs close to the joint of a mature bone. It accounts for 5% of all skeletal tumours.
B Udaya Kumar   +3 more
doaj   +1 more source

Utility of p63 in Giant Cell Lesions of Bone- A Case Series [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2022
Giant cell lesions of bone include a relatively large group of biologically and morphologically diverse bone lesions which shows presence of numerous multinucleate osteoclast like giant cells.
Shima Kannadas   +4 more
doaj   +1 more source

Metachronous multicentric giant cell tumour of bone in a 12-year-old girl: A case report and review of literature

open access: yesJournal of Orthopaedics, Trauma and Rehabilitation, 2021
While giant cell tumour of bone is a relatively common tumour in adults, it is exceedingly rare in children. Multicentric metachronous giant cell tumour is an even rarer presentation of this tumour in skeletally immature patients.
Farokh Wadia   +4 more
doaj   +1 more source

Bone: Giant cell tumour of bone [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2018
Review on giant cell tumor of bone, with data on clinics, histopathology and ...
Cleven, Arjen, Bovée, Judith
openaire   +2 more sources

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