Results 61 to 70 of about 351,956 (301)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Frontiers in Plant ScienceRoot-knot nematodes are polyphagous parasitic nematodes that cause severe losses in the agriculture worldwide. They enter the root in the elongation zone and subtly migrate to the root meristem where they reach the vascular cylinder and establish a ...
Jose Domínguez-Figueroa +3 more
doaj +1 more source
Phase cinematographic observation on the multinucleated giant cells infected with measles virus [PDF]
, 1965 The normal mitotic dog kidney cell division and the multinucleated giant cell formation and degeneration of the dog kidney cells infected with measles virus were observed by the phase-cinematography.
Tawara, Jutaro
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
GIANT CELLS AND GIANT CELL LESIONS OF ORAL CAVITY- A REVIEW
Cumhuriyet Dental Journal, 2014 Giant cells are large mononucleated or multinucleated cells that are seen in a variety of physiological as well as pathological conditions. Multinucleated giant cells (MGCs) are important mediators of tissue remodeling and repair and also for removal of ...
Ashish Shrestha +3 more
doaj +1 more source
The organisation of spinoparabrachial neurons in the mouse [PDF]
, 2015 The anterolateral tract (ALT), which originates from neurons in lamina I and the deep dorsal horn, represents a major ascending output through which nociceptive information is transmitted to brain areas involved in pain perception.
Cameron, Darren +5 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Floret-like multinucleated giant cells in neurofibroma
Diagnostic Pathology, 2007 This short report discusses a case of neurofibroma containing floret-like multinucleated giant cells. This being the second such case in the literature.
Golka Dariusz, Shaktawat Sameer
doaj +1 more source
Fungal cell gigantism during mammalian infection. [PDF]
PLoS Pathogens, 2010 The interaction between fungal pathogens with the host frequently results in morphological changes, such as hyphae formation. The encapsulated pathogenic fungus Cryptococcus neoformans is not considered a dimorphic fungus, and is predominantly found in ...
Oscar Zaragoza +5 more
doaj +1 more source
Root-knot nematode feeding site development is impaired by cyclin-dependent kinase inhibitors [PDF]
, 2012 Plant-parasitic nematodes of the genera Meloidogyne trigger the formation of giant cells that undergo recurring acytokinetic mitosis and endocycles. Expression analyses of key cell cycle genes showed their early induction in the nematode feeding site ...
Abad, Pierre +5 more
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