Results 101 to 110 of about 19,800 (242)

Studying antibiotic–membrane interactions via X‐ray diffraction and fluorescence microscopy

FEBS Open Bio, 2015
Antibiotic drug resistance is a serious issue for the treatment of bacterial infection. Understanding the resistance to antibiotics is a key issue for developing new drugs.
Yi-Ting Sun, Ping-Yuan Huang, Cheng-Hao Lin, Kuan-Rong Lee, Ming-Tao Lee   +4 more
doaj   +1 more source

A supramolecular system mimicking the infection process of an enveloped virus through membrane fusion

Scientific Reports, 2023
Membrane fusion is an essential step for the entry of enveloped viruses, such as human immunodeficiency virus and influenza virus, into the host cell, often triggered by the binding of membrane proteins on the viral envelope to host cell membrane ...
Hiroto Furukawa, Yuuna Kimura, Hiroshi Inaba, Kazunori Matsuura   +3 more
doaj   +1 more source

The Influence of high pressure on the bending rigidity of model membranes [PDF]

, 2015
Curvature is a fundamental lipid membrane property that influences many membrane-mediated biological processes and dynamic soft materials. One of the key parameters that determines the energetics of curvature change is the membrane bending rigidity ...
Brooks, NJ, Ces, O, Cicuta, P, Purushothaman, S   +3 more
core   +2 more sources

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Self-organized spatial targeting of contractile actomyosin rings for synthetic cell division

Nature Communications
A key challenge for bottom-up synthetic biology is engineering a minimal module for self-division of synthetic cells. Actin-based cytokinetic rings are considered a promising structure to produce the forces required for the controlled excision of cell ...
María Reverte-López, Nishu Kanwa, Yusuf Qutbuddin, Viktoriia Belousova, Marion Jasnin, Petra Schwille   +5 more
doaj   +1 more source

Electroformation of Giant Unilamellar Vesicles from Damp Lipid Films with a Focus on Vesicles with High Cholesterol Content

Membranes
Giant unilamellar vesicles (GUVs) are membrane models used to study membrane properties. Electroformation is one of the methods used to produce GUVs. During electroformation protocol, dry lipid film is formed.
Ivan Mardešić, Zvonimir Boban, Marija Raguz   +2 more
doaj   +1 more source

Direct entry of cell-penetrating peptide can be controlled by maneuvering the membrane curvature

Scientific Reports, 2021
A biomembrane's role is to be a barrier for interior cytosol from an exterior environment to execute the cell's normal biological functions. However, a water-soluble peptide called cell-penetrating peptide (CPP) has been known for its ability to directly
Kazutami Sakamoto, Taku Morishita, Kenichi Aburai, Daisuke Ito, Tomohiro Imura, Kenichi Sakai, Masahiko Abe, Ikuhiko Nakase, Shiroh Futaki, Hideki Sakai   +9 more
doaj   +1 more source

A novel minimal in vitro system for analyzing HIV-1 Gag mediated budding

, 2014
A biomimetic minimalist model membrane was used to study the mechanism and kinetics of cell-free in vitro HIV-1 Gag budding from a giant unilamellar vesicle (GUV).
Gill, Sarjeet, Gui, Dong, Gupta, Sharad, Huang, I-Chueh, Mohideen, Umar, Rao, A. L. N., Xu, Jun, Zandi, Roya   +7 more
core   +1 more source

Native silica nanoparticles are powerful membrane disruptors [PDF]

, 2015
Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I., Berthier, Rémy, de Planque, Maurits R.R., Li, Nan   +3 more
core   +1 more source

Reconstitution of an RNA Virus Replicase in Artificial Giant Unilamellar Vesicles Supports Full Replication and Provides Protection for the Double-Stranded RNA Replication Intermediate

Journal of Virology, 2020
Understanding the mechanism of replication of positive-strand RNA viruses, which are major pathogens of plants, animals, and humans, can lead to new targets for antiviral interventions.
Nikolay Kovalev, J. Pogány, P. D. Nagy
semanticscholar   +1 more source