Results 121 to 130 of about 23,127 (230)

Mechanism of cellular uptake of genotoxic silica nanoparticles. [PDF]

, 2012
Mechanisms for cellular uptake of nanoparticles have important implications for nanoparticulate drug delivery and toxicity. We have explored the mechanism of uptake of amorphous silica nanoparticles of 14 nm diameter, which agglomerate in culture medium ...
Brown, AP, Hondow, NS, Jeuken, LJ, Krzemiński, L, Mu, Q, Routledge, MN   +5 more
core   +3 more sources

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, Volume 13, Issue 16, 18 March 2026.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Mixed lipid bilayers with locally varying spontaneous curvature and bending

, 2014
A model of lipid bilayers made of a mixture of two lipids with different average compositions on both leaflets, is developed. A Landau hamiltonian describing the lipid-lipid interactions on each leaflet, with two lipidic fields $\psi_1$ and $\psi_2$, is ...
Destainville, Nicolas, Gueguen, Guillaume, Manghi, Manoel   +2 more
core   +3 more sources

Heat-induced formation of single giant unilamellar vesicles [PDF]

, 2011
Giant unilamellar vesicles (GUVs) are an excellent model system for the investigation of lipid membranes, the study of membrane proteins and ion channels in a biomimetic environment, and in the creation of artificial cells.
Billerit, Celine, Dommersnes, Paul, Jeffries, Gavin, Jesorka, Aldo, Orwar, Owe, Wegrzyn, Ilona   +5 more
core   +1 more source

Forming and loading giant unilamellar vesicles with acoustic jetting

Biomicrofluidics, 2020
Giant unilamellar vesicles (GUVs) are a useful platform for reconstituting and studying membrane-bound biological systems, offering reduced complexity compared to living cells. Several techniques exist to form GUVs and populate them with biomolecules of interest.
Maxim Armstrong, Michael D. Vahey, Thomas P. Hunt, Daniel A. Fletcher   +3 more
openaire   +3 more sources

Curvature‐Assisted Vesicle Explosion Under Light‐Induced Asymmetric Oxidation

Advanced Science
Exposure of cell membranes to reactive oxygen species can cause oxidation of membrane lipids. Oxidized lipids undergo drastic conformational changes, compromising the mechanical integrity of the membrane and causing cell death.
Vinit Kumar Malik, On Shun Pak, Jie Feng
doaj   +1 more source

Permeability of phospholipid membrane for small polar molecules determined from osmotic swelling of giant phospholipid vesicles

, 2012
A method for determining permeability of phospholipid bilayer based on the osmotic swelling of micrometer-sized giant unilamellar vesicles (GUVs) is presented as an alternative to the two established techniques, dynamic light scattering on liposome ...
Al-Awqati, Angelova, Bangham, Bangham, Barry, Bloom, Boroske, Brunner, Carlsen, Cohen, de Gier, de Gier, Diamant, Dimova, Döbereiner, Evans, Finkelstein, Haleva, Heimburg, Heinrich, Hill, Jacobs, Karatekin, Katchalsky, Kedem, Kleinhans, Koslov, Krasteva, Mally, Mally, Mazur, Mazur, Meyer, Missner, Montal, Mueller, Nagle, Onsager, Onsager, Orbach, Overton, Paula, Pavlič, Pencer, Pencer, Peterlin, Peterlin, Peterlin, Pike, Pocivavsek, Popescu, Preston, Rawicz, Sandre, Seifert, Sha'afi, Shoemaker, Tien, Verkman, Walter, Wang, Zade-Oppen   +61 more
core   +1 more source

A functioning artificial secretory cell [PDF]

, 2012
We present an amperometric study of content release from individual vesicles in an artificial secretory cell designed with the minimal components required to carry out exocytosis.
Cans, Ann-Sofie, Höök, Fredrik, Kurczy, Michael E., Simonsson, Lisa, Trouillon, Raphaël   +4 more
core   +1 more source

Probing Interactions between AuNPs/AgNPs and Giant Unilamellar Vesicles (GUVs) Using Hyperspectral Dark-field Microscopy

International Journal of Molecular Sciences, 2018
Noble metallic nanoparticles (NPs) such as gold and silver nanoparticles (AuNPs and AgNPs) have been shown to exhibit anti-tumor effect in anti-angiogenesis, photothermal and radio therapeutics.
A. Bhat, Ke-wei Huan, Tiana Cooks, H. Boukari, Qi Lu   +4 more
semanticscholar   +1 more source

Highly Efficient Protein-free Membrane Fusion: A Giant Vesicle Study.

Biophysical Journal, 2019
Membrane fusion is a ubiquitous process in biology and is a prerequisite for many intracellular delivery protocols relying on the use of liposomes as drug carriers.
R. B. Lira, T. Robinson, R. Dimova, K. Riske   +3 more
semanticscholar   +1 more source