Results 101 to 110 of about 23,127 (230)

Studying antibiotic–membrane interactions via X‐ray diffraction and fluorescence microscopy

FEBS Open Bio, 2015
Antibiotic drug resistance is a serious issue for the treatment of bacterial infection. Understanding the resistance to antibiotics is a key issue for developing new drugs.
Yi-Ting Sun, Ping-Yuan Huang, Cheng-Hao Lin, Kuan-Rong Lee, Ming-Tao Lee   +4 more
doaj   +1 more source

A supramolecular system mimicking the infection process of an enveloped virus through membrane fusion

Scientific Reports, 2023
Membrane fusion is an essential step for the entry of enveloped viruses, such as human immunodeficiency virus and influenza virus, into the host cell, often triggered by the binding of membrane proteins on the viral envelope to host cell membrane ...
Hiroto Furukawa, Yuuna Kimura, Hiroshi Inaba, Kazunori Matsuura   +3 more
doaj   +1 more source

Ion‐ and Temperature‐Programmable Reconfiguration of Subcompartments in Synthetic Cells

ChemBioChem, Volume 27, Issue 8, April 2026.
Spatial organization of subcompartments defines living cells, yet achieving dynamic and reversible compartmentalization remains challenging in bottom‐up synthetic cell design. We report a minimal, protein‐free mechanism in which Mg2+‐mediated intermembrane adhesion reversibly couples neutral large unilamellar vesicle (LUV) subcompartments to negatively
Zexi Xu, Petra Schwille
wiley   +1 more source

Self-organized spatial targeting of contractile actomyosin rings for synthetic cell division

Nature Communications
A key challenge for bottom-up synthetic biology is engineering a minimal module for self-division of synthetic cells. Actin-based cytokinetic rings are considered a promising structure to produce the forces required for the controlled excision of cell ...
María Reverte-López, Nishu Kanwa, Yusuf Qutbuddin, Viktoriia Belousova, Marion Jasnin, Petra Schwille   +5 more
doaj   +1 more source

Electroformation of Giant Unilamellar Vesicles from Damp Lipid Films with a Focus on Vesicles with High Cholesterol Content

Membranes
Giant unilamellar vesicles (GUVs) are membrane models used to study membrane properties. Electroformation is one of the methods used to produce GUVs. During electroformation protocol, dry lipid film is formed.
Ivan Mardešić, Zvonimir Boban, Marija Raguz   +2 more
doaj   +1 more source

Direct entry of cell-penetrating peptide can be controlled by maneuvering the membrane curvature

Scientific Reports, 2021
A biomembrane's role is to be a barrier for interior cytosol from an exterior environment to execute the cell's normal biological functions. However, a water-soluble peptide called cell-penetrating peptide (CPP) has been known for its ability to directly
Kazutami Sakamoto, Taku Morishita, Kenichi Aburai, Daisuke Ito, Tomohiro Imura, Kenichi Sakai, Masahiko Abe, Ikuhiko Nakase, Shiroh Futaki, Hideki Sakai   +9 more
doaj   +1 more source

Reprogramming SREBP1‐dependent lipogenesis and inflammation in high‐risk breast with licochalcone A: A novel path to cancer prevention

International Journal of Cancer, Volume 158, Issue 7, Page 1927-1940, 1 April 2026.
What's new? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan, Elizabeth T. Bartom, Carolina H. Chung, Xingyu Guo, Kyli Berkley, Seyyedmohsen Hosseinibarkooie, Zahra Assadi, Shao Huan Samuel Weng, Raymond Moellering, Oukseub Lee, Ruohui Chen, Wonhwa Cho, Sriram Chandrasekaran, Susan E. Clare, Seema A. Khan   +14 more
wiley   +1 more source

Electroformation in a flow chamber with solution exchange as a means of preparation of flaccid giant vesicles

, 2008
A recently described technique (Estes and Mayer, Biochim. Biophys. Acta 1712 (2005) 152--160) for the preparation of giant unilamellar vesicles (GUVs) in solutions with high ionic strength is examined.
Akashi, Angelova, Angelova, Angelova, Angelova, Bagatolli, Bloom, Božič, Bresseleers, Deamer, Dimova, D’Errico, Estes, Estes, Estes, Evans, Heinrich, Hope, Koslov, Kralj-Iglič, Kuribayashi, Mally, Mally, Mathivet, Morse, Moscho, Needham, Okumura, Olbrich, Orbach, Paula, Paula, Primož Peterlin, Redelmeier, Reeves, Riske, Rodriguez, Taylor, Ternström, Vesna Arrigler, Yamashita   +40 more
core   +1 more source

Native silica nanoparticles are powerful membrane disruptors [PDF]

, 2015
Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I., Berthier, Rémy, de Planque, Maurits R.R., Li, Nan   +3 more
core   +1 more source

DNA Origami Assembly Inside Liposomes via Nanopore‐Mediated DNA Transportation

Small Structures, Volume 7, Issue 4, April 2026.
DNA origami assembly inside giant unilamellar vesicles (GUVs) using externally supplied staple strands is demonstrated. Scaffold DNA is pre‐encapsulated inside GUVs, and staple strands are transported via a pore‐forming membrane protein. Subsequent addition of CaCl2 closes the pores.
Shoji Iwabuchi, Kengo Kurematsu, Kazuya Yokoo, Yusuke Sakai, Yoshihiro Shimizu, Ryuji Kawano   +5 more
wiley   +1 more source