Results 1 to 10 of about 23,483 (183)

Osmotically balanced, large unilamellar liposomes that enable sustained bupivacaine release for prolonged pain relief in in vivo rat models [PDF]

Scientific Reports, 2021
To efficiently prolong analgesic effects, we developed osmotically balanced, large unilamellar liposomes (~ 6 μm in diameter) in which highly concentrated bupivacaine (up to 30 mg/mL) was encapsulated, and their sustained bupivacaine release was highly ...
Hyebin Yoo, Jun Seok Park, Seung Soo Oh, Hyun Kang   +3 more
doaj   +2 more sources

Encapsulation of protein/DNA complexes into unilamellar liposomes via annexin-mediated membrane recruitment and sonication [PDF]

Cell Reports: Methods
Summary: This paper reports an effective protocol to encapsulate native protein/DNA complexes into unilamellar vesicles composed of natural lipids without the use of organic solvents, in physiological buffers, and at low protein/DNA concentrations.
Michael Burger, Finn Brigger, Valeria Mantella, Jean-Christophe Leroux   +3 more
doaj   +2 more sources

Effect of Fragarin on the Cytoplasmic Membrane of the Phytopathogen Clavibacter michiganensis [PDF]

Molecular Plant-Microbe Interactions, 2001
Fragarin, an antibiotic that was isolated and purified from a soluble fraction of strawberry leaves, may be a new type of preformed antimicrobial compound (phytoanticipin).
M. Paula Filippone, Juan C. Diaz-Ricci, Atilio P. Castagnaro, Ricardo N. Farías   +3 more
doaj   +3 more sources

Interaction of unilamellar liposomes with serum lipoproteins and apolipoproteins

Journal of Lipid Research, 1980
The effect of rat whole blood plasma, serum, serum lipoproteins, and apolipoproteins on the stability of unilamellar liposomes prepared with French pressure cell was evaluated by measuring the release of entrapped carboxyfluorescein and by electron ...
L S Guo, R L Hamilton, J Goerke, J N Weinstein, R J Havel   +4 more
doaj   +3 more sources

Structural–Functional Customization of Nanoscale Liposome-in-Liposome Systems: Precision Engineering Methodology and Artificial-Intelligence-Driven Design Prospects [PDF]

Research
Liposome-in-liposome systems with multicompartment structures offer advantages in structural complexity and functional programmability, but their application is limited by poor controllability in conventional fabrication.
Liutao Hu, Jianfeng Cai, Chao Lu
doaj   +2 more sources

Caspase-8 binding to cardiolipin in giant unilamellar vesicles provides a functional docking platform for bid [PDF]

, 2013
Caspase-8 is involved in death receptor-mediated apoptosis in type II cells, the proapoptotic programme of which is triggered by truncated Bid. Indeed, caspase-8 and Bid are the known intermediates of this signalling pathway.
AH Stegh, AH Stegh, AJ Garcia-Saez, AJ Garcia-Saez, AM Chinnaiyan, Ana-Jesus García-Sáez, B Apellaniz, B Leber, Beate Klösgen, Boris Zhivotovsky, C Scaffidi, D Ardail, D Ardail, D Chandra, D Marsh, D Marsh, D Needham, DW Chang, E Evans, E Krieghoff, E van den Brink-van der Laan, EE Varfolomeev, Eyal Gottlieb, F Gonzalvez, F Gonzalvez, F Gonzalvez, F Gonzalvez, FC Kischkel, François Gonzalvez, G Kroemer, GC Shearman, H Zhang, HR Stennicke, J Zha, Jesus Ayala-Sanmartin, JF Lovell, JH Li, JP Medema, K Milovic-Holm, KH Lee, KM Boatright, L Mathivet, Liberty François-Moutal, M Lamblet, M Lutter, M Lutter, M Muzio, M Muzio, MA Hughes, Mark Perry, MI Angelova, MO Hengartner, MP Boldin, N Keller, Olivier Jalmar, P Juo, P Ratanabanangkoon, Patrice X. Petit, Petra Schwille, PJ Jost, RF Epand, S Zhang, T Granjon, T Kuwana, T Parasassi, Thierry Granjon, VA Torres, VA Torres, W Helfrich, W Rawicz, WC Yeh, X Luo, Y Zaltsman, ZT Schug   +73 more
core   +15 more sources

Application of Various Types of Liposomes in Drug Delivery Systems [PDF]

Advanced Pharmaceutical Bulletin, 2017
Liposomes, due to their various forms, require further exploration. These structures can deliver both hydrophilic and hydrophobic drugs for cancer, antibacterial, antifungal, immunomodulation, diagnostics, ophtalmica, vaccines, enzymes and genetic ...
Mehran Alavi, Naser Karimi, Mohsen Safaei   +2 more
doaj   +1 more source

A Simple and Straightforward Approach for Generating Small, Stable, Homogeneous, Unilamellar 1-Palmitoyl 2-Oleoyl Phosphatidylcholine (POPC) Bilayer Vesicles

Bio-Protocol, 2021
Various methods have been developed to generate phosphoglyceride liposomes. Approaches resulting in homogeneous populations of unilamellar bilayer vesicles are generally preferred to mimic various cell membrane situations, as well as to optimize aqueous ...
Yong Gao, Le My Le, Amer Alam, Rhoderick Brown   +3 more
doaj   +1 more source

A Fluorescence Dequenching-based Liposome Leakage Assay to Measure Membrane Permeabilization by Pore-forming Proteins

Bio-Protocol, 2021
Pore-forming toxins (PFTs) have been discovered in a wide range of organisms. Their functions are essential to the survival or virulence of many species. PFTs often interact with lipid membranes. Large unilamellar vesicles (LUV), also known as liposomes,
Javier Aguilera, Salvador Vazquez-Reyes, Jianjun Sun   +2 more
doaj   +1 more source

Nanoporous silica-based protocells at multiple scales for designs of life and nanomedicine. [PDF]

, 2015
Various protocell models have been constructed de novo with the bottom-up approach. Here we describe a silica-based protocell composed of a nanoporous amorphous silica core encapsulated within a lipid bilayer built by self-assembly that provides for ...
Brinker, C Jeffrey, Jakobsson, Eric, Sun, Jie, Wang, Yingxiao   +3 more
core   +5 more sources