Results 21 to 30 of about 23,528 (221)

Native silica nanoparticles are powerful membrane disruptors [PDF]

, 2015
Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I., Berthier, Rémy, de Planque, Maurits R.R., Li, Nan   +3 more
core   +1 more source

Distribution and Inhibition of Liposomes on Staphylococcus aureus and Pseudomonas aeruginosa Biofilm. [PDF]

PLoS ONE, 2015
Staphylococcus aureus and Pseudomonas aeruginosa are major pathogens in chronic rhinosinusitis (CRS) and their biofilms have been associated with poorer postsurgical outcomes. This study investigated the distribution and anti-biofilm effect of cationic (+
Dong Dong, Nicky Thomas, Benjamin Thierry, Sarah Vreugde, Clive A Prestidge, Peter-John Wormald   +5 more
doaj   +1 more source

Octanol-assisted liposome assembly on chip

Nature Communications, 2016
A broad application of liposomes calls for high throughout techniques to produce them in a controlled and fast manner. Here, Deshpande et al. show a microfluidic approach using alcohol-based lipid-carrying material to generate monodisperse and ...
Siddharth Deshpande, Yaron Caspi, Anna E. C. Meijering, Cees Dekker   +3 more
doaj   +1 more source

Unilamellar liposomes made with the French pressure cell: a simple preparative and semiquantitative technique

Journal of Lipid Research, 1980
A simple, rapid, and almost quantitative technique is described for the preparation of 1-40 ml of homogeneous unilamellar liposomes from dilute or concentrated aqueous suspensions of egg phosphatidylcholine.
R L Hamilton, Jr, J Goerke, L S Guo, M C Williams, R J Havel   +4 more
doaj   +1 more source

Cell-Penetrating Peptides-Based Liposomal Delivery System Enhanced Immunogenicity of Peptide-Based Vaccine against Group A Streptococcus

Vaccines, 2021
Peptide-based vaccine development represents a highly promising strategy for preventing Group A Streptococcus (GAS) infection. However, these vaccines need to be administered with the help of a delivery system and/or immune adjuvant.
Jieru Yang, Farrhana Firdaus, Armira Azuar, Zeinab G. Khalil, Nirmal Marasini, Robert J. Capon, Waleed M. Hussein, Istvan Toth, Mariusz Skwarczynski   +8 more
doaj   +1 more source

In vivo stability of ester- and ether-linked phospholipid-containing liposomes as measured by perturbed angular correlation spectroscopy [PDF]

, 1988
To evaluate liposome formulations for use as intracellular sustained-release drug depots, we have compared the uptake and degradation in rat liver and spleen of liposomes of various compositions, containing as their bulk phospholipid an ether-linked ...
Baldeschwieler, John D., Derksen, Johannes T. P., Scherphof, Gerrit L.   +2 more
core   +1 more source

Effects of Gabaergic phenols on phospholipid bilayers as evaluated by 1H-NMR [PDF]

, 2013
The phenols propofol and thymol, and lately carvacrol, eugenol and chlorothymol, have been shown to act as positive allosteric modulators on GABAA receptor, which is the main inhibitory receptor of the central nervous system.
Fraceto, Leonardo Fernandes, Garcia, Daniel Asmed, Paula, Eneida de, Perillo, Maria Angelica, Reiner, Gabriela de Las Nieves   +4 more
core   +1 more source

Small cationic DDA:TDB liposomes as protein vaccine adjuvants obviate the need for TLR agonists in inducing cellular and humoral responses.

PLoS ONE, 2012
Most subunit vaccines require adjuvants in order to induce protective immune responses to the targeted pathogen. However, many of the potent immunogenic adjuvants display unacceptable local or systemic reactogenicity.
Anita Milicic, Randip Kaur, Arturo Reyes-Sandoval, Choon-Kit Tang, Jared Honeycutt, Yvonne Perrie, Adrian V S Hill   +6 more
doaj   +1 more source

Bleomycin-induced trans lipid formation in cell membranes and in liposome models [PDF]

, 2015
Cell cultures of NTera-2 cells incubated with bleomycin and liposomes as biomimetic models of cell membranes were used for examining some novel aspects of drug-metal induced reactivity with unsaturated lipids under oxidative conditions. In cell cultures,
Barata Vallejo, Sebastian, Chatgilialoglu, Chryssostomos, Cort, Aysegul, Ferreri, Carla, Ozben, Tomris, Sansone, Anna   +5 more
core   +1 more source

Thermophoretic migration of vesicles depends on mean temperature and head group chemistry

Nature Communications, 2017
Thermal gradients are shown to provide a robust and chemically specific driving force to liposomes. Here the authors show controlled direction of migration of unilamellar lipid vesicles by varying the temperature in the suspension and the exposed polar ...
Emma L. Talbot, Jurij Kotar, Lucia Parolini, Lorenzo Di Michele, Pietro Cicuta   +4 more
doaj   +1 more source