Results 31 to 40 of about 14,273 (226)

Tailoring the Lamellarity of Liposomes Prepared by Dual Centrifugation

Pharmaceutics, 2023
Dual centrifugation (DC) is a new and versatile technique for the preparation of liposomes by in-vial homogenization of lipid-water mixtures. Size, size distribution, and entrapping efficiencies are strongly dependent on the lipid concentration during DC-
Jonas K. Koehler, Lars Gedda, Leonie Wurster, Johannes Schnur, Katarina Edwards, Heiko Heerklotz, Ulrich Massing   +6 more
doaj   +1 more source

Encapsulation of ropivacaine in a combined (donor-acceptor, ionic-gradient) liposomal system promotes extended anesthesia time. [PDF]

PLoS ONE, 2017
Ropivacaine is a local anesthetic with similar potency but lower systemic toxicity than bupivacaine, the most commonly used spinal anesthetic. The present study concerns the development of a combined drug delivery system for ropivacaine, comprised of two
Camila Morais Gonçalves da Silva, Michelle Franz-Montan, Cíntia Elisabeth Gomez Limia, Lígia Nunes de Morais Ribeiro, Mário Antônio Braga, Viviane Aparecida Guilherme, Camila Batista da Silva, Bruna Renata Casadei, Cíntia Maria Saia Cereda, Eneida de Paula   +9 more
doaj   +1 more source

Octanol-assisted liposome assembly on chip

Nature Communications, 2016
A broad application of liposomes calls for high throughout techniques to produce them in a controlled and fast manner. Here, Deshpande et al. show a microfluidic approach using alcohol-based lipid-carrying material to generate monodisperse and ...
Siddharth Deshpande, Yaron Caspi, Anna E. C. Meijering, Cees Dekker   +3 more
doaj   +1 more source

Formation of Giant Unilamellar Proteo-Liposomes by Osmotic Shock [PDF]

Langmuir, 2015
Giant unilamellar vesicles (GUVs), composed of a phospholipid bilayer, are often used as a model system for cell membranes. However, the study of proteo-membrane interactions in this system is limited as the incorporation of integral and lipid-anchored proteins into GUVs remains challenging.
Motta, Isabelle, Gohlke, Andrea, Adrien, Vladimir, Li, Feng, Gardavot, Hélène, Rothman, James, Pincet, Frederic   +6 more
openaire   +3 more sources

Distribution and Inhibition of Liposomes on Staphylococcus aureus and Pseudomonas aeruginosa Biofilm. [PDF]

PLoS ONE, 2015
Staphylococcus aureus and Pseudomonas aeruginosa are major pathogens in chronic rhinosinusitis (CRS) and their biofilms have been associated with poorer postsurgical outcomes. This study investigated the distribution and anti-biofilm effect of cationic (+
Dong Dong, Nicky Thomas, Benjamin Thierry, Sarah Vreugde, Clive A Prestidge, Peter-John Wormald   +5 more
doaj   +1 more source

Unilamellar liposomes made with the French pressure cell: a simple preparative and semiquantitative technique

Journal of Lipid Research, 1980
A simple, rapid, and almost quantitative technique is described for the preparation of 1-40 ml of homogeneous unilamellar liposomes from dilute or concentrated aqueous suspensions of egg phosphatidylcholine.
R L Hamilton, Jr, J Goerke, L S Guo, M C Williams, R J Havel   +4 more
doaj   +1 more source

Cell-Penetrating Peptides-Based Liposomal Delivery System Enhanced Immunogenicity of Peptide-Based Vaccine against Group A Streptococcus

Vaccines, 2021
Peptide-based vaccine development represents a highly promising strategy for preventing Group A Streptococcus (GAS) infection. However, these vaccines need to be administered with the help of a delivery system and/or immune adjuvant.
Jieru Yang, Farrhana Firdaus, Armira Azuar, Zeinab G. Khalil, Nirmal Marasini, Robert J. Capon, Waleed M. Hussein, Istvan Toth, Mariusz Skwarczynski   +8 more
doaj   +1 more source

Small cationic DDA:TDB liposomes as protein vaccine adjuvants obviate the need for TLR agonists in inducing cellular and humoral responses.

PLoS ONE, 2012
Most subunit vaccines require adjuvants in order to induce protective immune responses to the targeted pathogen. However, many of the potent immunogenic adjuvants display unacceptable local or systemic reactogenicity.
Anita Milicic, Randip Kaur, Arturo Reyes-Sandoval, Choon-Kit Tang, Jared Honeycutt, Yvonne Perrie, Adrian V S Hill   +6 more
doaj   +1 more source

Thermophoretic migration of vesicles depends on mean temperature and head group chemistry

Nature Communications, 2017
Thermal gradients are shown to provide a robust and chemically specific driving force to liposomes. Here the authors show controlled direction of migration of unilamellar lipid vesicles by varying the temperature in the suspension and the exposed polar ...
Emma L. Talbot, Jurij Kotar, Lucia Parolini, Lorenzo Di Michele, Pietro Cicuta   +4 more
doaj   +1 more source

Enrichment of Artemia nauplii in vitamin A, vitamin C and methionine using liposomes [PDF]

, 2007
Several types of liposomes were used to enrich Artemia nauplii in vitamin A, vitamin C and free methionine. In a first experiment, unilamellar liposomes formulated with krill phospholipid extract and retinyl palmitate demonstrated their capability to ...
Hontoria, Francisco, Navarro, Juan Carlos, Monroig, Oscar, Amat, Francisco   +3 more
core   +1 more source