Results 51 to 60 of about 12,810 (206)

Uniform Microscale Thermoresponsive Liposomes for Controlled Release Above Body Temperature

Small, EarlyView.
Uniform thermoresponsive liposomes are generated using a scalable double‐emulsion microfluidic approach coupled with accelerated solvent extraction. The resulting liposomes remain stable at physiological temperature but undergo abrupt rupture and cargo release at 41°C–45°C, providing a versatile platform for thermally triggered controlled release in ...
S. Morteza Mousavi, Yang Zhang, Elvis Pandzic, David W. Inglis, Megan S. Lord, Robert A. Taylor, Ming Li   +6 more
wiley   +1 more source

Niosome as a promising tool for increasing the effectiveness of anti-inflammatory compounds

EXCLI Journal : Experimental and Clinical Sciences
Niosomes are drug delivery systems with widespread applications in pharmaceutical research and the cosmetic industry. Niosomes are vesicles of one or more bilayers made of non-ionic surfactants, cholesterol, and charge inducers.
Mohammad Saleh Fadaei, Mohammad Reza Fadaei, Amir Emad Kheirieh, Pouria Rahmanian-Devin, Mohammad Mahdi Dabbaghi, Kiarash Nazari Tavallaei, Abouzar Shafaghi, Hooman Hatami, Vafa Baradaran Rahimi, Ali Nokhodchi, Vahid Reza Askari   +10 more
doaj   +1 more source

Reduced colony‐stimulating factor 1 receptor expression in myeloid cells has limited impact on chronic lymphocytic leukaemia progression

British Journal of Haematology, EarlyView.
Summary Targeting the colony‐stimulating factor 1 receptor (CSF1R) to remove tumour‐associated macrophages is being explored as cancer therapy. This strategy may be relevant for chronic lymphocytic leukaemia (CLL), which strongly depends on support from myeloid cells.
Natascha Rosen, Guillermo Rodriguez‐Real, Alexander F. vom Stein, Luca D. Schreurs, Trong‐Hieu Nguyen, Viktoria Kohlhas, Thanh‐Tung Truong, Maximilian Koch, Sebastian Reinartz, Sumiya Iqbal, Shaista Ilyas, Sanjay Mathur, Nina Reinart, Phuong‐Hien Nguyen, Michael Hallek   +14 more
wiley   +1 more source

Cholesterol protects phosphatidylcholine liposomes from N,N-dimethyldodekanamine N-oxide influence

Acta Chimica Slovenica, 2015
The interaction of N,N-dimethyldodekanamine N-oxide (C12(CH3)2NO) with egg yolk phosphatidylcholine (EYPC) liposomes containing cholesterol (CHOL) in molar ratios nCHOL:nEYPC = 0-0,8 was studied.
Silvia Huláková, Jana Gallová, Ferdinand Devínsky   +2 more
doaj   +1 more source

Monascus Red Pigment Liposomes: Microstructural Characteristics, Stability, and Anticancer Activity

Foods, 2023
Monascus red pigments (MRPs), which are a kind of natural colorant produced by Monascus spp., are widely used in the food and health supplements industry but are not very stable during processing and storage.
Pengcheng Long, Lisha Zhu, Huafa Lai, Suyin Xu, Xingxing Dong, Yanchun Shao, Liling Wang, Shuiyuan Cheng, Gang Liu, Jingren He, Yi He   +10 more
doaj   +1 more source

The sorting nexin Snx21 promotes flotillin‐mediated endocytosis

The FEBS Journal, EarlyView.
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs, Enikő Lakatos, Dalma Feil‐Börcsök, Gábor Juhász, Regina Mező, Asha Kiran Maddali, András Blastyák, Aladár Pettkó‐Szandtner, Hajnalka Laczkó‐Dobos, Gábor Juhász   +9 more
wiley   +1 more source

Liposome Disruption Assay to Examine Lytic Properties of Biomolecules

Bio-Protocol, 2017
Proteins may have three dimensional structural or amino acid features that suggest a role in targeting and disrupting lipids within cell membranes. It is often necessary to experimentally investigate if these proteins and biomolecules are able to disrupt
John Jimah, Paul Schlesinger, Niraj Tolia   +2 more
doaj   +1 more source

Large unilamellar liposomes with low uptake into the reticuloendothelial system

FEBS Letters, 1987
Particulate drug carriers, including liposomes, are rapidly removed from blood by cells of the reticuloendothelial system (RES) with resulting adverse effects on this important host defense system. In order to overcome this and other major disadvantages of liposomes, we have altered liposome composition in an effort to achieve prolonged circulation ...
Allen, T.M., Chonn, A.
openaire   +2 more sources

Efficacy Assessment of Montanide GEL 02 PR and Liposome‐Based Encapsulation as Adjuvants for an FrpA Subunit Vaccine Against Photobacteriosis in Solea senegalensis

Journal of Fish Diseases, EarlyView.
ABSTRACT Photobacteriosis is a major threat to marine aquaculture, and the siderophore transporter FrpA represents a promising target for effective subunit vaccine development. In this study, we evaluated Montanide GEL 02 PR and phosphatidylcholine‐based liposomes as aqueous and safer alternatives to Freund's adjuvant for an FrpA‐based subunit vaccine ...
Marta A. Lages, Miguel Balado, Abel M. Forero, Lucía Ageitos, Jaime Rodríguez, Carlos Jiménez, Manuel L. Lemos, Beatriz Magariños   +7 more
wiley   +1 more source

A nano-Liposomal formulation potentiates antioxidant, anti-inflammatory, and fibrinolytic activities of Allolobophora caliginosa coelomic fluid: formulation and characterization

BMC Biotechnology, 2023
Background Coelomic fluid, a pharmacologically active compound in earthworms, exhibits a range of biological activities, including antioxidant, anti-inflammatory, and anticancer.
Asmaa E. Farouk, Sohair R. Fahmy, Amel M. Soliman, Sherif Abdelaziz Ibrahim, Shimaa A. Sadek   +4 more
doaj   +1 more source