Results 71 to 80 of about 12,810 (206)

Formation of homogeneous unilamellar liposomes from an interdigitated matrix

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2005
Phospholipid-ethanol-aqueous mixtures containing bilayer-forming lipids and 20-50 wt.% of water form viscous gels. Further hydration of these gels results in the formation of liposomes whose morphology depends upon the lipid type. Upon hydration of gels containing mixtures of the lipids 1-palmitoyl-2-oleoyl-phosphatidylcholine (POPC) and 1-palmitoyl-2 ...
Polozova, Alla, Li, Xingong, Shangguan, Tong, Meers, Paul, Schuette, Daniel R., Ando, Nozomi, Gruner, Sol M., Perkins, Walter R.   +7 more
openaire   +2 more sources

Microenvironment‐Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges

Small Science, Volume 6, Issue 8, August 2026.
Microenvironment‐responsive drug delivery systems overcome ocular physiological barriers by responding to temperature, pH, ions, reactive oxygen species, and enzymes. This review bridges material design, performance evaluation, and clinical translation, offering actionable insights for treating dry eye disease, infectious keratitis, and corneal ...
Jiamin Liu, Liangbo Chen, Yao Fu, Siyi Zhang   +3 more
wiley   +1 more source

Silibinin-Loaded Liposomes: The Influence of Modifications on Physicochemical Characteristics, Stability, and Bioactivity Associated with Dermal Application

Pharmaceutics
Background/Objectives: The aims of the presented study were the development of four types of silibinin-loaded liposomes (multilamellar liposomes—MLVs, sonicated small unilamellar liposomes—SUVs, UV-irradiated liposomes, and lyophilized liposomes) and ...
Amjed Abdullah Karkad, Andrea Pirković, Milena Milošević, Bojan Stojadinović, Katarina Šavikin, Aleksandar Marinković, Aleksandra A. Jovanović   +6 more
doaj   +1 more source

Light‐Activated Communication Between Synthetic and Living Cells via Photoresponsive Membranes

ChemBioChem, Volume 27, Issue 14, 29 July 2026.
Light‐triggered membrane rupture of SCs enables controlled release of adenosine triphosphate (ATP) and histamine, which activate purinergic and histaminergic signaling in HeLa cells, leading to intracellular Ca2+ mobilization. This biomimetic communication platform provides a simple strategy for engineering remotely controlled chemical signaling ...
Roberto Barbaro, Paola Albanese, Matilde Colella, Davide Lattarulo, Samrat Saha, Jack L.‐Y. Chen, Fabio Mavelli, Federico Rossi, Emiliano Altamura   +8 more
wiley   +1 more source

Diffusion of hydrogen peroxide across DPPC large unilamellar liposomes

Chemistry and Physics of Lipids, 2012
The decomposition of hydrogen peroxide catalyzed by catalase entrapped in the pool of dipalmitoylphosphatidyl choline unilamellar liposomes has been studied. The rate of the process was evaluated by following the production of oxygen as a function of time.
Abuin, Elsa, Lissi, Eduardo, Ahumada, Manuel   +2 more
openaire   +4 more sources

C‐Terminal Nucleobase Modification Amplifies Peptide‐Mediated Liposome Fusion

Chemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
Let's come together right now. Cationic peptides are known to promote aggregation of negatively charged liposomes through electrostatic interaction. The process is reversible: once neutrality is achieved, liposomes disaggregate. Here, we demonstrate that end‐capping peptides with nucleobases turns the process into irreversible fusion.
Laura Morbiato, Giacomo Bettin, Chiara Dalla Torre, Lorenzo Stella, Marta De Zotti   +4 more
wiley   +1 more source

Surfactant protein-A nanobody-conjugated liposomes loaded with methylprednisolone increase lung-targeting specificity and therapeutic effect for acute lung injury

Drug Delivery, 2017
The advent of nanomedicine requires novel delivery vehicles to actively target their site of action. Here, we demonstrate the development of lung-targeting drug-loaded liposomes and their efficacy, specificity and safety.
Nan Li, Dong Weng, Shan-Mei Wang, Yuan Zhang, Shan-Shan Chen, Zhao-Fang Yin, Jiali Zhai, Judy Scoble, Charlotte C. Williams, Tao Chen, Hui Qiu, Qin Wu, Meng-Meng Zhao, Li-Qin Lu, Xavier Mulet, Hui-Ping Li   +15 more
doaj   +1 more source

PEO-b-PPO star-shaped polymers enhance the structural stability of electrostatically coupled liposome/polyelectrolyte complexes.

PLoS ONE, 2019
We propose a strategy to counteract the salt-driven disassembly of multiliposomal complexes made by electrostatic co-assembly of anionic small unilamellar liposomes and cationic star-shaped polyelectrolytes (made of quaternized poly(dimethylaminoethyl ...
Camille E Pinguet, Esther Ryll, Alexander A Steinschulte, Jón M Hoffmann, Monia Brugnoni, Andrey Sybachin, Dominik Wöll, Alexander Yaroslavov, Walter Richtering, Felix A Plamper   +9 more
doaj   +1 more source

Preparation of submicron unilamellar liposomes by freeze-drying double emulsions

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2006
A novel method is described for the preparation of sterile submicron unilamellar liposomes. The method is based on the lyophilization of double emulsions containing disaccharides as lyoprotectants in both the inner and outer aqueous phase. Using various phospholipids or mixtures of lipids as emulsifiers, the double emulsions can be prepared by a two ...
Wang, Ting, Deng, Yingjie, Geng, Yehui, Gao, Zibin, Zou, Jianping, Wang, Zhixuan   +5 more
openaire   +2 more sources

Generation of Giant Unilamellar Liposomes Containing Biomacromolecules at Physiological Intracellular Concentrations using Hypertonic Conditions [PDF]

, 2014
Kei Fujiwara, Miho Yanagisawa
openalex   +1 more source