Results 131 to 140 of about 26,375 (226)

High-Efficiency Drug Loading in Lipid Vesicles by MEMS-Driven Gigahertz Acoustic Streaming

Micromachines
Drug carriers hold significant promise for precision medicine but face persistent challenges in balancing high encapsulation efficiency with structural preservation during active loading.
Bingxuan Li, Haopu Wang, Zhen Wang, Huikai Xie, Yao Lu   +4 more
doaj   +1 more source

Membrane Protrusion Coarsening and Nanotubulation within Giant Unilamellar Vesicles

Journal of the American Chemical Society, 2011
Hydrophobic side groups on a stimuli-responsive polymer, encapsulated within a single giant unilamellar vesicle, enable membrane attachment during compartment formation at elevated temperatures. We thermally modulated the vesicle through implementation of an IR laser via an optical fiber, enabling localized directed heating.
Węgrzyn, Ilona, Jeffries, Gavin D.M., Nagel, Birgit, Katterle, Martin, Gerrard, Simon R., Brown, Tom, Orwar, Owe, Jesorka, Aldo   +7 more
openaire   +3 more sources

Vesicle dynamics in elongation flow: Wrinkling instability and bud formation

, 2007
We present experimental results on the relaxation dynamics of vesicles subjected to a time-dependent elongation flow. We observed and characterized a new instability, which results in the formation of higher order modes of the vesicle shape (wrinkles ...
Enrico Segre, Vasiliy Kantsler, Victor Steinberg, W. Rawicz   +3 more
core   +1 more source

Synthesis of Gb3 Glycosphingolipids with Labeled Head Groups: Distribution in Phase‐Separated Giant Unilamellar Vesicles

Angewandte Chemie, 2019
The receptor lipid Gb3 is responsible for the specific internalization of Shiga toxin (STx) into cells. The head group of Gb3 defines the specificity of STx binding, and the backbone with different fatty acids is expected to influence its localization ...
Jeremias Sibold, K. Kettelhoit, Loan Vuong, Fangyuan Liu, D. Werz, C. Steinem   +5 more
semanticscholar   +1 more source

Isothermal amplification of specific DNA molecules inside giant unilamellar vesicles.

Chemical Communications, 2019
An isothermal amplification circuit for specific DNA molecules was implemented in giant unilamellar vesicles. Using this circuit, over 5000-fold amplification of output DNAs was achieved, and the amplification behaviour depended on the concentration of ...
Yusuke Sato, K. Komiya, I. Kawamata, S. Murata, S. Nomura   +4 more
semanticscholar   +1 more source

Mixed lipid bilayers with locally varying spontaneous curvature and bending

, 2014
A model of lipid bilayers made of a mixture of two lipids with different average compositions on both leaflets, is developed. A Landau hamiltonian describing the lipid-lipid interactions on each leaflet, with two lipidic fields $\psi_1$ and $\psi_2$, is ...
Destainville, Nicolas, Gueguen, Guillaume, Manghi, Manoel   +2 more
core   +3 more sources

Permeability of phospholipid membrane for small polar molecules determined from osmotic swelling of giant phospholipid vesicles

, 2012
A method for determining permeability of phospholipid bilayer based on the osmotic swelling of micrometer-sized giant unilamellar vesicles (GUVs) is presented as an alternative to the two established techniques, dynamic light scattering on liposome ...
Al-Awqati, Angelova, Bangham, Bangham, Barry, Bloom, Boroske, Brunner, Carlsen, Cohen, de Gier, de Gier, Diamant, Dimova, Döbereiner, Evans, Finkelstein, Haleva, Heimburg, Heinrich, Hill, Jacobs, Karatekin, Katchalsky, Kedem, Kleinhans, Koslov, Krasteva, Mally, Mally, Mazur, Mazur, Meyer, Missner, Montal, Mueller, Nagle, Onsager, Onsager, Orbach, Overton, Paula, Pavlič, Pencer, Pencer, Peterlin, Peterlin, Peterlin, Pike, Pocivavsek, Popescu, Preston, Rawicz, Sandre, Seifert, Sha'afi, Shoemaker, Tien, Verkman, Walter, Wang, Zade-Oppen   +61 more
core   +1 more source

Measuring the Effect of Tension on Lipid Membrane Viscosity [PDF]

, 2015
39 pages. A thesis presented to the Department of Physics and the Clark Honors College of the University of Oregon in partial fulfillment of the requirements for degree of Bachelor of Science, Spring 2015.The fluidity of the lipid membrane is essential ...
Reyer, Matthew
core  

Benefits of Combined Fluorescence Lifetime Imaging Microscopy and Fluorescence Correlation Spectroscopy for Biomedical Studies Demonstrated by Using a Liposome Model System

Biophysica
Drug delivery systems play a pivotal role in targeted pharmaceutical transport and controlled release at specific sites. Liposomes, commonly used as drug carriers, constitute a fundamental part of these systems.
Kristina Bruun, Hans-Gerd Löhmannsröben, Carsten Hille   +2 more
doaj   +1 more source

Study of macroscopic and microscopic properties of liposomes produced using microfluidic methods [PDF]

, 2019
For the last decades, lipid vesicles or liposomes, vesicles formed by a bilayer of amphiphilic lipids, have been used as a toy model for studying the cell membrane and for applications in cosmetics and drug delivery.
Rojo González, Javier
core