Results 71 to 80 of about 347,263 (150)

GIANT UNILAMELLAR VESICLES FOR PEPTIDE-MEMBRANE INTERACTION STUDIES USING FLUORESCENCE MICROSCOPY

, 2020
Vesicles are a type of biological or biomimetic particle consisting of one or more often spherical bilayers made up of amphipathic molecules, creating a closed system.
Nilsson, Martin
core   +2 more sources

Tuning Membrane Binding and Lipid Phase Preference of DNA Nanostructures via Synergistic Multi‐Lipidation

ChemSystemsChem, Volume 8, Issue 5, September 2026.
DNA origami nanostructures functionalized with lipophilic anchors of distinct hydrophobicity reveal synergistic effects on membrane binding and phase‐specific localization. Weak anchors, although insufficient for binding alone, enhance membrane association and govern selective phase partitioning when combined with strong anchors, establishing multi ...
Subhasini Singh, Henri G. Franquelim
wiley   +1 more source

Reversible Photocontrol of mRNA Synthesis and Cleavage for mRNA Concentration Switching Inside Artificial Cells

ChemSystemsChem, Volume 8, Issue 5, September 2026.
Azobenzene‐modified hairpin DNA (AzoPinDNA) controls transcription and mRNA cleavage. While visible light (vis) allows transcription by T7 RNA polymerase, UV irradiation triggers AzoPinDNA to open and hybridize with mRNA, inducing site‐specific cleavage by RNase H and inhibiting transcription.
Daichi Iwata, Keiji Murayama, Ken Komiya, Hideaki T. Matsubayashi, Keita Abe, Hiroyuki Asanuma, Satoshi Murata, Shin‐ichiro M. Nomura   +7 more
wiley   +1 more source

Fluorescence Microscopy to Study Pressure Between Lipids in Giant Unilamellar Vesicles [PDF]

, 2007
The authors developed a technique to apply high hydrostatic pressure to giant unilamellar vesicles and to directly observe the consequent structural changes with two-photon fluorescence microscopy imaging using high numerical aperture oil-immersion ...
Anna Celli, Claudia Y. C. Lee, Enrico Gratton, Lee, Claudia YC, Gratton, Enrico, Celli, Anna   +5 more
core   +1 more source

Reduced colony‐stimulating factor 1 receptor expression in myeloid cells has limited impact on chronic lymphocytic leukaemia progression

British Journal of Haematology, Volume 209, Issue 3, Page 939-952, September 2026.
Summary Targeting the colony‐stimulating factor 1 receptor (CSF1R) to remove tumour‐associated macrophages is being explored as cancer therapy. This strategy may be relevant for chronic lymphocytic leukaemia (CLL), which strongly depends on support from myeloid cells.
Natascha Rosen, Guillermo Rodriguez‐Real, Alexander F. vom Stein, Luca D. Schreurs, Trong‐Hieu Nguyen, Viktoria Kohlhas, Thanh‐Tung Truong, Maximilian Koch, Sebastian Reinartz, Sumiya Iqbal, Shaista Ilyas, Sanjay Mathur, Nina Reinart, Phuong‐Hien Nguyen, Michael Hallek   +14 more
wiley   +1 more source

Integrating microfluidic generation, handling and analysis of biomimetic giant unilamellar vesicles [PDF]

, 2014
The key roles played by phospholipids in many cellular processes, has led to the development of model systems, to explore both lipid–lipid and lipid–peptide interactions.
Tassieri, M., Paterson, D. J., Wilson, R., Cooper, J. M., Reboud, J.   +4 more
core   +1 more source

Environmental Impact of Synthetic Cell Technology: Review of Life Cycle Assessment Data for Feedstocks and Production Methods

ChemBioChem, Volume 27, Issue 15, 14 August 2026.
Synthetic cells are positioned as enablers of green technology. But what is known about the environmental impact of synthetic cell production? In this review, we examine drivers of greenhouse gas emissions, toxicity, and other environmental impact categories of synthetic cell components.
Christina Hopf, Mehdi Ravandeh, Jan Steinkühler   +2 more
wiley   +1 more source

Study of the Interaction of a Novel Semi-Synthetic Peptide with Model Lipid Membranes

Membranes, 2020
Most linear peptides directly interact with membranes, but the mechanisms of interaction are far from being completely understood. Here, we present an investigation of the membrane interactions of a designed peptide containing a non-natural, synthetic ...
Lucia Sessa, Simona Concilio, Peter Walde, Tom Robinson, Petra S. Dittrich, Amalia Porta, Barbara Panunzi, Ugo Caruso, Stefano Piotto   +8 more
doaj   +1 more source

Repurposing a Lipid Droplet‐Associated Algal Protein as a Biosensor for Phosphatidic Acid

Advanced Sensor Research, Volume 5, Issue 8, August 2026.
The DTH1 lipid binding domain (DTH1LBD) binds to lipid membranes containing phosphatidic acid (PA). Its N‐terminal amphipathic helices are sufficient for this association and, when labeled with solvatochromic fluorophores, can serve as in vitro PA biosensors.
Bilge Ercan, Nian Kee Tan, Julia Lin, Jingyao You, Stephen M. Butler, Katrina A. Jolliffe   +5 more
wiley   +1 more source

Coupled Effects of Mechanics, Geometry, and Chemistry on Bio-Membrane Behavior [PDF]

, 2013
Lipid bilayer membranes are models for cell membranes--the structure that helps regulate cell function. Cell membranes are heterogeneous, and the coupling between composition and shape gives rise to complex behaviors that are important to regulation ...
Giang, Ha Thanh
core   +1 more source