Results 91 to 100 of about 2,070,727 (280)

Gene Repertoire of Amoeba-Associated Giant Viruses [PDF]

open access: yesIntervirology, 2010
<i>Acanthamoeba polyphaga mimivirus</i>, Marseillevirus, and <i>Sputnik</i>, a virophage, are intra-amoebal viruses that have been isolated from water collected in cooling towers. They have provided fascinating data and have raised exciting questions about viruses definition and evolution.
Philippe, Colson, Didier, Raoult
openaire   +2 more sources

Multiphysics‐Driven Assembly of Biomimetic Vesicles

open access: yesAdvanced Materials, EarlyView.
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko   +16 more
wiley   +1 more source

Clinical features of varicella-zoster virus infection [PDF]

open access: yes, 2018
Varicella-zoster virus (VZV) is a pathogenic human herpes virus that causes varicella (chickenpox) as a primary infection, following which it becomes latent in peripheral ganglia.
Gershon, Anne A., Kennedy, Peter G.E.
core   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

open access: yesAdvanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She   +14 more
wiley   +1 more source

Gene Transfer Among Viruses Substantially Contributes to Gene Gain of Giant Viruses. [PDF]

open access: yesMol Biol Evol, 2023
Abstract The phylum Nucleocytoviricota comprises a diverse group of double-stranded DNA viruses that display a wide range of gene repertoires. Although these gene repertoires determine the characteristics of individual viruses, the evolutionary processes that have shaped the gene repertoires of extant viruses since their common ...
Wu J   +6 more
europepmc   +3 more sources

Panspermia, Past and Present: Astrophysical and Biophysical Conditions for the Dissemination of Life in Space

open access: yes, 2010
Astronomically, there are viable mechanisms for distributing organic material throughout the Milky Way. Biologically, the destructive effects of ultraviolet light and cosmic rays means that the majority of organisms arrive broken and dead on a new world.
A.A. Sharov   +65 more
core   +1 more source

Characteristics of virophages and giant viruses

open access: yesActa Biochimica Polonica, 2018
Five years after being discovered in 2003, some giant viruses were demonstrated to play a role of the hosts for virophages, their parasites, setting out a novel and yet unknown regulatory mechanism of the giant viruses presence in an aqueous. So far, 20 virophages have been registered and 13 of them have been described as a metagenomic material, which ...
Wiesław Deptuła   +3 more
openaire   +3 more sources

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

open access: yesAdvanced Science, EarlyView.
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera   +10 more
wiley   +1 more source

The friendship paradox in scale-free networks [PDF]

open access: yes, 2014
Our friends have more friends than we do. That is the basis of the friendship paradox. In mathematical terms, the mean number of friends of friends is higher than the mean number of friends.
Amaku, Marcos   +4 more
core   +2 more sources

Genomic exploration of individual giant ocean viruses [PDF]

open access: yesThe ISME Journal, 2017
Abstract Viruses are major pathogens in all biological systems. Virus propagation and downstream analysis remains a challenge, particularly in the ocean where the majority of their microbial hosts remain recalcitrant to current culturing techniques.
William H Wilson   +10 more
openaire   +2 more sources

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