Results 31 to 40 of about 20,965 (245)

Proteorhodopsin genes in giant viruses [PDF]

open access: yesBiology Direct, 2012
Viruses with large genomes encode numerous proteins that do not directly participate in virus biogenesis but rather modify key functional systems of infected cells. We report that a distinct group of giant viruses infecting unicellular eukaryotes that includes Organic Lake Phycodnaviruses and Phaeocystis globosa virus encode predicted proteorhodopsins ...
Yutin Natalya, Koonin Eugene V
openaire   +3 more sources

Giant virus vs amoeba: fight for supremacy

open access: yesVirology Journal, 2019
Since the discovery of mimivirus, numerous giant viruses associated with free-living amoebae have been described. The genome of giant viruses can be more than 2.5 megabases, and virus particles can exceed the size of many bacteria.
Graziele Oliveira   +2 more
doaj   +1 more source

Near-atomic, non-icosahedrally averaged structure of giant virus Paramecium bursaria chlorella virus 1

open access: yesNature Communications, 2022
Giant viruses are large DNA viruses with capsid diameters up to 500 nm. Given technical challenges only few high-resolution structures of viral capsids exist. Here, Shao et al.
Qianqian Shao   +12 more
doaj   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

open access: yesHepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam   +10 more
wiley   +1 more source

Giant viruses of the Kutch Desert [PDF]

open access: yesArchives of Virology, 2015
The Kutch desert (Great Rann of Kutch, Gujarat, India) is a unique ecosystem: in the larger part of the year it is a hot, salty desert that is flooded regularly in the Indian monsoon season. In the dry season, the crystallized salt deposits form the "white desert" in large regions.
Csaba Kerepesi, Vince Grolmusz
openaire   +3 more sources

20 years of research on giant viruses. [PDF]

open access: yesNpj Viruses
Abstract Some twenty years ago, the discovery of the first giant virus, Acanthamoeba polyphaga mimivirus (now mimivirus bradfordmassiliense species), paved the way for the discovery of more than 10 new families of protist-infecting DNA viruses with unexpected diversity in virion shape and size, gene content, genome topology and mode of ...
Bosmon T, Abergel C, Claverie JM.
europepmc   +5 more sources

From Mimivirus to Mirusvirus: The Quest for Hidden Giants

open access: yesViruses, 2023
Our perception of viruses has been drastically evolving since the inception of the field of virology over a century ago. In particular, the discovery of giant viruses from the Nucleocytoviricota phylum marked a pivotal moment.
Morgan Gaïa, Patrick Forterre
doaj   +1 more source

Virome comparisons in wild-diseased and healthy captive giant pandas

open access: yesMicrobiome, 2017
Background The giant panda (Ailuropoda melanoleuca) is a vulnerable mammal herbivore living wild in central China. Viral infections have become a potential threat to the health of these endangered animals, but limited information related to these ...
Wen Zhang   +20 more
doaj   +1 more source

A Brief History of Giant Viruses’ Studies in Brazilian Biomes

open access: yesViruses, 2022
Almost two decades after the isolation of the first amoebal giant viruses, indubitably the discovery of these entities has deeply affected the current scientific knowledge on the virosphere. Much has been uncovered since then: viruses can now acknowledge
Paulo Victor M. Boratto   +16 more
doaj   +1 more source

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